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Nucleus instance segmentation in histology images is crucial for a broad spectrum of clinical applications. Current dominant algorithms rely on regression of nuclear proxy maps. Distinguishing nucleus instances from the estimated maps…

Computer Vision and Pattern Recognition · Computer Science 2024-01-25 Zhongyi Shui , Yunlong Zhang , Kai Yao , Chenglu Zhu , Sunyi Zheng , Jingxiong Li , Honglin Li , Yuxuan Sun , Ruizhe Guo , Lin Yang

Few-shot semantic segmentation (FSS) endeavors to segment unseen classes with only a few labeled samples. Current FSS methods are commonly built on the assumption that their training and application scenarios share similar domains, and…

Computer Vision and Pattern Recognition · Computer Science 2024-06-14 Weizhao He , Yang Zhang , Wei Zhuo , Linlin Shen , Jiaqi Yang , Songhe Deng , Liang Sun

The Segment Anything Model (SAM) has demonstrated strong and versatile segmentation capabilities, along with intuitive prompt-based interactions. However, customizing SAM for medical image segmentation requires massive amounts of…

Computer Vision and Pattern Recognition · Computer Science 2025-01-14 Zhonghao Yan , Zijin Yin , Tianyu Lin , Xiangzhu Zeng , Kongming Liang , Zhanyu Ma

The Segment Anything Model (SAM) is a recently proposed prompt-based segmentation model in a generic zero-shot segmentation approach. With the zero-shot segmentation capacity, SAM achieved impressive flexibility and precision on various…

Computer Vision and Pattern Recognition · Computer Science 2023-08-30 Can Cui , Ruining Deng , Quan Liu , Tianyuan Yao , Shunxing Bao , Lucas W. Remedios , Yucheng Tang , Yuankai Huo

Segment Anything Model (SAM), a prompt-driven foundation model for natural image segmentation, has demonstrated impressive zero-shot performance. However, SAM does not work when directly applied to medical image segmentation, since SAM…

Computer Vision and Pattern Recognition · Computer Science 2025-03-25 Bin Xie , Hao Tang , Bin Duan , Dawen Cai , Yan Yan , Gady Agam

The Segment Anything Model (SAM) has demonstrated strong performance in image segmentation of natural scene images. However, its effectiveness diminishes markedly when applied to specific scientific domains, such as Scanning Probe…

Computer Vision and Pattern Recognition · Computer Science 2024-10-17 Yao Shen , Ziwei Wei , Chunmeng Liu , Shuming Wei , Qi Zhao , Kaiyang Zeng , Guangyao Li

Foundation models such as Segment Anything Model 3 (SAM3) enable flexible text-guided medical image segmentation, yet their predictions remain highly sensitive to prompt formulation. Even semantically equivalent descriptions can yield…

Computer Vision and Pattern Recognition · Computer Science 2026-03-09 Yonghuang Wu , Zhenyang Liang , Wenwen Zeng , Xuan Xie , Jinhua Yu

Recently, foundation models trained on massive datasets to adapt to a wide range of tasks have attracted considerable attention and are actively being explored within the computer vision community. Among these, the Segment Anything Model…

Computer Vision and Pattern Recognition · Computer Science 2024-10-14 Hyung-Il Kim , Kimin Yun , Jun-Seok Yun , Yuseok Bae

Recently, Segment Anything Model (SAM) has demonstrated strong generalizability in various instance segmentation tasks. However, its performance is severely dependent on the quality of manual prompts. In addition, the RGB images that…

Computer Vision and Pattern Recognition · Computer Science 2026-02-09 Yihan Shang , Wei Wang , Chao Huang , Xinghui Dong

Cell segmentation is a fundamental task in microscopy image analysis. Several foundation models for cell segmentation have been introduced, virtually all of them are extensions of Segment Anything Model (SAM), improving it for microscopy…

Computer Vision and Pattern Recognition · Computer Science 2026-03-19 Anwai Archit , Constantin Pape

