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Delineation of anatomical structures is often the first step of many medical image analysis workflows. While convolutional neural networks achieve high performance, these do not incorporate anatomical shape information. We introduce a novel…

Image and Video Processing · Electrical Eng. & Systems 2023-10-18 Athira J Jacob , Puneet Sharma , Daniel Ruckert

In the study of shapes of human organs using computational anatomy, variations are found to arise from inter-subject anatomical differences, disease-specific effects, and measurement noise. This paper introduces a stochastic model for…

Computer Vision and Pattern Recognition · Computer Science 2016-12-19 Alexis Arnaudon , Darryl D. Holm , Akshay Pai , Stefan Sommer

Automated construction of surface geometries of cardiac structures from volumetric medical images is important for a number of clinical applications. While deep-learning-based approaches have demonstrated promising reconstruction precision,…

Image and Video Processing · Electrical Eng. & Systems 2021-09-15 Fanwei Kong , Nathan Wilson , Shawn C. Shadden

Accurate 3D cardiac reconstruction from cine magnetic resonance imaging (cMRI) is crucial for improved cardiovascular disease diagnosis and understanding of the heart's motion. However, current cardiac MRI-based reconstruction technology…

Image and Video Processing · Electrical Eng. & Systems 2023-08-21 Xiaoxiao He , Chaowei Tan , Ligong Han , Bo Liu , Leon Axel , Kang Li , Dimitris N. Metaxas

Image-based computer simulation of cardiac function can be used to probe the mechanisms of (patho)physiology, and guide diagnosis and personalized treatment of cardiac diseases. This paradigm requires constructing simulation-ready meshes of…

Image and Video Processing · Electrical Eng. & Systems 2021-07-23 Fanwei Kong , Shawn C. Shadden

Spatially localized deformation components are very useful for shape analysis and synthesis in 3D geometry processing. Several methods have recently been developed, with an aim to extract intuitive and interpretable deformation components.…

Graphics · Computer Science 2017-12-19 Qingyang Tan , Lin Gao , Yu-Kun Lai , Jie Yang , Shihong Xia

Motion and deformation analysis of cardiac magnetic resonance (CMR) imaging videos is crucial for assessing myocardial strain of patients with abnormal heart functions. Recent advances in deep learning-based image registration algorithms…

Computer Vision and Pattern Recognition · Computer Science 2024-12-10 Jiarui Xing , Nivetha Jayakumar , Nian Wu , Yu Wang , Frederick H. Epstein , Miaomiao Zhang

Accurate tracking of an anatomical landmark over time has been of high interests for disease assessment such as minimally invasive surgery and tumor radiation therapy. Ultrasound imaging is a promising modality benefiting from low-cost and…

Computer Vision and Pattern Recognition · Computer Science 2023-02-01 Zhihua Liu , Bin Yang , Yan Shen , Xuejun Ni , Huiyu Zhou

Purpose: The mechanics of the mitral valve leaflet as a nonlinear, inelastic and anisotropic soft tissue results from an integrated response of many mathematical/physical indexes' that illustrate the tissue. In the past decade, finite…

Medical Physics · Physics 2015-06-24 Mersedeh Karvandi , Saeed Ranjbar , Seyed Ahmad Hassantash , Mahnoosh Foroughi

This paper describes how Large Deformation Diffeomorphic Metric Mapping (LDDMM) can be coupled with a Fast Multipole (FM) Boundary Element Method (BEM) to investigate the relationship between morphological changes in the head, torso, and…

Computational Geometry · Computer Science 2016-11-17 Reza Zolfaghari , Nicolas Epain , Craig T. Jin , Joan Glaunès , Anthony Tew

Learning spatial-temporal correspondences in cardiac motion from images is important for understanding the underlying dynamics of cardiac anatomical structures. Many methods explicitly impose smoothness constraints such as the…

Image and Video Processing · Electrical Eng. & Systems 2022-09-05 Xiaoran Zhang , Chenyu You , Shawn Ahn , Juntang Zhuang , Lawrence Staib , James Duncan

In computational anatomy, the Large Deformation Diffeomorphic Metric Mapping (LDDMM) framework has become a central tool for modeling smooth, invertible transformations between shapes such as curves or landmarks. In this paper, we extend…

Differential Geometry · Mathematics 2025-11-19 Rayane Mouhli , Thomas Pierron

Cardiac magnetic resonance (CMR) sequences visualise the cardiac function voxel-wise over time. Simultaneously, deep learning-based deformable image registration is able to estimate discrete vector fields which warp one time step of a CMR…

Computer Vision and Pattern Recognition · Computer Science 2022-09-20 Sven Koehler , Tarique Hussain , Hamza Hussain , Daniel Young , Samir Sarikouch , Thomas Pickhardt , Gerald Greil , Sandy Engelhardt

Modelling deformation of anatomical objects observed in medical images can help describe disease progression patterns and variations in anatomy across populations. We apply a stochastic generalisation of the Large Deformation Diffeomorphic…

Statistics Theory · Mathematics 2018-12-14 Line Kühnel , Alexis Arnaudon , Tom Fletcher , Stefan Sommer

Four-dimensional (4D) left ventricular myocardial velocity mapping (MVM) is a cardiac magnetic resonance (CMR) technique that allows assessment of cardiac motion in three orthogonal directions. Accurate and reproducible delineation of the…

Image and Video Processing · Electrical Eng. & Systems 2020-12-23 Yinzhe Wu , Suzan Hatipoglu , Diego Alonso-Álvarez , Peter Gatehouse , David Firmin , Jennifer Keegan , Guang Yang

Diffusion tensor cardiac magnetic resonance (DT-CMR) is a method capable of providing non-invasive measurements of myocardial microstructure. Image registration is essential to correct image shifts due to intra and inter breath-hold motion…

Image and Video Processing · Electrical Eng. & Systems 2024-05-17 Fanwen Wang , Pedro F. Ferreira , Yinzhe Wu , Camila Munoz , Ke Wen , Yaqing Luo , Jiahao Huang , Dudley J. Pennell , Andrew D. Scott , Sonia Nielles-Vallespin , Guang Yang

Anatomical variabilities seen in longitudinal data or inter-subject data is usually described by the underlying deformation, captured by non-rigid registration of these images. Stationary Velocity Field (SVF) based non-rigid registration…

Computer Vision and Pattern Recognition · Computer Science 2021-01-05 Alphin J. Thottupattu , Jayanthi Sivaswamy , Venkateswaran P. Krishnan

We develop an operator splitting approach to solve diffeomorphic matching problems for sequences of surfaces in three-dimensional space. The goal is to smoothly match, at a very fast rate, finite sequences of observed 3D-snapshots extracted…

Optimization and Control · Mathematics 2022-07-12 Peng Zhang , Andreas Mang , Jiwen He , Robert Azencott , K. Carlos El-Tallawi , William A. Zoghbi

Patient-specific cardiac modeling combines geometries of the heart derived from medical images and biophysical simulations to predict various aspects of cardiac function. However, generating simulation-suitable models of the heart from…

Image and Video Processing · Electrical Eng. & Systems 2023-11-09 Fanwei Kong , Shawn Shadden

Cardiac parametric mapping is useful for evaluating cardiac fibrosis and edema. Parametric mapping relies on single-shot heartbeat-by-heartbeat imaging, which is susceptible to intra-shot motion during the imaging window. However, reducing…

Image and Video Processing · Electrical Eng. & Systems 2025-03-25 Calder D. Sheagren , Brenden T. Kadota , Jaykumar H. Patel , Mark Chiew , Graham A. Wright