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Domain-specific text embeddings are critical for clinical natural language processing, yet systematic comparisons across model architectures remain limited. This study evaluates ten transformer-based embedding models adapted for cardiology…

Computation and Language · Computer Science 2025-11-26 Richard J. Young , Alice M. Matthews

Transfer learning via fine-tuning pre-trained transformer models has gained significant success in delivering state-of-the-art results across various NLP tasks. In the absence of centralized data, Federated Learning (FL) can benefit from…

We study clinical Named Entity Recognition (NER) on the CADEC corpus and compare three families of approaches: (i) BERT-style encoders (BERT Base, BioClinicalBERT, RoBERTa-large), (ii) GPT-4o used with few-shot in-context learning (ICL)…

Computation and Language · Computer Science 2025-10-28 Andrei Baroian

Low-rank adaptation (LoRA) is one of the most popular task-specific parameter-efficient fine-tuning (PEFT) methods on pre-trained language models for its good performance and computational efficiency. LoRA injects a product of two trainable…

Machine Learning · Computer Science 2024-03-20 Youbang Sun , Zitao Li , Yaliang Li , Bolin Ding

Numerous real-world decisions rely on machine learning algorithms and require calibrated uncertainty estimates. However, modern methods often yield overconfident, uncalibrated predictions. The dominant approach to quantifying the…

Low-Rank Adaptation (LoRA) enables efficient fine-tuning of pre-trained language models through low-rank matrix approximation, achieving effectiveness in many scenarios. However, its representation capacity is constrained in complex tasks…

The scalability of deep learning models is fundamentally limited by computing resources, memory, and communication. Although methods like low-rank adaptation (LoRA) have reduced the cost of model finetuning, its application in model…

Machine Learning · Computer Science 2024-07-30 Minyoung Huh , Brian Cheung , Jeremy Bernstein , Phillip Isola , Pulkit Agrawal

Autoencoders have been recently used for encoding medical images. In this study, we design and validate a new framework for retrieving medical images by classifying Radon projections, compressed in the deepest layer of an autoencoder. As…

Computer Vision and Pattern Recognition · Computer Science 2017-10-04 Aditya Sriram , Shivam Kalra , H. R. Tizhoosh , Shahryar Rahnamayan

Multimodal self-supervised pretraining offers a promising route to cancer prognosis by integrating histopathology whole-slide images, gene expression, and pathology reports, yet most existing approaches require fully paired and complete…

Machine Learning · Computer Science 2026-04-08 Kai Yu , Shuang Zhou , Yiran Song , Zaifu Zhan , Jie Peng , Kaixiong Zhou , Tianlong Chen , Feng Xie , Meng Wang , Huazhu Fu , Mingquan Lin , Rui Zhang

The rapid advancements in vision-language models (VLMs), such as CLIP, have intensified the need to address distribution shifts between training and testing datasets. Although prior Test-Time Training (TTT) techniques for VLMs have…

Computer Vision and Pattern Recognition · Computer Science 2025-02-05 Yuto Kojima , Jiarui Xu , Xueyan Zou , Xiaolong Wang

In the rapidly evolving field of artificial intelligence, multimodal models, e.g., integrating vision and language into visual-language models (VLMs), have become pivotal for many applications, ranging from image captioning to multimodal…

Machine Learning · Computer Science 2024-04-24 Duy Phuong Nguyen , J. Pablo Munoz , Ali Jannesari

The rapid development of parameter-efficient fine-tuning methods has noticeably improved the efficiency of adapting large language models. Among these, LoRA has gained widespread popularity due to its strong balance of effectiveness and…

Machine Learning · Computer Science 2026-01-15 Yongfu Xue

In this research, we explored the improvement in terms of multi-class disease classification via pre-trained language models over Medical-Abstracts-TC-Corpus that spans five medical conditions. We excluded non-cancer conditions and examined…

Computation and Language · Computer Science 2024-11-20 Ahmed Akib Jawad Karim , Muhammad Zawad Mahmud , Samiha Islam , Aznur Azam

Fine-tuning adapts a pre-trained model to downstream tasks using a small amount of labeled data. Low-Rank Adaptation (LoRA) is an efficient fine-tuning method that reduces memory and computation costs while often achieving performance close…

Machine Learning · Computer Science 2026-05-20 Ali Zindari , Rotem Mulayoff , Sebastian U. Stich

We propose a simple approach for memory-efficient adaptation of pretrained language models. Our approach uses an iterative algorithm to decompose each pretrained matrix into a high-precision low-rank component and a memory-efficient…

Computation and Language · Computer Science 2024-08-28 Han Guo , Philip Greengard , Eric P. Xing , Yoon Kim

The pretrain+fine-tune paradigm is foundational for deploying large language models (LLMs) across various downstream applications. Within this framework, Low-Rank Adaptation (LoRA) stands out for its parameter-efficient fine-tuning (PEFT),…

Computation and Language · Computer Science 2024-10-10 Jingwei Xu , Junyu Lai , Yunpeng Huang

Fine-tuning is often necessary to enhance the adaptability of Large Language Models (LLM) to downstream tasks. Nonetheless, the process of updating billions of parameters demands significant computational resources and training time, which…

Computation and Language · Computer Science 2024-02-21 Tongxu Luo , Jiahe Lei , Fangyu Lei , Weihao Liu , Shizhu He , Jun Zhao , Kang Liu

Large pretrained language models have transformed natural language processing, and their adaptation to protein sequences -- viewed as strings of amino acid characters -- has advanced protein analysis. However, the distinct properties of…

Other Quantitative Biology · Quantitative Biology 2025-10-14 Sheikh Azizul Hakim , Kowshic Roy , M Saifur Rahman

Post-training has become essential for adapting large language models (LLMs) to complex downstream behaviors, including instruction following, preference alignment, and multi-step reasoning. Reinforcement learning with verifiable rewards…

Machine Learning · Computer Science 2026-05-20 Chengqian Zhang , Wei Zhu , Kyumin Lee

We introduce SetBERT, a fine-tuned BERT-based model designed to enhance query embeddings for set operations and Boolean logic queries, such as Intersection (AND), Difference (NOT), and Union (OR). SetBERT significantly improves retrieval…

Computation and Language · Computer Science 2024-06-27 Quan Mai , Susan Gauch , Douglas Adams