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Simulating dementia patients with large language models (LLMs) is challenging due to the need to jointly model cognitive impairment, emotional dynamics, and nonverbal behaviors over long conversations. We present DemMA, an expert-guided…

Multiagent Systems · Computer Science 2026-01-13 Yutong Song , Jiang Wu , Kazi Sharif , Honghui Xu , Nikil Dutt , Amir Rahmani

Dementia is a growing problem as our society ages, and detection methods are often invasive and expensive. Recent deep-learning techniques can offer a faster diagnosis and have shown promising results. However, they require large amounts of…

Computation and Language · Computer Science 2022-07-19 Anna Hlédiková , Dominika Woszczyk , Alican Akman , Soteris Demetriou , Björn Schuller

Deep learning systems often struggle with processing long sequences, where computational complexity can become a bottleneck. Current methods for automated dementia detection using speech frequently rely on static, time-agnostic features or…

Sound · Computer Science 2025-10-02 Chukwuemeka Ugwu , Oluwafemi Oyeleke

A wide variety of agentic AI applications - ranging from cognitive assistants for dementia patients to robotics - demand a robust memory system grounded in reality. In this paper, we propose such a memory system consisting of three…

Artificial Intelligence · Computer Science 2025-05-13 Felix Ocker , Jörg Deigmöller , Pavel Smirnov , Julian Eggert

This study explores a novel approach to advancing dementia care by integrating socially assistive robotics, reinforcement learning (RL), large language models (LLMs), and clinical domain expertise within a simulated environment. This…

Artificial Intelligence · Computer Science 2025-01-30 Fengpei Yuan , Nehal Hasnaeen , Ran Zhang , Bryce Bible , Joseph Riley Taylor , Hairong Qi , Fenghui Yao , Xiaopeng Zhao

Memory-Augmented Generation (MAG) extends Large Language Models with external memory to support long-context reasoning, but existing approaches largely rely on semantic similarity over monolithic memory stores, entangling temporal, causal,…

Artificial Intelligence · Computer Science 2026-04-17 Dongming Jiang , Yi Li , Guanpeng Li , Bingzhe Li

Early detection of dementia is critical for timely medical intervention and improved patient outcomes. Neuropsychological tests are widely used for cognitive assessment but have traditionally relied on manual scoring. Automatic dementia…

Machine Learning · Computer Science 2025-07-15 Liming Wang , Saurabhchand Bhati , Cody Karjadi , Rhoda Au , James Glass

Alzheimer's disease (AD) constitutes a complex neurocognitive disease and is the main cause of dementia. Although many studies have been proposed targeting at diagnosing dementia through spontaneous speech, there are still limitations.…

Computation and Language · Computer Science 2023-08-24 Loukas Ilias , Dimitris Askounis

Dementia is a group of irreversible, chronic, and progressive neurodegenerative disorders resulting in impaired memory, communication, and thought processes. In recent years, clinical research advances in brain aging have focused on the…

Computation and Language · Computer Science 2021-02-25 Swati Padhee , Anurag Illendula , Megan Sadler , Valerie L. Shalin , Tanvi Banerjee , Krishnaprasad Thirunarayan , William L. Romine

Clinical natural language processing (NLP) is increasingly in demand in both clinical research and operational practice. However, most of the state-of-the-art solutions are transformers-based and require high computational resources,…

Computation and Language · Computer Science 2025-04-18 Jianlin Shi , Qiwei Gan , Elizabeth Hanchrow , Annie Bowles , John Stanley , Adam P. Bress , Jordana B. Cohen , Patrick R. Alba

Large language models (LLMs) have significantly advanced the field of natural language generation. However, they frequently generate unverified outputs, which compromises their reliability in critical applications. In this study, we propose…

Computation and Language · Computer Science 2025-02-18 Alexandru Lecu , Adrian Groza , Lezan Hawizy

Dementia is a neurodegenerative disorder that causes cognitive decline and affects more than 50 million people worldwide. Dementia is under-diagnosed by healthcare professionals - only one in four people who suffer from dementia are…

Alzheimer's disease (AD) is a progressive neurodegenerative disorder and the leading cause of dementia, affecting memory, reasoning, communication, and daily functioning. Early diagnosis is particularly important, as timely intervention may…

Sound · Computer Science 2026-05-26 Loukas Ilias , Dimitris Askounis

The differential diagnosis of neurodegenerative dementias is a challenging clinical task, mainly because of the overlap in symptom presentation and the similarity of patterns observed in structural neuroimaging. To improve diagnostic…

Machine Learning · Computer Science 2025-05-27 Andrew Zamai , Nathanael Fijalkow , Boris Mansencal , Laurent Simon , Eloi Navet , Pierrick Coupe

Developing artificial intelligence based assistive systems to aid Persons with Dementia (PwD) requires large amounts of training data. However, data collection poses ethical, legal, economic, and logistic issues. Synthetic data generation…

Artificial Intelligence · Computer Science 2021-07-13 Muhammad Salman Shaukat , Bjarne Christian Hiller , Sebastian Bader , Thomas Kirste

Retrieval-Augmented Generation (RAG) is widely employed to mitigate risks such as hallucinations and knowledge obsolescence in medical question answering, yet its predominantly single-round, static retrieval paradigm misaligns with the…

Computation and Language · Computer Science 2026-05-19 Yongfeng Huang , Ruiying Chen , James Cheng

Text-to-image models generate highly realistic images based on natural language descriptions and millions of users use them to create and share images online. While it is expected that such models can align input text and generated image in…

Machine Learning · Computer Science 2025-08-14 Mansi , Anastasios Lepipas , Dominika Woszczyk , Yiying Guan , Soteris Demetriou

Based on official estimates, 50 million people worldwide are affected by dementia, and this number increases by 10 million new patients every year. Without a cure, clinical prognostication and early intervention represent the most effective…

Computation and Language · Computer Science 2024-09-06 Francisco de Arriba-Pérez , Silvia García-Méndez

Data limitation is one of the most common issues in training machine learning classifiers for medical applications. Due to ethical concerns and data privacy, the number of people that can be recruited to such experiments is generally…

Audio and Speech Processing · Electrical Eng. & Systems 2020-04-14 Bahman Mirheidari , Yilin Pan , Daniel Blackburn , Ronan O'Malley , Traci Walker , Annalena Venneri , Markus Reuber , Heidi Christensen

AI agents that interact with users across multiple sessions require persistent long-term memory to maintain coherent, personalized behavior. Current approaches either rely on flat retrieval-augmented generation (RAG), which loses structural…

Artificial Intelligence · Computer Science 2026-05-14 Swarna Kamal Paul , Shubhendu Sharma , Nitin Sareen
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