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Related papers: DEMENTIA-PLAN: An Agent-Based Framework for Multi-…

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With people living longer than ever, the number of cases with dementia such as Alzheimer's disease increases steadily. It affects more than 46 million people worldwide, and it is estimated that in 2050 more than 100 million will be…

Multimedia · Computer Science 2021-01-20 Mariona Caros , Maite Garolera , Petia Radeva , Xavier Giro-i-Nieto

Depression poses significant challenges to patients and healthcare organizations, necessitating efficient assessment methods. Existing paradigms typically focus on a patient-doctor way that overlooks multi-role interactions, such as family…

Human-Computer Interaction · Computer Science 2026-03-10 Zhiyuan Zhou , Jilong Liu , Sanwang Wang , Shijie Hao , Yanrong Guo , Richang Hong

Alzheimer's Disease is the most common cause of dementia. Accurate diagnosis and prognosis of this disease are essential to design an appropriate treatment plan, increasing the life expectancy of the patient. Intense research has been…

Image and Video Processing · Electrical Eng. & Systems 2023-01-05 Huy-Dung Nguyen , Michaël Clément , Boris Mansencal , Pierrick Coupé

Deep learning (DL) techniques involving fine-tuning large numbers of model parameters have delivered impressive performance on the task of discriminating between language produced by cognitively healthy individuals, and those with…

Computation and Language · Computer Science 2022-03-28 Changye Li , David Knopman , Weizhe Xu , Trevor Cohen , Serguei Pakhomov

Dementia is associated with language disorders which impede communication. Here, we automatically learn linguistic disorder patterns by making use of a moderately-sized pre-trained language model and forcing it to focus on reformulated…

Computation and Language · Computer Science 2023-10-17 Dimitris Gkoumas , Matthew Purver , Maria Liakata

Dementia is associated with various cognitive impairments and typically manifests only after significant progression, making intervention at this stage often ineffective. To address this issue, the Prediction and Recognition of Cognitive…

Dementia affects cognitive functions of adults, including memory, language, and behaviour. Standard diagnostic biomarkers such as MRI are costly, whilst neuropsychological tests suffer from sensitivity issues in detecting dementia onset.…

Computation and Language · Computer Science 2023-12-27 Dimitris Gkoumas , Bo Wang , Adam Tsakalidis , Maria Wolters , Arkaitz Zubiaga , Matthew Purver , Maria Liakata

Deep research agents (DRAs) integrate LLM reasoning with external tools. Memory systems enable DRAs to leverage historical experiences, which are essential for efficient reasoning and autonomous evolution. Existing methods rely on…

Artificial Intelligence · Computer Science 2026-04-21 Jingyang Qiao , Weicheng Meng , Yu Cheng , Zhihang Lin , Zhizhong Zhang , Xin Tan , Jingyu Gong , Kun Shao , Yuan Xie

Multimodal Retrieval-Augmented Generation (mRAG) has emerged as a promising solution to address the temporal limitations of Multimodal Large Language Models (MLLMs) in real-world scenarios like news analysis and trending topics. However,…

Artificial Intelligence · Computer Science 2025-08-13 Yuechen Wang , Yuming Qiao , Dan Meng , Jun Yang , Haonan Lu , Zhenyu Yang , Xudong Zhang

Recent search-augmented LLMs trained with reinforcement learning (RL) can interleave searching and reasoning for multi-hop reasoning tasks. However, they face two critical failure modes as the accumulating context becomes flooded with both…

Computation and Language · Computer Science 2026-01-14 Kangcheng Luo , Tinglang Wu , Yansong Feng

Motivation: The importance of clinical data in understanding the pathophysiology of complex disorders has prompted the launch of multiple initiatives designed to generate patient-level data from various modalities. While these studies can…

Alzheimer's disease (AD) is an irreversible brain disease that can dramatically reduce quality of life, most commonly manifesting in older adults and eventually leading to the need for full-time care. Early detection is fundamental to…

Computation and Language · Computer Science 2019-06-14 Flavio Di Palo , Natalie Parde

Large Language Models (LLMs) lack persistent memory for long-term personalized conversations. Existing graph-based memory systems suffer from information dilution, absent provenance tracking, and uniform retrieval that ignores query…

Computation and Language · Computer Science 2026-05-05 Hung Pham Van , Nguyen Manh Hieu , Khang Pham Tran Tuan , Nam Le Hai , Linh Ngo Van , Nguyen Thi Ngoc Diep , Trung Le

Over half of US adults with Alzheimer disease and related dementias remain undiagnosed, and speech-based screening offers a scalable detection approach. We compared large language model adaptation strategies for dementia detection using the…

Alzheimer's Disease (AD) is an irreversible neurodegenerative disease affecting 50 million people worldwide. Low-cost, accurate identification of key markers of AD is crucial for timely diagnosis and intervention. Language impairment is one…

Computation and Language · Computer Science 2025-05-27 Tingyu Mo , Jacqueline C. K. Lam , Victor O. K. Li , Lawrence Y. L. Cheung

Alzheimer's dementia (AD) affects memory, thinking, and language, deteriorating person's life. An early diagnosis is very important as it enables the person to receive medical help and ensure quality of life. Therefore, leveraging…

Machine Learning · Computer Science 2023-04-06 Michail Chatzianastasis , Loukas Ilias , Dimitris Askounis , Michalis Vazirgiannis

Alzheimer's disease (AD) is a progressive neurological disorder, meaning that the symptoms develop gradually throughout the years. It is also the main cause of dementia, which affects memory, thinking skills, and mental abilities. Nowadays,…

Computation and Language · Computer Science 2022-11-09 Loukas Ilias , Dimitris Askounis , John Psarras

Effective dementia caregiving requires training and adaptive communication, but assistive AI and robotics are constrained by a lack of context-rich, privacy-sensitive data on how people living with Alzheimer's disease and related dementias…

Human-Computer Interaction · Computer Science 2026-04-01 Kruthika Gangaraju , Shu-Fen Wung , Kevin Berner , Jing Wang , Fengpei Yuan

Memory emerges as the core module in the Large Language Model (LLM)-based agents for long-horizon complex tasks (e.g., multi-turn dialogue, game playing, scientific discovery), where memory can enable knowledge accumulation, iterative…

Dementia, a progressive neurodegenerative disorder, affects memory, reasoning, and daily functioning, creating challenges for individuals and healthcare systems. Early detection is crucial for timely interventions that may slow disease…

Neurons and Cognition · Quantitative Biology 2025-03-04 Sahar Sinene Mehdoui , Abdelhamid Bouzid , Daniel Sierra-Sosa , Adel Elmaghraby