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Maternal exposure to air pollution during pregnancy has a substantial public health impact. Epidemiological evidence supports an association between maternal exposure to air pollution and low birth weight. A popular method to estimate this…

Distributed lag models are useful in environmental epidemiology as they allow the user to investigate critical windows of exposure, defined as the time period during which exposure to a pollutant adversely affects health outcomes. Recent…

Methodology · Statistics 2021-08-02 Joseph Antonelli , Ander Wilson , Brent Coull

Children's health studies support an association between maternal environmental exposures and children's birth outcomes. A common goal is to identify critical windows of susceptibility--periods during gestation with increased association…

Epidemiological research supports an association between maternal exposure to air pollution during pregnancy and adverse children's health outcomes. Advances in exposure assessment and statistics allow for estimation of both critical…

An important goal of environmental health research is to assess the health risks posed by mixtures of multiple environmental exposures. In these mixtures analyses, flexible models like Bayesian kernel machine regression and multiple index…

Methodology · Statistics 2025-12-29 Glen McGee , Joseph Antonelli

Exposure to environmental pollutants during the gestational period can significantly impact infant health outcomes, such as birth weight and neurological development. Identifying critical windows of susceptibility, which are specific…

Applications · Statistics 2024-08-19 Yisen Jin , Aaron J. Molstad , Ander Wilson , Joseph Antonelli

In studies of maternal exposure to air pollution a children's health outcome is regressed on exposures observed during pregnancy. The distributed lag nonlinear model (DLNM) is a statistical method commonly implemented to estimate an…

Methodology · Statistics 2021-06-16 Daniel Mork , Ander Wilson

Exposures to environmental chemicals during gestation can alter health status later in life. Most studies of maternal exposure to chemicals during pregnancy have focused on a single chemical exposure observed at high temporal resolution.…

This study quantifies the association between air pollution and mortality in Ontario, Canada. Exposure-response relationships in air pollution epidemiology are complex due to three features: time-lagged associations, non-linear…

Methodology · Statistics 2026-04-27 Tianyi Pan , Hwashin Hyun Shin , Alex Stringer , Glen McGee

Quantifying associations between short-term exposure to ambient air pollution and health outcomes is an important public health priority. Many studies have investigated the association considering delayed effects within the past few days.…

Methodology · Statistics 2025-05-22 Tianyi Pan , Hwashin Hyun Shin , Glen McGee , Alex Stringer

Environmental exposures, such as air pollution and extreme temperatures, have complex effects on human health. These effects are often characterized by non-linear exposure-lag-response relationships and delayed impacts over time. Accurately…

Methodology · Statistics 2025-12-02 Álvaro Briz-Redón , Ana Corberán-Vallet , Adina Iftimi , Carmen Íñiguez

Humans are exposed to complex mixtures of environmental pollutants rather than single chemicals, necessitating methods to quantify the health effects of such mixtures. Research on environmental mixtures provides insights into realistic…

Methodology · Statistics 2026-04-09 Aaron Sonabend , Jiangshan Zhang , Edgar Castro , Joel Schwartz , Brent A. Coull , Junwei Lu

Maternal exposure to environmental chemicals during pregnancy can alter birth and children's health outcomes. Research seeks to identify critical windows, time periods when the exposures can change future health outcomes, and estimate the…

Methodology · Statistics 2022-04-14 Daniel Mork , Ander Wilson

Recent studies of associations between environmental exposures and health outcomes have shifted toward estimating the effect of simultaneous exposure to multiple chemicals. Summary index methods, such as the weighted quantile sum and…

Applications · Statistics 2025-02-21 Jacob Englert , Howard Chang

The relationship between short-term exposure to air pollution and mortality or morbidity has been the subject of much recent research, in which the standard method of analysis uses Poisson linear or additive models. In this paper we use a…

Applications · Statistics 2012-01-27 Duncan Lee , Gavin Shaddick

Distributed Lag Models (DLMs) and similar regression approaches such as MIDAS have been used for many decades in econometrics and more recently to investigate how poor air quality adversely affects human health. In this paper we describe…

Methodology · Statistics 2025-01-30 Daniel Dempsey , Jason Wyse

An important goal of environmental health research is to assess the risk posed by mixtures of environmental exposures. Two popular classes of models for mixtures analyses are response-surface methods and exposure-index methods.…

Methodology · Statistics 2025-05-01 Glen McGee , Ander Wilson , Thomas F. Webster , Brent A. Coull

We develop new methodology to improve our understanding of the causal effects of multivariate air pollution exposures on public health. Typically, exposure to air pollution for an individual is measured at their home geographic region,…

Methodology · Statistics 2025-11-18 Heejun Shin , Danielle Braun , Kezia Irene , Michelle Audirac , Joseph Antonelli

This paper investigates whether associations between birth weight and prenatal ambient environmental conditions--pollution and extreme temperatures--differ by 1) maternal education; 2) children's innate health; and 3) interactions between…

General Economics · Economics 2022-04-04 Xiaoying Liu , Jere R. Behrman , Emily Hannum , Fan Wang , Qingguo Zhao

Studies of the relationships between environmental exposures and adverse health outcomes often rely on a two-stage statistical modeling approach, where exposure is modeled/predicted in the first stage and used as input to a separately fit…

Methodology · Statistics 2022-04-01 Saskia Comess , Howard H. Chang , Joshua L. Warren
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