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Anatomy evaluation is crucial for understanding the physiological state, diagnosing abnormalities, and guiding medical interventions. Statistical shape modeling (SSM) is vital in this process. By enabling the extraction of quantitative…

Computer Vision and Pattern Recognition · Computer Science 2025-02-12 Krithika Iyer , Mokshagna Sai Teja Karanam , Shireen Elhabian

Modern technology for producing extremely bright and coherent X-ray laser pulses provides the possibility to acquire a large number of diffraction patterns from individual biological nanoparticles, including proteins, viruses, and DNA.…

Methodology · Statistics 2018-07-11 Stefan Engblom , Carl Nettelblad , Jing Liu

Given a union of non-linear manifolds, non-linear subspace clustering or manifold clustering aims to cluster data points based on manifold structures and also learn to parameterize each manifold as a linear subspace in a feature space. Deep…

Machine Learning · Computer Science 2022-01-26 Zengyi Li , Yubei Chen , Yann LeCun , Friedrich T. Sommer

Several methods for triclustering three-dimensional data require the cluster size or the number of clusters in each dimension to be specified. To address this issue, the Multi-Slice Clustering (MSC) for 3-order tensor finds signal slices…

Machine Learning · Computer Science 2023-03-27 Dina Faneva Andriantsiory , Joseph Ben Geloun , Mustapha Lebbah

There are several cutting edge applications needing PCA methods for data on tori and we propose a novel torus-PCA method with important properties that can be generally applied. There are two existing general methods: tangent space PCA and…

Methodology · Statistics 2015-11-17 Benjamin Eltzner , Stephan Huckemann , Kanti V. Mardia

In recent years, the advances in single-cell RNA-seq techniques have enabled us to perform large-scale transcriptomic profiling at single-cell resolution in a high-throughput manner. Unsupervised learning such as data clustering has become…

Genomics · Quantitative Biology 2020-01-07 Shixiong Zhang , Xiangtao Li , Qiuzhen Lin , Ka-Chun Wong

Recently, convolutional neural networks (CNN) have been successfully applied to many remote sensing problems. However, deep learning techniques for multi-image super-resolution from multitemporal unregistered imagery have received little…

Image and Video Processing · Electrical Eng. & Systems 2020-01-16 Andrea Bordone Molini , Diego Valsesia , Giulia Fracastoro , Enrico Magli

In mammalian cells, repair centers for DNA double-strand breaks (DSBs) have been identified. However, previous researches predominantly rely on methods that induce specific DSBs by cutting particular DNA sequences. The clustering and its…

Biological Physics · Physics 2024-10-07 Junyi Chen , Wenzong Ma , Yuqi Ma , Gen Yang

Segmentation of white matter lesions and deep grey matter structures is an important task in the quantification of magnetic resonance imaging in multiple sclerosis. In this paper we explore segmentation solutions based on convolutional…

Subspace segmentation or subspace learning is a challenging and complicated task in machine learning. This paper builds a primary frame and solid theoretical bases for the minimal subspace segmentation (MSS) of finite samples. Existence and…

Machine Learning · Computer Science 2019-09-10 Zhenyue Zhang , Yuqing Xia

We report a new coherent imaging technique, termed ptychographic structured modulation (PSM), for quantitative super-resolution microscopy. In this technique, we place a thin diffuser (i.e., a scattering lens) in between the sample and the…

Image and Video Processing · Electrical Eng. & Systems 2019-07-26 Pengming Song , Shaowei Jiang , He Zhang , Zichao Bian , Chengfei Guo , Kazunori Hoshino , Guoan Zheng

Characterisation of rare microstructural features in scanning electron microscopy (SEM) requires imaging large areas at high resolution. This leads to prohibitively long acquisition times. We present an open-source Python framework that…

We propose a new approach, the calibrated nonparametric scan statistic (CNSS), for more accurate detection of anomalous patterns in large-scale, real-world graphs. Scan statistics identify connected subgraphs that are interesting or…

Methodology · Statistics 2022-06-28 Chunpai Wang , Daniel B. Neill , Feng Chen

Coarse-graining is a powerful tool for extending the reach of dynamic models of proteins and other biological macromolecules. Topological coarse-graining, in which biomolecules or sets thereof are represented via graph structures, is a…

Biomolecules · Quantitative Biology 2021-09-15 Vy Duong , Elizabeth Diessner , Gianmarc Grazioli , Rachel W. Martin , Carter T. Butts

To build a robust and practical content-based image retrieval (CBIR) system that is applicable to a clinical brain MRI database, we propose a new framework -- Disease-oriented image embedding with pseudo-scanner standardization (DI-PSS) --…

Computer Vision and Pattern Recognition · Computer Science 2023-03-24 Hayato Arai , Yuto Onga , Kumpei Ikuta , Yusuke Chayama , Hitoshi Iyatomi , Kenichi Oishi

The expanding research on manifold-based self-supervised learning (SSL) builds on the manifold hypothesis, which suggests that the inherent complexity of high-dimensional data can be unraveled through lower-dimensional manifold embeddings.…

Machine Learning · Computer Science 2024-05-24 Li Meng , Morten Goodwin , Anis Yazidi , Paal Engelstad

Large-scale volumetric medical images with annotation are rare, costly, and time prohibitive to acquire. Self-supervised learning (SSL) offers a promising pre-training and feature extraction solution for many downstream tasks, as it only…

Computer Vision and Pattern Recognition · Computer Science 2023-03-16 Ke Yu , Li Sun , Junxiang Chen , Max Reynolds , Tigmanshu Chaudhary , Kayhan Batmanghelich

Semi-supervised learning (SSL) is a promising machine learning paradigm to address the issue of label scarcity in medical imaging. SSL methods were originally developed in image classification. The state-of-the-art SSL methods in image…

Computer Vision and Pattern Recognition · Computer Science 2023-05-03 Mou-Cheng Xu , Yukun Zhou , Chen Jin , Marius De Groot , Neil P. Oxtoby , Daniel C. Alexander , Joseph Jacob

Fast and sensitive detector arrays enable image scanning microscopy (ISM), overcoming the trade-off between spatial resolution and signal-to-noise ratio (SNR) typical of confocal microscopy. However, current ISM approaches cannot provide…

Statistical Shape Modeling (SSM) effectively analyzes anatomical variations within populations but is limited by the need for manual localization and segmentation, which relies on scarce medical expertise. Recent advances in deep learning…

Computer Vision and Pattern Recognition · Computer Science 2024-07-10 Janmesh Ukey , Tushar Kataria , Shireen Y. Elhabian