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Related papers: Zero-Shot Denoising for Fluorescence Lifetime Imag…

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Most existing Image Restoration (IR) models are task-specific, which can not be generalized to different degradation operators. In this work, we propose the Denoising Diffusion Null-Space Model (DDNM), a novel zero-shot framework for…

Computer Vision and Pattern Recognition · Computer Science 2022-12-08 Yinhuai Wang , Jiwen Yu , Jian Zhang

Light-field microscopy (LFM) enables rapid volumetric imaging through single-frame acquisition and fast 3D reconstruction algorithms. The high speed and low phototoxicity of LFM make it highly suitable for real-time 3D fluorescence imaging,…

Optics · Physics 2025-02-24 Bohan Qu , Zhouyu Jin , You Zhou , Bo Xiong , Xun Cao

Structured illumination microscopy (SIM) is an important super-resolution based microscopy technique that breaks the diffraction limit and enhances optical microscopy systems. With the development of biology and medical engineering, there…

Image and Video Processing · Electrical Eng. & Systems 2021-11-18 Xi Cheng , Jun Li , Qiang Dai , Zhenyong Fu , Jian Yang

Noise is a major issue while transferring images through all kinds of electronic communication. One of the most common noise in electronic communication is an impulse noise which is caused by unstable voltage. In this paper, the comparison…

Computer Vision and Pattern Recognition · Computer Science 2014-10-09 Suman Shrestha

Accurate intraoperative assessment of glioma infiltration is essential for maximizing tumor resection while preserving functional brain tissue. Fluorescence lifetime imaging (FLIm) offers real-time, label-free biochemical contrast, but its…

Computer Vision and Pattern Recognition · Computer Science 2026-04-30 Silvia Noble Anbunesan , Mohamed Abul Hassan , Jinyi Qi , Lisanne Kraft , Han Sung Lee , Orin Bloch , Laura Marcu

High-throughput biological imaging is often constrained by a trade-off between acquisition speed and image quality. Fast imaging modalities, such as wide-field fluorescence microscopy, enable large-scale data acquisition but suffer from…

Image and Video Processing · Electrical Eng. & Systems 2026-04-20 Dominik Panek , Carina Rząca , Maksymilian Szczypior , Joanna Sorysz , Krzysztof Misztal , Zbigniew Baster , Zenon Rajfur

Despite their widespread use in cell biology, fluorescence lifetime imaging microscopy (FLIM) data-sets are challenging to analyse, because each spatial position can contain a superposition of multiple fluorescent components. Here, we…

Biological Physics · Physics 2022-08-29 Francesco Masia , Walter Dewitte , Paola Borri , Wolfgang Langbein

Large amount of image denoising literature focuses on single channel images and often experimentally validates the proposed methods on tens of images at most. In this paper, we investigate the interaction between denoising and…

Computer Vision and Pattern Recognition · Computer Science 2017-04-06 Jiqing Wu , Radu Timofte , Zhiwu Huang , Luc Van Gool

Image denoising is a typical ill-posed problem due to complex degradation. Leading methods based on normalizing flows have tried to solve this problem with an invertible transformation instead of a deterministic mapping. However, the…

Computer Vision and Pattern Recognition · Computer Science 2023-02-01 Wenchao Du , Hu Chen , Yi Zhang , H. Yang

With the advent of advances in self-supervised learning, paired clean-noisy data are no longer required in deep learning-based image denoising. However, existing blind denoising methods still require the assumption with regard to noise…

Computer Vision and Pattern Recognition · Computer Science 2021-09-10 Kanggeun Lee , Won-Ki Jeong

In computer-aided diagnosis (CAD) focused on microscopy, denoising improves the quality of image analysis. In general, the accuracy of this process may depend both on the experience of the microscopist and on the equipment sensitivity and…

Image and Video Processing · Electrical Eng. & Systems 2021-05-04 Fabio Hernán Gil Zuluaga , Francesco Bardozzo , Jorge Iván Ríos Patiño , Roberto Tagliaferri

In this work, we present denoiSplit, a method to tackle a new analysis task, i.e. the challenge of joint semantic image splitting and unsupervised denoising. This dual approach has important applications in fluorescence microscopy, where…

Image and Video Processing · Electrical Eng. & Systems 2024-08-13 Ashesh Ashesh , Florian Jug

Noise is a significant challenge in imaging. Conventional intensity-based techniques mitigate noise through various filtering methods, but they often require prior knowledge of noise characteristics and struggle, especially under low-light…

Optics · Physics 2026-05-12 Pranay Mohta , Keval Moliya , Aniket Nag , Shaurya Aarav , Anand Kumar Jha

Photoluminesce (PL) spectroscopy offers excellent methods for mapping the PL decay on the nanosecond time scale. However, capturing maps of emission dynamics on the microsecond time scale can be highly time-consuming. We present a new…

Optics · Physics 2021-02-24 Jiri Junek , Karel Zidek

In recent years, it has become popular to tackle image restoration tasks with a single pretrained diffusion model (DM) and data-fidelity guidance, instead of training a dedicated deep neural network per task. However, such "zero-shot"…

Computer Vision and Pattern Recognition · Computer Science 2025-04-07 Tomer Garber , Tom Tirer

Noise is an inherent issue of low-light image capture, one which is exacerbated on mobile devices due to their narrow apertures and small sensors. One strategy for mitigating noise in a low-light situation is to increase the shutter time of…

Computer Vision and Pattern Recognition · Computer Science 2017-12-18 Clément Godard , Kevin Matzen , Matt Uyttendaele

Wide-field imaging Mueller polarimetry is a revolutionary, label-free, and non-invasive modality for computer-aided intervention: in neurosurgery it aims to provide visual feedback of white matter fibre bundle orientation from derived…

Patient scans from MRI often suffer from noise, which hampers the diagnostic capability of such images. As a method to mitigate such artifact, denoising is largely studied both within the medical imaging community and beyond the community…

Image and Video Processing · Electrical Eng. & Systems 2022-03-25 Hyungjin Chung , Eun Sun Lee , Jong Chul Ye

We propose to learn a fully-convolutional network model that consists of a Chain of Identity Mapping Modules (CIMM) for image denoising. The CIMM structure possesses two distinctive features that are important for the noise removal task.…

Computer Vision and Pattern Recognition · Computer Science 2019-07-22 Saeed Anwar , Cong Phouc Huynh , Fatih Porikli

Fluorescence guided surgery (FGS) is a promising surgical technique that gives surgeons a unique view of tissue that is used to guide their practice by delineating tissue types and diseased areas. As new fluorescent contrast agents are…

Computer Vision and Pattern Recognition · Computer Science 2024-11-18 Trevor Seets , Andreas Velten