Foundation models such as the recently introduced Segment Anything Model (SAM) have achieved remarkable results in image segmentation tasks. However, these models typically require user interaction through handcrafted prompts such as…

Computer Vision and Pattern Recognition · Computer Science 2024-10-01 Mélanie Gaillochet , Christian Desrosiers , Hervé Lombaert

Extracting small objects from remote sensing imagery plays a vital role in various applications, including urban planning, environmental monitoring, and disaster management. While current research primarily focuses on small object…

Computer Vision and Pattern Recognition · Computer Science 2025-09-04 Chenhao Wang , Yingrui Ji , Yu Meng , Yunjian Zhang , Yao Zhu

The Segment Anything Model (SAM) is a powerful foundation model for image segmentation, showing robust zero-shot generalization through prompt engineering. However, relying on manual prompts is impractical for real-world applications,…

Computer Vision and Pattern Recognition · Computer Science 2025-05-20 Yi Chen , Mu-Young Son , Chuanbo Hua , Joo-Young Kim

Domain-generalized nuclei segmentation refers to the generalizability of models to unseen domains based on knowledge learned from source domains and is challenged by various image conditions, cell types, and stain strategies. Recently, the…

Image and Video Processing · Electrical Eng. & Systems 2025-07-03 Zhenye Lou , Qing Xu , Zekun Jiang , Xiangjian He , Zhen Chen , Yi Wang , Chenxin Li , Maggie M. He , Wenting Duan

In the rapidly evolving field of AI research, foundational models like BERT and GPT have significantly advanced language and vision tasks. The advent of pretrain-prompting models such as ChatGPT and Segmentation Anything Model (SAM) has…

Image and Video Processing · Electrical Eng. & Systems 2024-01-25 Saiyang Na , Yuzhi Guo , Feng Jiang , Hehuan Ma , Junzhou Huang

Cryo-electron microscopy (cryo-EM) remains pivotal in structural biology, yet the task of protein particle picking, integral for 3D protein structure construction, is laden with manual inefficiencies. While recent AI tools such as Topaz and…

Computer Vision and Pattern Recognition · Computer Science 2023-11-29 Fei He , Zhiyuan Yang , Mingyue Gao , Biplab Poudel , Newgin Sam Ebin Sam Dhas , Rajan Gyawali , Ashwin Dhakal , Jianlin Cheng , Dong Xu

Segment Anything Models (SAMs) like SEEM and SAM have demonstrated great potential in learning to segment anything. The core design of SAMs lies with Promptable Segmentation, which takes a handcrafted prompt as input and returns the…

Computer Vision and Pattern Recognition · Computer Science 2024-01-10 Jiaxing Huang , Kai Jiang , Jingyi Zhang , Han Qiu , Lewei Lu , Shijian Lu , Eric Xing

Recent advances in promptable segmentation, such as the Segment Anything Model (SAM), have enabled flexible, high-quality mask generation across a wide range of visual domains. However, SAM and similar models remain fundamentally…

Computer Vision and Pattern Recognition · Computer Science 2025-09-09 Tyler Ward , Abdullah Imran

Foundational models such as the Segment Anything Model (SAM) are gaining traction in medical imaging segmentation, supporting multiple downstream tasks. However, such models are supervised in nature, still relying on large annotated…

Computer Vision and Pattern Recognition · Computer Science 2025-03-07 Aishik Konwer , Zhijian Yang , Erhan Bas , Cao Xiao , Prateek Prasanna , Parminder Bhatia , Taha Kass-Hout

Semantic segmentation is a core task in computer vision. Existing methods are generally divided into two categories: automatic and interactive. Interactive approaches, exemplified by the Segment Anything Model (SAM), have shown promise as…

Computer Vision and Pattern Recognition · Computer Science 2023-12-07 Yimu Pan , Sitao Zhang , Alison D. Gernand , Jeffery A. Goldstein , James Z. Wang
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