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Circadian rhythms influence multiple essential biological activities including sleep, performance, and mood. The dim light melatonin onset (DLMO) is the gold standard for measuring human circadian phase (i.e., timing). The collection of…

Machine Learning · Computer Science 2022-03-03 Cheng Wan , Andrew W. McHill , Elizabeth Klerman , Akane Sano

The response time of a biosensor is a crucial metric in safety-critical applications such as medical diagnostics where an earlier diagnosis can markedly improve patient outcomes. However, the speed at which a biosensor reaches a final…

Machine Learning · Computer Science 2024-09-30 Simon J. Ward , Muhamed Baljevic , Sharon M. Weiss

Early and accurate prediction of overall survival (OS) time can help to obtain better treatment planning for brain tumor patients. Although many OS time prediction methods have been developed and obtain promising results, there are still…

Image and Video Processing · Electrical Eng. & Systems 2020-07-16 Tao Zhou , Huazhu Fu , Yu Zhang , Changqing Zhang , Xiankai Lu , Jianbing Shen , Ling Shao

Multivariate time series forecasting is an important machine learning problem across many domains, including predictions of solar plant energy output, electricity consumption, and traffic jam situation. Temporal data arise in these…

Machine Learning · Computer Science 2018-04-20 Guokun Lai , Wei-Cheng Chang , Yiming Yang , Hanxiao Liu

To facilitate early detection of breast cancer, there is a need to develop short-term risk prediction schemes that can prescribe personalized/individualized screening mammography regimens for women. In this study, we propose a new deep…

Image and Video Processing · Electrical Eng. & Systems 2024-12-05 Hong Hui Yeoh , Fredrik Strand , Raphaël Phan , Kartini Rahmat , Maxine Tan

Accurate gene regulatory networks can be used to explain the emergence of different phenotypes, disease mechanisms, and other biological functions. Many methods have been proposed to infer networks from gene expression data but have been…

Quantitative Methods · Quantitative Biology 2018-12-11 Phan Nguyen , Rosemary Braun

Objective: In randomized clinical trials, prediction models can be used to explore the relationships between patients' variables (e.g., clinical, pathological, or lifestyle variables, and also biomarker or genomic data) and treatment effect…

Quantitative Methods · Quantitative Biology 2026-02-03 Elvire Roblin , Paul-Henry Cournède , Stefan Michiels

Real-time prediction of clinical interventions remains a challenge within intensive care units (ICUs). This task is complicated by data sources that are noisy, sparse, heterogeneous and outcomes that are imbalanced. In this paper, we…

Machine Learning · Computer Science 2017-05-25 Harini Suresh , Nathan Hunt , Alistair Johnson , Leo Anthony Celi , Peter Szolovits , Marzyeh Ghassemi

Therapeutic intervention in neurological disorders still relies heavily on pharmacological solutions, while the treatment of patients with drug resistance remains an open challenge. This is particularly true for patients with epilepsy, 30%…

Human-Computer Interaction · Computer Science 2022-10-20 Margherita Ronchini , Yasser Rezaeiyan , Milad Zamani , Gabriella Panuccio , Farshad Moradi

Early management and better clinical outcomes for epileptic patients depend on seizure prediction. The accuracy and false alarm rates of existing systems are often compromised by their dependence on static thresholds and basic…

Signal Processing · Electrical Eng. & Systems 2025-01-29 Mathan Kumar Mounagurusamy , Thiyagarajan V S , Abdur Rahman , Shravan Chandak , D. Balaji , Venkateswara Rao Jallepalli

The increasing integration of the Internet of Medical Things (IoMT) into healthcare systems has significantly enhanced patient care but has also introduced critical cybersecurity challenges. This paper presents a novel approach based on…

Cryptography and Security · Computer Science 2025-02-24 Alireza Mohamadi , Hosna Ghahramani , Seyyed Amir Asghari , Mehdi Aminian

This paper focuses on the task of survival time analysis for lung cancer. Although much progress has been made in this problem in recent years, the performance of existing methods is still far from satisfactory. Traditional and some deep…

Computer Vision and Pattern Recognition · Computer Science 2022-11-08 Yujiao Wu , Yaxiong Wang , Xiaoshui Huang , Fan Yang , Sai Ho Ling , Steven Weidong Su

Extensive bedside monitoring in Intensive Care Units (ICUs) has resulted in complex temporal data regarding patient physiology, which presents an upscale context for clinical data analysis. In the other hand, identifying the time-series…

Machine Learning · Computer Science 2023-08-25 Manel Mili , Asma Kerkeni , Asma Ben Abdallah , Mohamed Hedi Bedoui

Early and timely prediction of patient care demand not only affects effective resource allocation but also influences clinical decision-making as well as patient experience. Accurately predicting patient care demand, however, is a…

Machine Learning · Computer Science 2024-04-30 Annie Hu , Samuel Stockman , Xun Wu , Richard Wood , Bangdong Zhi , Oliver Y. Chén

The problem of dynamic prediction with time-dependent covariates, given by biomarkers, repeatedly measured over time, has received much attention over the last decades. Two contrasting approaches have become in widespread use. The first is…

Methodology · Statistics 2021-03-31 Hein Putter , Hans C. van Houwelingen

The high dimensionality and complexity of neuroimaging data necessitate large datasets to develop robust and high-performing deep learning models. However, the neuroimaging field is notably hampered by the scarcity of such datasets. In this…

Machine Learning · Computer Science 2023-12-15 Yutong Gao , Charles A. Ellis , Vince D. Calhoun , Robyn L. Miller

Background: During the early stages of hospital admission, clinicians must use limited information to make diagnostic and treatment decisions as patient acuity evolves. However, it is common that the time series vital sign information from…

Overall survival (OS) time is one of the most important evaluation indices for gliomas situations. Multimodal Magnetic Resonance Imaging (MRI) scans play an important role in the study of glioma prognosis OS time. Several deep…

Image and Video Processing · Electrical Eng. & Systems 2024-04-19 Wen Tang , Haoyue Zhang , Pengxin Yu , Han Kang , Rongguo Zhang

The cosinor model is frequently used to represent the oscillatory behavior of different genes over time. When data are collected from multiple individuals, the cosinor model is estimated with recorded gene expression levels and the 24 hour…

Applications · Statistics 2024-07-18 Michael T. Gorczyca

In recent years, continuous latent space (CLS) and discrete latent space (DLS) deep learning models have been proposed for medical image analysis for improved performance. However, these models encounter distinct challenges. CLS models…

Computer Vision and Pattern Recognition · Computer Science 2023-10-30 Vandan Gorade , Sparsh Mittal , Debesh Jha , Ulas Bagci
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