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We use topological data analysis to study "functional networks" that we construct from time-series data from both experimental and synthetic sources. We use persistent homology with a weight rank clique filtration to gain insights into…

Quantitative Methods · Quantitative Biology 2017-05-24 Bernadette J. Stolz , Heather A. Harrington , Mason A. Porter

Topological data analysis can reveal higher-order structure beyond pairwise connections between vertices in complex networks. We present a new method based on discrete Morse theory to study topological properties of unweighted and…

Discrete Mathematics · Computer Science 2019-10-01 Harish Kannan , Emil Saucan , Indrava Roy , Areejit Samal

Modeling social systems as networks based on pairwise interactions between individuals offers valuable insights into the mechanisms underlying their dynamics. However, the majority of social interactions occur within groups of individuals,…

Physics and Society · Physics 2025-02-14 Liang Yuan , Jiao Wu , Kesheng Xu , Muhua Zheng

Several data-driven approaches based on information theory have been proposed for analyzing high-order interactions involving three or more components of a network system. Most of these methods are defined only in the time domain and rely…

Applications · Statistics 2025-03-18 Yuri Antonacci , Chiara Bara' , Laura Sparacino , Gorana Mijatovic , Ludovico Minati , Luca Faes

Many real-world phenomena are naturally modeled by graphs and networks. However, classical graph models are often limited to pairwise interactions and may not adequately capture the richer structures that arise in practice. Higher-order…

Social and Information Networks · Computer Science 2026-05-18 Takaaki Fujita , Florentin Smarandache

We propose a framework for constructing combinatorial complexes (CCs) from fMRI time series data that captures both pairwise and higher-order neural interactions through information-theoretic measures, bridging topological deep learning and…

Neurons and Cognition · Quantitative Biology 2026-01-06 Valentina Sánchez , Çiçek Güven , Koen Haak , Theodore Papamarkou , Gonzalo Nápoles , Marie Šafář Postma

Higher-order connectivity in complex systems described by simplexes of different orders provides a geometry for simplex-based dynamical variables and interactions. Simplicial complexes that constitute a functional geometry of the human…

Neurons and Cognition · Quantitative Biology 2020-06-19 Miroslav Andjelkovic , Bosiljka Tadic , Roderick Melnik

The human brain has a complex, intricate functional architecture. While many studies primarily emphasize pairwise interactions, delving into high-order associations is crucial for a comprehensive understanding of how functional brain…

Neurons and Cognition · Quantitative Biology 2023-10-30 Qiang Li , Vince D. Calhoun , Adithya Ram Ballem , Shujian Yu , Jesus Malo , Armin Iraji

A small-world topology characterizes many complex systems including the structural and functional organization of brain networks. The topology allows simultaneously for local and global efficiency in the interaction of the system…

Physics and Society · Physics 2015-05-30 Sinisa Pajevic , Dietmar Plenz

Recently there has been an increasing interest in studying dynamical processes on networks exhibiting higher-order structures, such as simplicial complexes, where the dynamics acts above and beyond dyadic interactions. Using simulations or…

Physics and Society · Physics 2023-09-25 István Z. Kiss , Iacopo Iacopini , Péter L. Simon , Nicos Georgiou

Recent evidence indicates that the abundance of recurring elementary interaction patterns in complex networks, often called subgraphs or motifs, carry significant information about their function and overall organization. Yet, the…

Disordered Systems and Neural Networks · Physics 2009-11-10 A. Vazquez , R. Dobrin , D. Sergi , J. -P. Eckmann , Z. N. Oltvai , A. -L. Barabasi

Thresholding--the pruning of nodes or edges based on their properties or weights--is an essential preprocessing tool for extracting interpretable structure from complex network data, yet existing methods face several key limitations.…

Social and Information Networks · Computer Science 2025-10-07 Adam Schroeder , Russell Funk , Jingyi Guan , Taylor Okonek , Lori Ziegelmeier

Many complex systems often contain interactions between more than two nodes, known as higher-order interactions, which can change the structure of these systems in significant ways. Researchers often assume that all interactions paint a…

Physics and Society · Physics 2024-02-16 Nicholas W. Landry , Ilya Amburg , Mirah Shi , Sinan G. Aksoy

Due to their ability to model meaningful higher order relations among a set of entities, higher order network models have emerged recently as a powerful alternative for graph-based network models which are only capable of modeling binary…

Machine Learning · Computer Science 2023-12-20 Karthikeyan Natesan Ramamurthy , Aldo Guzmán-Sáenz , Mustafa Hajij

Complex systems are characterized by many interacting units that give rise to emergent behavior. A particularly advantageous way to study these systems is through the analysis of the networks that encode the interactions among the system's…

Physics and Society · Physics 2019-03-21 Alberto Aleta , Yamir Moreno

In contrast to dyadic interactions, higher-order interactions may contain one another, with subgroups naturally embedded within larger groups. These containment patterns arise empirically in ecology, sociology, computer science and the…

Recent experiments have highlighted how collective dynamics in networks of brain regions affect behavior and cognitive function. In this paper we show that a simple, homogeneous system of densely connected oscillators representing the…

Pattern Formation and Solitons · Physics 2013-05-31 Rajeev Singh , Shakti N. Menon , Sitabhra Sinha

Functional brain network (FBN) modeling often relies on local pairwise interactions, whose limitation in capturing high-order dependencies is theoretically analyzed in this paper. Meanwhile, the computational burden and heuristic nature of…

Machine Learning · Computer Science 2025-10-13 Ling Zhan , Junjie Huang , Xiaoyao Yu , Wenyu Chen , Tao Jia

Many biological neuronal networks exhibit highly variable spiking activity. Balanced networks offer a parsimonious model of this variability. In balanced networks, strong excitatory synaptic inputs are canceled by strong inhibitory inputs…

Neurons and Cognition · Quantitative Biology 2016-05-04 Ryan Pyle , Robert Rosenbaum

Modular structure is ubiquitous among real-world networks from related proteins to social groups. Here we analyze the modular organization of brain networks at a large-scale (voxel level) extracted from functional magnetic resonance imaging…

Data Analysis, Statistics and Probability · Physics 2009-04-16 M. Valencia , M. A. Pastor , MA. Fernandez-Seara , J. Artieda , J. Martinerie , M. Chavez