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The rapid scaling of large computational models has led to a critical increase in energy and compute costs. Inspired by biological systems where structure and function emerge from low-energy configurations, we introduce StructuredDNA, a…

Machine Learning · Computer Science 2025-12-11 Mustapha Hamdi

The current landscape of AI for Science (AI4S) is predominantly anchored in large-scale textual corpora, where generative AI systems excel at hypothesis generation, literature search, and multi-modal reasoning. However, a critical…

Scientific theory shift in AI agents requires more than fitting equations to data. An artificial scientific agent must detect whether an existing representational framework remains transportable into a new regime, or whether its language…

Artificial Intelligence · Computer Science 2026-05-15 David N. Olivieri , Roque J. Hernández

With the continue development of Convolutional Neural Networks (CNNs), there is a growing concern regarding representations that they encode internally. Analyzing these internal representations is referred to as model interpretation. While…

Computer Vision and Pattern Recognition · Computer Science 2023-05-18 Hamed Behzadi-Khormouji , José Oramas

High-stakes decision systems increasingly require structured justification, traceability, and auditability to ensure accountability and regulatory compliance. Formal arguments commonly used in the certification of safety-critical systems…

Artificial Intelligence · Computer Science 2026-04-07 Mahyar T. Moghaddam

This dissertation addresses achieving causal interpretability in Deep Learning for Software Engineering (DL4SE). While Neural Code Models (NCMs) show strong performance in automating software tasks, their lack of transparency in causal…

Software Engineering · Computer Science 2025-05-22 David N. Palacio

Structured reasoning over natural language inputs remains a core challenge in artificial intelligence, as it requires bridging the gap between unstructured linguistic expressions and formal logical representations. In this paper, we propose…

Artificial Intelligence · Computer Science 2025-07-14 Keying Yang , Hao Wang , Kai Yang

Automated reasoning is critical in domains such as law and governance, where verifying claims against facts in documents requires both accuracy and interpretability. Recent work adopts structured reasoning pipelines that translate natural…

Artificial Intelligence · Computer Science 2026-02-17 Rizky Ramadhana Putra , Raihan Sultan Pasha Basuki , Yutong Cheng , Peng Gao

Reasoning on large and complex real-world models is a computationally difficult task, yet one that is required for effective use of many AI applications. A plethora of inference algorithms have been developed that work well on specific…

Artificial Intelligence · Computer Science 2016-06-13 Avi Pfeffer , Brian Ruttenberg , William Kretschmer

Intrusion detection systems (IDSs) for 5G networks must handle complex, high-volume traffic. Although opaque "black-box" models can achieve high accuracy, their lack of transparency hinders trust and effective operational response. We…

Cryptography and Security · Computer Science 2026-04-21 Saeid Sheikhi , Panos Kostakos , Lauri Loven

Artificial intelligence (AI) has demonstrated strong potential in clinical diagnostics, often achieving accuracy comparable to or exceeding that of human experts. A key challenge, however, is that AI reasoning frequently diverges from…

Artificial Intelligence · Computer Science 2026-05-25 Belona Sonna , Alban Grastien

This paper presents ExplainableFold, an explainable AI framework for protein structure prediction. Despite the success of AI-based methods such as AlphaFold in this field, the underlying reasons for their predictions remain unclear due to…

Artificial Intelligence · Computer Science 2023-06-12 Juntao Tan , Yongfeng Zhang

Language models based on the Transformer architecture achieve excellent results in many language-related tasks, such as text classification or sentiment analysis. However, despite the architecture of these models being well-defined, little…

Computation and Language · Computer Science 2025-04-14 Miguel López-Otal , Jorge Gracia , Jordi Bernad , Carlos Bobed , Lucía Pitarch-Ballesteros , Emma Anglés-Herrero

Transformer-decoder language models are a core innovation in text based generative artificial intelligence. These models are being deployed as general-purpose intelligence systems in many applications. Central to their utility is the…

Artificial Intelligence · Computer Science 2025-05-09 John Hawkins

Recent advances in methods focused on the grounding problem have resulted in techniques that can be used to construct a symbolic language associated with a specific domain. Inspired by how humans communicate complex ideas through language,…

Artificial Intelligence · Computer Science 2020-08-06 Alberto Santamaria-Pang , James Kubricht , Aritra Chowdhury , Chitresh Bhushan , Peter Tu

Despite the success of Large Vision--Language Models (LVLMs), most existing architectures suffer from a representation bottleneck: they rely on static, instruction-agnostic vision encoders whose visual representations are utilized in an…

Computer Vision and Pattern Recognition · Computer Science 2026-03-10 Hanpeng Liu , Yaqian Li , Zidan Wang , Shuoxi Zhang , Zihao Bo , Rinyoichi Takezoe , Kaiwen Long , Kun He

In the wake of the swift evolution of technologies such as the Internet of Things (IoT), the global data landscape undergoes an exponential surge, propelling DNA storage into the spotlight as a prospective medium for contemporary cloud…

Machine Learning · Computer Science 2024-09-20 Wenfeng Wu , Luping Xiang , Qiang Liu , Kun Yang

Motivation: The scalable identification of bioactive compounds is essential for contemporary drug discovery. This process faces a key trade-off: structural screening offers scalability but lacks biological context, whereas high-content…

Quantitative Methods · Quantitative Biology 2026-03-17 Xiaoqing Lian , Pengsen Ma , Tengfeng Ma , Zhonghao Ren , Xibao Cai , Zhixiang Cheng , Bosheng Song , He Wang , Xiang Pan , Yangyang Chen , Sisi Yuan , Chen Lin

Existing multimodal document question-answering (QA) systems predominantly rely on flat semantic retrieval, representing documents as a set of disconnected text chunks and largely neglecting their intrinsic hierarchical and relational…

Information Retrieval · Computer Science 2026-01-28 ShunLiang Fu , Yanxin Zhang , Yixin Xiang , Xiaoyu Du , Jinhui Tang

When the system is linear, why should learning be nonlinear? Linear dynamical systems, the analytical backbone of control theory, signal processing and circuit analysis, have exact closed-form solutions via the state transition matrix. Yet…

Machine Learning · Computer Science 2026-03-31 Shafayeth Jamil , Rehan Kapadia