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Atomic resolution STEM images often suffer from noise due to low electron doses and instrument imperfections, hence it is challenging to obtain critical structural details required for material analysis. To address the problem, we propose a…

Materials Science · Physics 2024-12-18 Z. Awan , J. Shabeer , U. Saleem , S. Mehmood , T. Qadeer

Enhancing the visibility in extreme low-light environments is a challenging task. Under nearly lightless condition, existing image denoising methods could easily break down due to significantly low SNR. In this paper, we systematically…

Image and Video Processing · Electrical Eng. & Systems 2021-08-05 Kaixuan Wei , Ying Fu , Yinqiang Zheng , Jiaolong Yang

Due to image blurring image deconvolution is often used for studying biological structures in fluorescence microscopy. Fluorescence microscopy image volumes inherently suffer from intensity inhomogeneity, blur, and are corrupted by various…

Computer Vision and Pattern Recognition · Computer Science 2019-07-15 Soonam Lee , Shuo Han , Paul Salama , Kenneth W. Dunn , Edward J. Delp

We introduce Transductive Infomation Maximization (TIM) for few-shot learning. Our method maximizes the mutual information between the query features and their label predictions for a given few-shot task, in conjunction with a supervision…

Machine Learning · Computer Science 2020-10-26 Malik Boudiaf , Ziko Imtiaz Masud , Jérôme Rony , José Dolz , Pablo Piantanida , Ismail Ben Ayed

In this paper, we introduce a novel unsupervised network to denoise microscopy videos featured by image sequences captured by a fixed location microscopy camera. Specifically, we propose a DeepTemporal Interpolation method, leveraging a…

Image and Video Processing · Electrical Eng. & Systems 2024-04-19 Mary Aiyetigbo , Alexander Korte , Ethan Anderson , Reda Chalhoub , Peter Kalivas , Feng Luo , Nianyi Li

This paper reported a bespoke adder-based deep learning network for time-domain fluorescence lifetime imaging (FLIM). By leveraging the l1-norm extraction method, we propose a 1-D Fluorescence Lifetime AdderNet (FLAN) without…

Signal Processing · Electrical Eng. & Systems 2022-09-13 Zhenya Zang , Dong Xiao , Quan Wang , Ziao Jiao , Chen Yu , David Day-Uei Li

Fully supervised deep-learning based denoisers are currently the most performing image denoising solutions. However, they require clean reference images. When the target noise is complex, e.g. composed of an unknown mixture of primary…

Image and Video Processing · Electrical Eng. & Systems 2020-08-03 Florian Lemarchand , Erwan Nogues , Maxime Pelcat

Diffusion magnetic resonance imaging (dMRI) plays a vital role in both clinical diagnostics and neuroscience research. However, its inherently low signal-to-noise ratio (SNR), especially under high diffusion weighting, significantly…

Quantitative Methods · Quantitative Biology 2026-02-27 Jine Xie , Zhicheng Zhang , Yunwei Chen , Yanqiu Feng , Xinyuan Zhang

We present a physics-informed deep learning framework to address common limitations in Confocal Laser Scanning Microscopy (CLSM), such as diffraction limited resolution, noise, and undersampling due to low laser power conditions. The…

Materials Science · Physics 2025-01-27 Zaheer Ahmad , Junaid Shabeer , Usman Saleem , Tahir Qadeer , Abdul Sami , Zahira El Khalidi , Saad Mehmood

Fluorescence microscopy allows for a detailed inspection of cells, cellular networks, and anatomical landmarks by staining with a variety of carefully-selected markers visualized as color channels. Quantitative characterization of…

Computer Vision and Pattern Recognition · Computer Science 2021-08-26 Alvaro Gomariz , Tiziano Portenier , Patrick M. Helbling , Stephan Isringhausen , Ute Suessbier , César Nombela-Arrieta , Orcun Goksel

Biomedical images are noisy. The imaging equipment itself has physical limitations, and the consequent experimental trade-offs between signal-to-noise ratio, acquisition speed, and imaging depth exacerbate the problem. Denoising is,…

Image and Video Processing · Electrical Eng. & Systems 2020-11-11 Mikhail Papkov , Kenny Roberts , Lee Ann Madissoon , Omer Bayraktar , Dmytro Fishman , Kaupo Palo , Leopold Parts

The high-content image-based assay is commonly leveraged for identifying the phenotypic impact of genetic perturbations in biology field. However, a persistent issue remains unsolved during experiments: the interferential technical noise…

Image and Video Processing · Electrical Eng. & Systems 2022-12-09 Sen Yang , Tao Shen , Yuqi Fang , Xiyue Wang , Jun Zhang , Wei Yang , Junzhou Huang , Xiao Han

Low fluence illumination sources can facilitate clinical transition of photoacoustic imaging because they are rugged, portable, affordable, and safe. However, these sources also decrease image quality due to their low fluence. Here, we…

Image and Video Processing · Electrical Eng. & Systems 2020-04-21 Ali Hariri , Kamran Alipour , Yash Mantri , Jurgen P. Schulze , Jesse V. Jokerst

Compressive Macroscopic Fluorescence Lifetime Imaging (MFLI) is a novel technical implementation that enables monitoring multiple molecular interactions in macroscopic scale. Especially, we reported recently on the development of a…

Medical Physics · Physics 2018-02-23 Ruoyang Yao , Marien Ochoa , Xavier Intes , Pingkun Yan

Background noise in many fields such as medical imaging poses significant challenges for accurate diagnosis, prompting the development of denoising algorithms. Traditional methodologies, however, often struggle to address the complexities…

Image and Video Processing · Electrical Eng. & Systems 2025-02-03 Amirreza Hashemi , Sayantan Dutta , Bertrand Georgeot , Denis Kouame , Hamid Sabet

Noisy images are a challenge to image compression algorithms due to the inherent difficulty of compressing noise. As noise cannot easily be discerned from image details, such as high-frequency signals, its presence leads to extra bits…

Image and Video Processing · Electrical Eng. & Systems 2024-02-09 Yuxin Xie , Li Yu , Farhad Pakdaman , Moncef Gabbouj

Image denoising stands as a critical challenge in image processing and computer vision, aiming to restore the original image from noise-affected versions caused by various intrinsic and extrinsic factors. This process is essential for…

Image and Video Processing · Electrical Eng. & Systems 2024-03-19 Peter Luvton , Alfredo Castillejos , Jim Zhao , Christina Chajo

Fluorescent imaging plays a critical role in a myriad of scientific endeavors, particularly in the biological sciences. Three-dimensional imaging of fluorescent intensity often requires serial data acquisition, that is voxel-by-voxel…

Optics · Physics 2015-10-27 Jeffrey J. Field , David G. Winters , Randy A. Bartels

We propose an efficient neural network for RAW image denoising. Although neural network-based denoising has been extensively studied for image restoration, little attention has been given to efficient denoising for compute limited and power…

Image and Video Processing · Electrical Eng. & Systems 2021-03-19 Lucas D. Young , Fitsum A. Reda , Rakesh Ranjan , Jon Morton , Jun Hu , Yazhu Ling , Xiaoyu Xiang , David Liu , Vikas Chandra

Denoising, the process of reducing random fluctuations in a signal to emphasize essential patterns, has been a fundamental problem of interest since the dawn of modern scientific inquiry. Recent denoising techniques, particularly in…

Machine Learning · Computer Science 2024-12-04 Peyman Milanfar , Mauricio Delbracio
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