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Functional networks provide a topological description of activity patterns in the brain, as they stem from the propagation of neural activity on the underlying anatomical or structural network of synaptic connections. This latter is well…

Disordered Systems and Neural Networks · Physics 2021-02-11 Ali Safari , Paolo Moretti , Ibai Diez , Jesus M. Cortes , Miguel Ángel Muñoz

Our goal in this paper is to leverage the potential of the topological signal processing (TSP) framework for analyzing brain networks. Representing brain data as signals over simplicial complexes allows us to capture higher-order…

Signal Processing · Electrical Eng. & Systems 2025-04-11 Breno C. Bispo , Stefania Sardellitti , Fernando A. N. Santos , Juliano B. Lima

Higher-order interactions provide a nuanced understanding of the relational structure of complex systems beyond traditional pairwise interactions. However, higher-order network analyses also incur more cumbersome interpretations and greater…

Physics and Society · Physics 2026-01-07 Alec Kirkley , Helcio Felippe , Federico Battiston

The study of irreducible higher-order interactions has become a core topic of study in complex systems. Two of the most well-developed frameworks, topological data analysis and multivariate information theory, aim to provide formal tools…

Information Theory · Computer Science 2025-04-15 Thomas F. Varley , Pedro A. M. Mediano , Alice Patania , Josh Bongard

Understanding the common topological characteristics of the human brain network across a population is central to understanding brain functions. The abstraction of human connectome as a graph has been pivotal in gaining insights on the…

Quantitative Methods · Quantitative Biology 2023-04-26 Soumya Das , D. Vijay Anand , Moo K. Chung

Topological representations are rapidly becoming a popular way to capture and encode higher-order interactions in complex systems. They have found applications in disciplines as different as cancer genomics, brain function, and…

Many topological data analysis (TDA) pipelines compute large collections of persistence diagrams, yet vectorizations and kernel methods discard the rank-induced implication relations among persistence intervals that are essential for…

Computational Geometry · Computer Science 2026-05-12 Charles Fanning , Mehmet Aktas

The irreducible complexity of natural phenomena has led Graph Neural Networks to be employed as a standard model to perform representation learning tasks on graph-structured data. While their capacity to capture local and global patterns is…

Machine Learning · Computer Science 2024-02-13 Lorenzo Giusti

The relation between large-scale brain structure and function is an outstanding open problem in neuroscience. We approach this problem by studying the dynamical regime under which realistic spatio-temporal patterns of brain activity emerge…

Neurons and Cognition · Quantitative Biology 2014-05-27 Ariel Haimovici , Enzo Tagliazucchi , Pablo Balenzuela , Dante R. Chialvo

Network science has evolved into an indispensable platform for studying complex systems. But recent research has identified limits of classical networks, where links connect pairs of nodes, to comprehensively describe group interactions.…

Physics and Society · Physics 2022-03-24 Soumen Majhi , Matjaz Perc , Dibakar Ghosh

Complex systems are often driven by higher-order interactions among multiple units, naturally represented as hypergraphs. Understanding dependency structures within these hypergraphs is crucial for understanding and predicting the behavior…

Social and Information Networks · Computer Science 2025-05-29 John Hood , Caterina De Bacco , Aaron Schein

Functional brain network has been widely studied to understand the relationship between brain organization and behavior. In this paper, we aim to explore the functional connectivity of brain network under a \emph{multi-step} cognitive task…

Neurons and Cognition · Quantitative Biology 2017-12-06 Shi-Min Cai , Wei Chen , Dong-Bai Liu , Ming Tang , Xun Chen

Higher-order networks have emerged as a powerful framework to model complex systems and their collective behavior. Going beyond pairwise interactions, they encode structured relations among arbitrary numbers of units through representations…

Adaptation and Self-Organizing Systems · Physics 2023-03-24 Yuanzhao Zhang , Maxime Lucas , Federico Battiston

Discovering reliable and informative relationships among brain regions from functional magnetic resonance imaging (fMRI) signals is essential in phenotypic predictions. Most of the current methods fail to accurately characterize those…

Neurons and Cognition · Quantitative Biology 2024-06-11 Weikang Qiu , Huangrui Chu , Selena Wang , Haolan Zuo , Xiaoxiao Li , Yize Zhao , Rex Ying

Higher-order networks are gaining significant scientific attention due to their ability to encode the many-body interactions present in complex systems. However, higher-order networks have the limitation that they only capture many-body…

Adaptation and Self-Organizing Systems · Physics 2023-12-20 Sanjukta Krishnagopal , Ginestra Bianconi

Graph neural networks have become the default choice by practitioners for graph learning tasks such as graph classification and node classification. Nevertheless, popular graph neural network models still struggle to capture higher-order…

Machine Learning · Computer Science 2024-11-27 Davide Buffelli , Farzin Soleymani , Bastian Rieck

Networks can describe the structure of a wide variety of complex systems by specifying which pairs of entities in the system are connected. While such pairwise representations are flexible, they are not necessarily appropriate when the…

Social and Information Networks · Computer Science 2022-01-17 Jean-Gabriel Young , Giovanni Petri , Tiago P. Peixoto

Graphs serve as powerful tools for modeling pairwise interactions in diverse fields such as biology, material science, and social networks. However, they inherently overlook interactions involving more than two entities. Simplicial…

Algebraic Topology · Mathematics 2024-12-05 Xiang Liu , Ran Liu , Jingyan Li , Rongling Wu , Jie Wu

Functional brain connectivity changes dynamically over time, making its representation challenging for learning on non-Euclidean data. We present a framework that encodes dynamic functional connectivity as an image representation of…

Neurons and Cognition · Quantitative Biology 2025-11-14 Peilin He , Tananun Songdechakraiwut

The rapid progress of Artificial Intelligence research came with the development of increasingly complex deep learning models, leading to growing challenges in terms of computational complexity, energy efficiency and interpretability. In…

Machine Learning · Computer Science 2023-06-28 Yuanrong Wang , Antonio Briola , Tomaso Aste