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The proliferation of deepfake technologies poses urgent challenges and serious risks to digital integrity, particularly within critical sectors such as forensics, journalism, and the legal system. While existing detection systems have made…

Computer Vision and Pattern Recognition · Computer Science 2025-08-12 Shahroz Tariq , Simon S. Woo , Priyanka Singh , Irena Irmalasari , Saakshi Gupta , Dev Gupta

The exponential growth of scientific knowledge has created significant barriers to cross-disciplinary knowledge discovery, synthesis and research collaboration. In response to this challenge, we present BioSage, a novel compound AI…

Tandem duplication is the process of inserting a copy of a segment of DNA adjacent to the original position. Motivated by applications that store data in living organisms, Jain et al. (2017) proposed the study of codes that correct tandem…

Information Theory · Computer Science 2018-01-09 Yeow Meng Chee , Johan Chrisnata , Han Mao Kiah , Tuan Thanh Nguyen

Current biological AI models lack interpretability -- their internal representations do not correspond to biological relationships that researchers can examine. Understanding gene regulation requires models whose learned structure can be…

Machine Learning · Computer Science 2026-03-17 Nobuyuki Ota

DNA language models are increasingly used to represent genomic sequence, yet their effectiveness depends critically on how raw nucleotides are converted into model inputs. Unlike natural language, DNA offers no canonical boundaries, making…

Genomics · Quantitative Biology 2026-05-21 Taewon Kim , Jihwan Shin , Hyomin Kim , Youngmok Jung , Jonghoon Lee , Won-Chul Lee , Sungsoo Ahn , Insu Han

As artificial intelligence systems increasingly inform high-stakes decisions across sectors, transparency has become foundational to responsible and trustworthy AI implementation. Leveraging our role as a leading institute in advancing AI…

Machine Learning · Computer Science 2025-08-01 Dhanesh Ramachandram , Himanshu Joshi , Judy Zhu , Dhari Gandhi , Lucas Hartman , Ananya Raval

Recent genomic foundation models largely adopt large language model architectures that treat DNA as a one-dimensional token sequence. However, exhaustive sequential reading is structurally misaligned with sparse and discontinuous genomic…

Computer Vision and Pattern Recognition · Computer Science 2026-02-03 Hongxin Xiang , Pengsen Ma , Yunkang Cao , Di Yu , Haowen Chen , Xinyu Yang , Xiangxiang Zeng

Ever since deoxyribonucleic acid (DNA) was considered as a next-generation data-storage medium, lots of research efforts have been made to correct errors occurred during the synthesis, storage, and sequencing processes using error…

Information Theory · Computer Science 2023-06-14 Jaeho Jeong , Hosung Park , Hee-Youl Kwak , Jong-Seon No , Hahyeon Jeon , Jeong Wook Lee , Jae-Won Kim

Intelligent anomaly detection in dynamic visual environments requires reconciling real-time performance with semantic interpretability. Conventional approaches address only fragments of this challenge. Reconstruction-based models capture…

Computer Vision and Pattern Recognition · Computer Science 2026-01-19 Tayyab Rehman , Giovanni De Gasperis , Aly Shmahell

With the rapid advancement of tool-use capabilities in Large Language Models (LLMs), Retrieval-Augmented Generation (RAG) is shifting from static, one-shot retrieval toward autonomous, multi-turn evidence acquisition. However, existing…

Artificial Intelligence · Computer Science 2026-02-13 Zhanli Li , Huiwen Tian , Lvzhou Luo , Yixuan Cao , Ping Luo

Predicting gene function from its DNA sequence is a fundamental challenge in biology. Many deep learning models have been proposed to embed DNA sequences and predict their enzymatic function, leveraging information in public databases…

Biological sequences encode fundamental instructions for the building blocks of life, in the form of DNA, RNA, and proteins. Modeling these sequences is key to understand disease mechanisms and is an active research area in computational…

Shannon's information theory deliberately excludes message semantics. This paper develops a rigorous framework for semantic communication that integrates formal proof systems with Shannon-theoretic tools. We introduce an axiomatic…

Logic in Computer Science · Computer Science 2026-04-21 Jianfeng Xu

The semantically disentangled latent subspace in GAN provides rich interpretable controls in image generation. This paper includes two contributions on semantic latent subspace analysis in the scenario of face generation using StyleGAN2.…

Computer Vision and Pattern Recognition · Computer Science 2022-01-25 Bo Li , Qiulin Wang , Jiquan Pei , Yu Yang , Xiangyang Ji

The flexibility and complexity of IPv6 extension headers allow attackers to create covert channels or bypass security mechanisms, leading to potential data breaches or system compromises. The mature development of machine learning has…

Recent works on form understanding mostly employ multimodal transformers or large-scale pre-trained language models. These models need ample data for pre-training. In contrast, humans can usually identify key-value pairings from a form only…

Computation and Language · Computer Science 2023-05-09 Bhanu Prakash Voutharoja , Lizhen Qu , Fatemeh Shiri

Neuro-symbolic methods integrate neural architectures, knowledge representation and reasoning. However, they have been struggling at both dealing with the intrinsic uncertainty of the observations and scaling to real-world applications.…

Artificial Intelligence · Computer Science 2025-01-16 Giuseppe Marra , Michelangelo Diligenti , Francesco Giannini

Semantic information in embodied AI is inherently multi-source and multi-stage, making it challenging to fully leverage for achieving stable perception-to-action loops in real-world environments. Early studies have combined manual…

Computer Vision and Pattern Recognition · Computer Science 2026-01-15 Shuai Chen , Hao Chen , Yuanchen Bei , Tianyang Zhao , Zhibo Zhou , Feiran Huang

This work proposes a markovian memoryless model for the DNA that simplifies enormously the complexity of it. We encode nucleotide sequences into symbolic sequences, called words, from which we establish meaningful length of words and group…

Biological Physics · Physics 2015-10-09 Shambhavi Srivastava , Murilo S. Baptista

Robust machine learning for regulatory genomics is studied under biologically and technically induced distribution shifts. Deep convolutional and attention based models achieve strong in distribution performance on DNA regulatory sequence…

Genomics · Quantitative Biology 2026-02-20 Yiyao Yang
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