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Rapid discovery of new reactions and molecules in recent years has been facilitated by the advancements in high throughput screening, accessibility to a much more complex chemical design space, and the development of accurate molecular…

Molecular Networks · Quantitative Biology 2023-03-28 Vipul Mann , Venkat Venkatasubramanian

Evaluating node importance is a critical aspect of analyzing complex systems, with broad applications in digital marketing, rumor suppression, and disease control. However, existing methods typically rely on conventional network structures…

Social and Information Networks · Computer Science 2025-07-29 Xiaonan Ni , Guangyuan Mei , Su-Su Zhang , Yang Chen , Xin Xu , Chuang Liu , Xiu-Xiu Zhan

A directed hypergraph (dihypergraph) consists of a set of vertices and a set of hyperarcs, where each hyperarc is partitioned into a head and a tail. Directed hypergraphs are useful in many applications, including the study of chemical…

Combinatorics · Mathematics 2026-04-14 Catherine Greenhill , Tamás Makai

Hypergraphs provide a natural way of representing group relations, whose complexity motivates an extensive array of prior work to adopt some form of abstraction and simplification of higher-order interactions. However, the following…

Social and Information Networks · Computer Science 2020-05-14 Se-eun Yoon , Hyungseok Song , Kijung Shin , Yung Yi

Networks can describe the structure of a wide variety of complex systems by specifying which pairs of entities in the system are connected. While such pairwise representations are flexible, they are not necessarily appropriate when the…

Social and Information Networks · Computer Science 2022-01-17 Jean-Gabriel Young , Giovanni Petri , Tiago P. Peixoto

Higher-order connectivity patterns such as small induced sub-graphs called graphlets (network motifs) are vital to understand the important components (modules/functional units) governing the configuration and behavior of complex networks.…

Social and Information Networks · Computer Science 2020-09-15 Aldo G. Carranza , Ryan A. Rossi , Anup Rao , Eunyee Koh

A temporal (directed) graph is a graph whose edges are available only at specific times during its lifetime, $\tau$. Paths are sequences of adjacent edges whose appearing times are either strictly increasing or non-strictly increasingly…

Combinatorics · Mathematics 2023-03-01 Isnard Lopes Costa , Raul Lopes , Andrea Marino , Ana Silva

We introduce a new operad-like structure that we call a reconnectad; the ``input'' of an element of a reconnectad is a finite simple graph, rather than a finite set, and ``compositions'' of elements are performed according to the notion of…

Category Theory · Mathematics 2024-11-28 Vladimir Dotsenko , Adam Keilthy , Denis Lyskov

Recent advances in graph databases (GDBs) have been driving interest in large-scale analytics, yet current systems fail to support higher-order (HO) interactions beyond first-order (one-hop) relations, which are crucial for tasks such as…

Comparing networks is essential for a number of downstream tasks, from clustering to anomaly detection. Despite higher-order interactions being critical for understanding the dynamics of complex systems, traditional approaches for network…

Physics and Society · Physics 2025-11-03 Helcio Felippe , Alec Kirkley , Federico Battiston

Hypergraph offers a framework to depict the multilateral relationships in real-world complex data. Predicting higher-order relationships, i.e hyperedge, becomes a fundamental problem for the full understanding of complicated interactions.…

Social and Information Networks · Computer Science 2021-06-15 Changlin Wan , Muhan Zhang , Wei Hao , Sha Cao , Pan Li , Chi Zhang

Hypergraphs model higher-order relations that drive real-world decisions, from drug prescriptions to recommendations. A central structural signal in such data, beyond what pairwise relations can express, is interaction compositionality:…

Machine Learning · Computer Science 2026-05-19 Kyrie Zhao , Zehong Wang , Tianyi Ma , Fang Wu , Xiangru Tang , Pietro Lio , Sheng Wang , Yanfang Ye

Recent developments in complex systems have witnessed that many real-world scenarios, successfully represented as networks are not always restricted to binary interactions but often include higher-order interactions among the nodes. These…

Adaptation and Self-Organizing Systems · Physics 2022-04-22 Md Sayeed Anwar , Dibakar Ghosh

From social to biological systems, many real-world systems are characterized by higher-order, non-dyadic interactions. Such systems are conveniently described by hypergraphs, where hyperedges encode interactions among an arbitrary number of…

Hypergraphs have been a recent focus of study in mathematical data science as a tool to understand complex networks with high-order connections. One question of particular relevance is how to leverage information carried in hypergraph…

Social and Information Networks · Computer Science 2024-05-09 Enzo Battistella , Sean English , Robert Green , Cliff Joslyn , Evgeniya Lagoda , Van Magnan , Audun Myers , Evan D. Nash , Michael Robinson

One of the key aspects in component-based design is specifying the software architecture that characterizes the topology and the permissible interactions of the components of a system. To achieve well-founded design there is need to address…

Logic in Computer Science · Computer Science 2023-06-22 Maria Pittou , George Rahonis

Groups with complex set intersection relations are a natural way to model a wide array of data, from the formation of social groups to the complex protein interactions which form the basis of biological life. One approach to representing…

Machine Learning · Computer Science 2025-01-15 Sepideh Maleki , Josh Vekhter , Keshav Pingali

We define a $q$-linear path in a hypergraph $H$ as a sequence $(e_1,\ldots,e_L)$ of edges of $H$ such that $|e_i \cap e_{i+1}| \in [\![1,q]\!]$ and $e_i \cap e_j=\varnothing$ if $|i-j|>1$. In this paper, we study the connected components…

Discrete Mathematics · Computer Science 2023-07-14 Florian Galliot , Sylvain Gravier , Isabelle Sivignon

An oriented hypergraph is an oriented incidence structure that extends the concept of a signed graph. We introduce hypergraphic structures and techniques central to the extension of the circuit classification of signed graphs to oriented…

Combinatorics · Mathematics 2016-01-21 Lucas J. Rusnak

A wide variety of complex systems are characterized by interactions of different types involving varying numbers of units. Multiplex hypergraphs serve as a tool to describe such structures, capturing distinct types of higher-order…

Physics and Society · Physics 2024-09-10 Quintino Francesco Lotito , Alberto Montresor , Federico Battiston