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Animal cells use traction forces to sense the mechanics and geometry of their environment. Measuring these traction forces requires a workflow combining cell experiments, image processing and force reconstruction based on elasticity theory.…

Quantitative Methods · Quantitative Biology 2016-08-24 Jerome R. Soine , Nils Hersch , Georg Dreissen , Nico Hampe , Bernd Hoffmann , Rudolf Merkel , Ulrich S. Schwarz

In this paper, we propose a new approach to deformable image registration that captures sliding motions. The large deformation diffeomorphic metric mapping (LDDMM) registration method faces challenges in representing sliding motion since it…

Optimization and Control · Mathematics 2023-03-15 Lili Bao , Jiahao Lu , Shihui Ying , Stefan Sommer

In computational anatomy, the statistical analysis of temporal deformations and inter-subject variability relies on shape registration. However, the numerical integration and optimization required in diffeomorphic registration often lead to…

Graphics · Computer Science 2019-06-17 N. Guigui , Shuman Jia , Maxime Sermesant , Xavier Pennec

This paper discusses the mathematical framework for designing methods of large deformation matching (LDM) for image registration in computational anatomy. After reviewing the geometrical framework of LDM image registration methods, a…

Chaotic Dynamics · Physics 2015-04-09 M. Bruveris , F. Gay-Balmaz , D. D. Holm , T. S. Ratiu

Valvular heart disease is prevalent and a major contributor to heart failure. Valve leaflet strain is a promising metric for evaluating the mechanics underlying the initiation and progression of valvular pathology. However, generalizable…

Quantitative Methods · Quantitative Biology 2026-02-25 Wensi Wu , Matthew Daemer , Jeffrey A. Weiss , Alison M. Pouch , Matthew A. Jolley

Purpose: This study proposes a novel anatomically-driven dynamic modeling framework for coronary arteries using skeletal skinning weights computation, aiming to achieve precise control over vessel deformation while maintaining real-time…

Graphics · Computer Science 2025-03-05 Shuo Wang , Tong Ren , Nan Cheng , Rong Wang , Li Zhang

Diffusion models have recently gained immense interest for their generative capabilities, specifically the high quality and diversity of the synthesized data. However, examples of their applications in 3D medical imaging are still scarce,…

Image and Video Processing · Electrical Eng. & Systems 2025-08-21 Jolanta Mozyrska , Marcel Beetz , Luke Melas-Kyriazi , Vicente Grau , Abhirup Banerjee , Alfonso Bueno-Orovio

Abdominal organ segmentation from CT and MRI is an essential prerequisite for surgical planning and computer-aided navigation systems. It is challenging due to the high variability in the shape, size, and position of abdominal organs.…

Computer Vision and Pattern Recognition · Computer Science 2023-10-31 Fabian Bongratz , Anne-Marie Rickmann , Christian Wachinger

In deformable registration, the geometric framework - large deformation diffeomorphic metric mapping or LDDMM, in short - has inspired numerous techniques for comparing, deforming, averaging and analyzing shapes or images. Grounded in…

Artificial Intelligence · Computer Science 2022-05-11 Boulbaba Ben Amor , Sylvain Arguillère , Ling Shao

Functional analysis of the left atrium (LA) plays an increasingly important role in the prognosis and diagnosis of cardiovascular diseases. Echocardiography-based measurements of LA dimensions and strains are useful biomarkers, but they…

Image and Video Processing · Electrical Eng. & Systems 2023-09-06 Christoforos Galazis , Anil Anthony Bharath , Marta Varela

Computational fluid dynamics (CFD) is a valuable tool for personalised, non-invasive evaluation of hemodynamics in arteries, but its complexity and time-consuming nature prohibit large-scale use in practice. Recently, the use of deep…

Machine Learning · Computer Science 2022-01-21 Julian Suk , Pim de Haan , Phillip Lippe , Christoph Brune , Jelmer M. Wolterink

Tissue deformation in ultrasound (US) imaging leads to geometrical errors when measuring tissues due to the pressure exerted by probes. Such deformation has an even larger effect on 3D US volumes as the correct compounding is limited by the…

Image and Video Processing · Electrical Eng. & Systems 2021-10-26 Zhongliang Jiang , Yue Zhou , Yuan Bi , Mingchuan Zhou , Thomas Wendler , Nassir Navab

Muscle volume is a useful quantitative biomarker in sports, but also for the follow-up of degenerative musculo-skelletal diseases. In addition to volume, other shape biomarkers can be extracted by segmenting the muscles of interest from…

Computer Vision and Pattern Recognition · Computer Science 2023-11-01 Louise Piecuch , Vanessa Gonzales Duque , Aurélie Sarcher , Enzo Hollville , Antoine Nordez , Giuseppe Rabita , Gaël Guilhem , Diana Mateus

Anatomy is undergoing a renaissance driven by availability of large digital data sets generated by light microscopy. A central computational task is to map individual data volumes to standardized templates. This is accomplished by…

Image and Video Processing · Electrical Eng. & Systems 2018-09-19 Daniel J. Tward , Partha Mitra , Michael I. Miller

The modeling of large deformation fracture mechanics has been a challenging problem regarding the accuracy of numerical methods and their ability to deal with considerable changes in deformations of meshes where having the presence of…

Numerical Analysis · Computer Science 2019-03-21 Hai D. Huynh , Phuong Tran , Xiaoying Zhuang , H. Nguyen-Xuan

Cardiopulmonary resuscitation (CPR) is an emergency procedure performed on patients during cardiac and respiratory arrest. This procedure externally activates the cardiac and respiratory systems via the delivery of chest compression and…

Numerical Analysis · Mathematics 2022-06-01 Jafar Moradicheghamahi , Gerard Fortuny , Josep M. López , Joan Herrero , Dolors Puigjaner

We present a method to predict image deformations based on patch-wise image appearance. Specifically, we design a patch-based deep encoder-decoder network which learns the pixel/voxel-wise mapping between image appearance and registration…

Computer Vision and Pattern Recognition · Computer Science 2016-07-11 Xiao Yang , Roland Kwitt , Marc Niethammer

We introduce an unsupervised motion-compensated image reconstruction algorithm for free-breathing and ungated 3D cardiac magnetic resonance imaging (MRI). We express the image volume corresponding to each specific motion phase as the…

Computer Vision and Pattern Recognition · Computer Science 2025-06-03 Joseph Kettelkamp , Ludovica Romanin , Sarv Priya , Mathews Jacob

The ability to map left ventricle (LV) myocardial motion using computed tomography angiography (CTA) is essential to diagnosing cardiovascular conditions and guiding interventional procedures. Due to their inherent locality, conventional…

Image and Video Processing · Electrical Eng. & Systems 2024-11-08 Shahar Zuler , Shai Tejman-Yarden , Dan Raviv

Dark-field X-ray Microscopy (DFXM) is a novel diffraction-based imaging technique that non-destructively maps the local deformation from crystalline defects in bulk materials. While studies have demonstrated that DFXM can spatially map 3D…