English

Enhancing Multi-Class Disease Classification: Neoplasms, Cardiovascular, Nervous System, and Digestive Disorders Using Advanced LLMs

Computation and Language 2024-11-20 v1 Artificial Intelligence

Abstract

In this research, we explored the improvement in terms of multi-class disease classification via pre-trained language models over Medical-Abstracts-TC-Corpus that spans five medical conditions. We excluded non-cancer conditions and examined four specific diseases. We assessed four LLMs, BioBERT, XLNet, and BERT, as well as a novel base model (Last-BERT). BioBERT, which was pre-trained on medical data, demonstrated superior performance in medical text classification (97% accuracy). Surprisingly, XLNet followed closely (96% accuracy), demonstrating its generalizability across domains even though it was not pre-trained on medical data. LastBERT, a custom model based on the lighter version of BERT, also proved competitive with 87.10% accuracy (just under BERT's 89.33%). Our findings confirm the importance of specialized models such as BioBERT and also support impressions around more general solutions like XLNet and well-tuned transformer architectures with fewer parameters (in this case, LastBERT) in medical domain tasks.

Keywords

Cite

@article{arxiv.2411.12712,
  title  = {Enhancing Multi-Class Disease Classification: Neoplasms, Cardiovascular, Nervous System, and Digestive Disorders Using Advanced LLMs},
  author = {Ahmed Akib Jawad Karim and Muhammad Zawad Mahmud and Samiha Islam and Aznur Azam},
  journal= {arXiv preprint arXiv:2411.12712},
  year   = {2024}
}

Comments

7 Pages, 4 tables and 11 figures. Under review in a IEEE conference

R2 v1 2026-06-28T20:05:21.030Z