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Breast cancer is one of the leading causes of female mortality in the world. This can be reduced when diagnoses are performed at the early stages of progression. Further, the efficiency of the process can be significantly improved with…

Image and Video Processing · Electrical Eng. & Systems 2022-02-15 Aravind Ravi

Statistical inference of the fundamental parameters of supersymmetric theories is a challenging and active endeavor. Several sophisticated algorithms have been employed to this end. While Markov-Chain Monte Carlo (MCMC) and nested sampling…

High Energy Physics - Phenomenology · Physics 2015-03-17 F. Feroz , K. Cranmer , M. Hobson , R. Ruiz de Austri , R. Trotta

Person image generation aims to perform non-rigid deformation on source images, which generally requires unaligned data pairs for training. Recently, self-supervised methods express great prospects in this task by merging the disentangled…

Computer Vision and Pattern Recognition · Computer Science 2022-12-15 Zijian Wang , Xingqun Qi , Kun Yuan , Muyi Sun

Understanding protein dynamics are essential for deciphering protein functional mechanisms and developing molecular therapies. However, the complex high-dimensional dynamics and interatomic interactions of biological processes pose…

Quantitative Methods · Quantitative Biology 2025-05-15 Tiexin Qin , Mengxu Zhu , Chunyang Li , Terry Lyons , Hong Yan , Haoliang Li

We propose a semi-supervised network for wide-angle portraits correction. Wide-angle images often suffer from skew and distortion affected by perspective distortion, especially noticeable at the face regions. Previous deep learning based…

Computer Vision and Pattern Recognition · Computer Science 2022-04-05 Fushun Zhu , Shan Zhao , Peng Wang , Hao Wang , Hua Yan , Shuaicheng Liu

Accurate RNA structure modeling remains difficult because RNA backbones are highly flexible, non-canonical interactions are prevalent, and experimentally determined 3D structures are comparatively scarce. We introduce \emph{RiboSphere}, a…

Machine Learning · Computer Science 2026-03-23 Zhou Zhang , Hanqun Cao , Cheng Tan , Fang Wu , Pheng Ann Heng , Tianfan Fu

Predicting the secondary structure of RNA is a core challenge in computational biology, essential for understanding molecular function and designing novel therapeutics. The field has evolved from foundational but accuracy-limited…

Biomolecules · Quantitative Biology 2026-05-20 Giuseppe Sacco , Giovanni Bussi , Guido Sanguinetti

Clustering is widely used in unsupervised learning method that deals with unlabeled data. Deep clustering has become a popular study area that relates clustering with Deep Neural Network (DNN) architecture. Deep clustering method…

Machine Learning · Computer Science 2020-07-14 Abu Quwsar Ohi , M. F. Mridha , Farisa Benta Safir , Md. Abdul Hamid , Muhammad Mostafa Monowar

Crowd counting is a challenging task due to the heavy occlusions, scales, and density variations. Existing methods handle these challenges effectively while ignoring low-resolution (LR) circumstances. The LR circumstances weaken the…

Computer Vision and Pattern Recognition · Computer Science 2023-03-14 Jiahao Xie , Wei Xu , Dingkang Liang , Zhanyu Ma , Kongming Liang , Weidong Liu , Rui Wang , Ling Jin

Super-resolution ultrasound (SRUS) imaging through localising and tracking sparse microbubbles has been shown to reveal microvascular structure and flow beyond the wave diffraction limit. Most SRUS studies use standard delay and sum (DAS)…

RNA sequencing (RNA-seq) is the conventional genome-scale approach used to capture the expression levels of all detectable genes in a biological sample. This is now regularly used for population-based studies designed to identify genetic…

Genomics · Quantitative Biology 2026-05-25 Christopher Thron , Farhad Jafari

Spectral clustering has shown a superior performance in analyzing the cluster structure. However, its computational complexity limits its application in analyzing large-scale data. To address this problem, many low-rank matrix approximating…

Machine Learning · Computer Science 2020-07-23 Djallel Bouneffouf

When nanoparticles (NPs) are introduced into a biological solution, layers of biomolecules form on their surface, creating a corona. Understanding how the structure of the protein evolves into the corona is essential for evaluating the…

Supervised deep learning approaches can artificially increase the resolution of microscopy images by learning a mapping between two image resolutions or modalities. However, such methods often require a large set of hard-to-get…

Image and Video Processing · Electrical Eng. & Systems 2024-11-20 Marzieh Gheisari , Auguste Genovesio

In several application domains, high-dimensional observations are collected and then analysed in search for naturally occurring data clusters which might provide further insights about the nature of the problem. In this paper we describe a…

Machine Learning · Statistics 2012-03-07 Brian McWilliams , Giovanni Montana

Breast ultrasound (US) is an effective imaging modality for breast cancer detec-tion and diagnosis. The structural characteristics of breast lesion play an im-portant role in Computer-Aided Diagnosis (CAD). In this paper, a novel…

Image and Video Processing · Electrical Eng. & Systems 2020-06-16 Erlei Zhang , Zi Yang , Stephen Seiler , Mingli Chen , Weiguo Lu , Xuejun Gu

Nuclear magnetic resonance (NMR) spectroscopy is one of the leading techniques for protein studies. The method features a number of properties, allowing to explain macromolecular interactions mechanistically and resolve structures with…

Quantitative Methods · Quantitative Biology 2018-08-03 Piotr Klukowski , Adam Gonczarek

Semi-supervised clustering is an very important topic in machine learning and computer vision. The key challenge of this problem is how to learn a metric, such that the instances sharing the same label are more likely close to each other on…

Machine Learning · Computer Science 2015-01-27 Gang Chen

We present an algorithm for multi-scale tumor (chimeric cell) detection in high resolution slide scans. The broad range of tumor sizes in our dataset pose a challenge for current Convolutional Neural Networks (CNN) which often fail when…

Computer Vision and Pattern Recognition · Computer Science 2021-04-27 Qingchao Zhang , Coy D. Heldermon , Corey Toler-Franklin

Pansharpening is a crucial task in remote sensing, enabling the generation of high-resolution multispectral images by fusing low-resolution multispectral data with high-resolution panchromatic images. This paper provides a comprehensive…

Image and Video Processing · Electrical Eng. & Systems 2024-12-09 Mahek Kantharia , Neeraj Badal , Zankhana Shah