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In digital pathology, precise nuclei segmentation is pivotal yet challenged by the diversity of tissue types, staining protocols, and imaging conditions. Recently, the segment anything model (SAM) revealed overwhelming performance in…

Image and Video Processing · Electrical Eng. & Systems 2024-02-27 Zhen Chen , Qing Xu , Xinyu Liu , Yixuan Yuan

Segment Anything Model (SAM) has gained significant recognition in the field of semantic segmentation due to its versatile capabilities and impressive performance. Despite its success, SAM faces two primary limitations: (1) it relies…

Computer Vision and Pattern Recognition · Computer Science 2026-01-21 Yuchen Li , Li Zhang , Youwei Liang , Pengtao Xie

The limited availability of labeled data has driven advancements in semi-supervised learning for medical image segmentation. Modern large-scale models tailored for general segmentation, such as the Segment Anything Model (SAM), have…

Computer Vision and Pattern Recognition · Computer Science 2024-12-19 Kaiwen Huang , Tao Zhou , Huazhu Fu , Yizhe Zhang , Yi Zhou , Chen Gong , Dong Liang

The realm of computer vision has witnessed a paradigm shift with the advent of foundational models, mirroring the transformative influence of large language models in the domain of natural language processing. This paper delves into the…

Computer Vision and Pattern Recognition · Computer Science 2024-06-27 Lv Tang , Peng-Tao Jiang , Hao-Ke Xiao , Bo Li

Is Segment Anything Model 3 (SAM3) capable in segmenting Any Pathology Images? Digital pathology segmentation spans tissue-level and nuclei-level scales, where traditional methods often suffer from high annotation costs and poor…

Computer Vision and Pattern Recognition · Computer Science 2026-05-20 Qiuyu Kong , Shakiba Sharifi , Yiming Wang , Marco Cristani , Zanxi Ruan

Recent advancements in large foundation models have shown promising potential in the medical industry due to their flexible prompting capability. One such model, the Segment Anything Model (SAM), a prompt-driven segmentation model, has…

Computer Vision and Pattern Recognition · Computer Science 2023-08-16 Qi Wu , Yuyao Zhang , Marawan Elbatel

Semi-supervised learning (SSL) has achieved notable progress in medical image segmentation. To achieve effective SSL, a model needs to be able to efficiently learn from limited labeled data and effectively exploiting knowledge from abundant…

Computer Vision and Pattern Recognition · Computer Science 2024-07-09 Juzheng Miao , Cheng Chen , Keli Zhang , Jie Chuai , Quanzheng Li , Pheng-Ann Heng

Pre-trained on a large and diverse dataset, the segment anything model (SAM) is the first promptable foundation model in computer vision aiming at object segmentation tasks. In this work, we evaluate SAM for the task of nuclear instance…

Image and Video Processing · Electrical Eng. & Systems 2024-01-26 Kesi Xu , Lea Goetz , Nasir Rajpoot

The Segment-Anything Model (SAM) is a vision foundation model for segmentation with a prompt-driven framework. SAM generates class-agnostic masks based on user-specified instance-referring prompts. However, adapting SAM for automated…

Computer Vision and Pattern Recognition · Computer Science 2024-11-22 Hussni Mohd Zakir , Eric Tatt Wei Ho

The Segment Anything Model (SAM) is a powerful foundation model that has revolutionised image segmentation. To apply SAM to surgical instrument segmentation, a common approach is to locate precise points or boxes of instruments and then use…

Computer Vision and Pattern Recognition · Computer Science 2023-12-22 Wenxi Yue , Jing Zhang , Kun Hu , Yong Xia , Jiebo Luo , Zhiyong Wang

The Segment Anything Model (SAM) made an eye-catching debut recently and inspired many researchers to explore its potential and limitation in terms of zero-shot generalization capability. As the first promptable foundation model for…

Computer Vision and Pattern Recognition · Computer Science 2023-05-02 Dongjie Cheng , Ziyuan Qin , Zekun Jiang , Shaoting Zhang , Qicheng Lao , Kang Li

In medical image analysis, achieving fast, efficient, and accurate segmentation is essential for automated diagnosis and treatment. Although recent advancements in deep learning have significantly improved segmentation accuracy, current…

Computer Vision and Pattern Recognition · Computer Science 2024-12-02 Zhi Li , Kai Zhao , Yaqi Wang , Shuai Wang

Segmentation is central to clinical diagnosis and monitoring, yet the reliability of modern foundation models in medical imaging still depends on the availability of precise prompts. The Segment Anything Model (SAM) offers powerful…

Purpose: Recent developments in computational pathology have been driven by advances in Vision Foundation Models, particularly the Segment Anything Model (SAM). This model facilitates nuclei segmentation through two primary methods:…

Computer Vision and Pattern Recognition · Computer Science 2025-08-22 Xueyuan Li , Can Cui , Ruining Deng , Yucheng Tang , Quan Liu , Tianyuan Yao , Shunxing Bao , Naweed Chowdhury , Haichun Yang , Yuankai Huo

Deep learning based methods often suffer from performance degradation caused by domain shift. In recent years, many sophisticated network structures have been designed to tackle this problem. However, the advent of large model trained on…

Computer Vision and Pattern Recognition · Computer Science 2024-09-20 Zhikai Wei , Wenhui Dong , Peilin Zhou , Yuliang Gu , Zhou Zhao , Yongchao Xu

Atom-probe tomography (APT) facilitates nano- and atomic-scale characterization and analysis of microstructural features. Specifically, APT is well suited to study the interfacial properties of granular or heterophase systems.…

The Segment Anything Model (SAM) is a deep neural network foundational model designed to perform instance segmentation which has gained significant popularity given its zero-shot segmentation ability. SAM operates by generating masks based…

Computer Vision and Pattern Recognition · Computer Science 2024-04-19 Yona Falinie A. Gaus , Neelanjan Bhowmik , Brian K. S. Isaac-Medina , Toby P. Breckon

Semantic segmentations of pathological entities have crucial clinical value in computational pathology workflows. Foundation models, such as the Segment Anything Model (SAM), have been recently proposed for universal use in segmentation…

Image and Video Processing · Electrical Eng. & Systems 2023-07-20 Jingwei Zhang , Ke Ma , Saarthak Kapse , Joel Saltz , Maria Vakalopoulou , Prateek Prasanna , Dimitris Samaras

Leveraging the extensive training data from SA-1B, the Segment Anything Model (SAM) demonstrates remarkable generalization and zero-shot capabilities. However, as a category-agnostic instance segmentation method, SAM heavily relies on prior…

Computer Vision and Pattern Recognition · Computer Science 2023-11-30 Keyan Chen , Chenyang Liu , Hao Chen , Haotian Zhang , Wenyuan Li , Zhengxia Zou , Zhenwei Shi

Adapting large pre-trained foundation models, e.g., SAM, for medical image segmentation remains a significant challenge. A crucial step involves the formulation of a series of specialized prompts that incorporate specific clinical…

Computer Vision and Pattern Recognition · Computer Science 2024-09-04 Xiuqi Zheng , Yuhang Zhang , Haoran Zhang , Hongrui Liang , Xueqi Bao , Zhuqing Jiang , Qicheng Lao