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Identifying reliable biomarkers for predicting clinical events in longitudinal studies is important for accurate disease prognosis and for guiding development of new treatments. However, prognostic studies are often observational, making it…

Methodology · Statistics 2025-08-12 Ainesh Sewak , Vanda Inacio , Joanne Wuu , Michael Benatar , Torsten Hothorn

Learning meaningful representations from medical time series (MedTS) such as ECG or EEG signals is a critical challenge. These signals are often high-dimensional, variable-length and rife with noise. Existing self-supervised approaches,…

Machine Learning · Computer Science 2026-05-04 Huayu Li , ZhengXiao He , Xiwen Chen , Jingjing Wang , Siyuan Tian , Jinghao Wen , Ao Li

Generating forecasts for time series with multiple seasonal cycles is an important use-case for many industries nowadays. Accounting for the multi-seasonal patterns becomes necessary to generate more accurate and meaningful forecasts in…

Applications · Statistics 2020-04-28 Kasun Bandara , Christoph Bergmeir , Hansika Hewamalage

The next great leap toward improving treatment of cancer with radiation will require the combined use of online adaptive and magnetic resonance guided radiation therapy techniques with automatic X-ray beam orientation selection.…

Medical Physics · Physics 2019-08-14 Ryan Neph , Yangsibo Huang , Youming Yang , Ke Sheng

Convolutional neural networks (CNNs) are used in many embedded applications, from industrial robotics and automation systems to biometric identification on mobile devices. State-of-the-art classification is typically achieved by large…

Machine Learning · Computer Science 2020-05-22 Yuan Wen , Andrew Anderson , Valentin Radu , Michael F. P. O'Boyle , David Gregg

The individual data collected throughout patient follow-up constitute crucial information for assessing the risk of a clinical event, and eventually for adapting a therapeutic strategy. Joint models and landmark models have been proposed to…

Machine Learning · Statistics 2024-07-17 Anthony Devaux , Robin Genuer , Karine Pérès , Cécile Proust-Lima

Electronic Health Records (EHRs) enable deep learning for clinical predictions, but the optimal method for representing patient data remains unclear due to inconsistent evaluation practices. We present the first systematic benchmark to…

Machine Learning · Computer Science 2025-10-13 Tianyi Chen , Mingcheng Zhu , Zhiyao Luo , Tingting Zhu

Monitoring and analyzing electrocardiogram (ECG) signals, even under varying physiological conditions, including those influenced by physical activity, drugs and stress, is crucial to accurately assess cardiac health. However, current…

Computer Vision and Pattern Recognition · Computer Science 2025-05-13 Ahmad Fall , Federica Granese , Alex Lence , Dominique Fourer , Blaise Hanczar , Joe-Elie Salem , Jean-Daniel Zucker , Edi Prifti

While diffusion models have set a new benchmark for quality in Low-Dose Computed Tomography (LDCT) denoising, their clinical adoption is critically hindered by extreme computational costs, with inference times often exceeding thousands of…

Computer Vision and Pattern Recognition · Computer Science 2025-09-30 Tangtangfang Fang , Jingxi Hu , Xiangjian He , Jiaqi Yang

Internet of Things (IoT)-based healthcare systems offer significant potential for improving healthcare delivery in humanitarian and resource-constrained environments, providing essential services to underserved populations in remote areas.…

Image and Video Processing · Electrical Eng. & Systems 2026-02-11 Omar H. Khater , Basem Almadani , Farouq Aliyu , Esam Al-Nahari

Despite the unprecedented performance of deep neural networks (DNNs) in computer vision, their practical application in the diagnosis and prognosis of cancer using medical imaging has been limited. One of the critical challenges for…

Machine Learning · Computer Science 2023-04-27 Lennart Brocki , Neo Christopher Chung

Purpose: Automated medical image-based prediction of clinical outcomes, such as overall survival (OS), has great potential in improving patient prognostics and personalized treatment planning. We developed a deep regression framework using…

Computer Vision and Pattern Recognition · Computer Science 2026-05-25 Sambit Tarai , Ashish Chauhan , Elin Lundström , Johan Öfverstedt , Therese Sjöholm , Veronica Sanchez Rodriguez , Håkan Ahlström , Joel Kullberg

Clinical trial outcome prediction seeks to estimate the likelihood that a clinical trial will successfully reach its intended endpoint. This process predominantly involves the development of machine learning models that utilize a variety of…

Biomolecules · Quantitative Biology 2024-05-14 Chufan Gao , Tianfan Fu , Jimeng Sun

Screening and surveillance are routinely used in medicine for early detection of disease and close monitoring of progression. Biomarkers are one of the primarily tools used for these tasks, but their successful translation to clinical…

The Internet of Medical Things (IoMT) has dramatically benefited medical professionals that patients and physicians can access from all regions. Although the automatic detection and prediction of diseases such as melanoma and leukemia is…

Computer Vision and Pattern Recognition · Computer Science 2023-12-13 Alhassan Mabrouk , Abdelghani Dahou , Mohamed Abd Elaziz , Rebeca P. Díaz Redondo , Mohammed Kayed

Predicting clinical outcome is remarkably important but challenging. Research efforts have been paid on seeking significant biomarkers associated with the therapy response or/and patient survival. However, these biomarkers are generally…

Machine Learning · Computer Science 2020-10-09 Jiancheng Yang , Jiajun Chen , Kaiming Kuang , Tiancheng Lin , Junjun He , Bingbing Ni

Recently, with the advent of deep convolutional neural networks (DCNN), the improvements in visual saliency prediction research are impressive. One possible direction to approach the next improvement is to fully characterize the multi-scale…

Computer Vision and Pattern Recognition · Computer Science 2019-05-10 Sheng Yang , Guosheng Lin , Qiuping Jiang , Weisi Lin

Skin lesion is a severe disease in world-wide extent. Early detection of melanoma in dermoscopy images significantly increases the survival rate. However, the accurate recognition of melanoma is extremely challenging due to the following…

Computer Vision and Pattern Recognition · Computer Science 2017-11-23 Yuexiang Li , Linlin Shen

Traditional machine learning methods face two main challenges in dealing with healthcare predictive analytics tasks. First, the high-dimensional nature of healthcare data needs labor-intensive and time-consuming processes to select an…

Machine Learning · Computer Science 2022-09-16 Mohammad Amin Morid , Olivia R. Liu Sheng , Joseph Dunbar

We present BiTimeCrossNet (BTCNet), a multimodal self-supervised learning framework for long physiological recordings such as overnight sleep studies. While many existing approaches train on short segments treated as independent samples,…

Machine Learning · Computer Science 2026-02-04 Saurav Raj Pandey , Harlin Lee