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Asymmetric binary classification problems, in which the type I and II errors have unequal severity, are ubiquitous in real-world applications. To handle such asymmetry, researchers have developed the cost-sensitive and Neyman-Pearson…

Machine Learning · Statistics 2021-01-01 Wei Vivian Li , Xin Tong , Jingyi Jessica Li

The power of multiple testing procedures can be increased by using weighted p-values (Genovese, Roeder and Wasserman 2005). We derive the optimal weights and we show that the power is remarkably robust to misspecification of these weights.…

Statistics Theory · Mathematics 2007-06-13 Larry Wasserman , Kathryn Roeder

Simultaneously testing $K$ hypotheses while controlling the family-wise error rate is a fundamental problem in statistics. Existing procedures (Bonferroni, Holm, Hochberg, Hommel) provide valid control but sacrifice power, increasingly so…

Methodology · Statistics 2026-04-14 Prasanjit Dubey , Xiaoming Huo

We study a statistical framework for replicability based on a recently proposed quantitative measure of replication success, the sceptical $p$-value. A recalibration is proposed to obtain exact overall Type-I error control if the effect is…

Methodology · Statistics 2023-11-10 Charlotte Micheloud , Fadoua Balabdaoui , Leonhard Held

A central problem in Binary Hypothesis Testing (BHT) is to determine the optimal tradeoff between the Type I error (referred to as false alarm) and Type II (referred to as miss) error. In this context, the exponential rate of convergence of…

Information Theory · Computer Science 2021-11-29 Sebastian Espinosa , Jorge F. Silva , Pablo Piantanida

We connect the power of Confidence Intervals in different Frequentist methods to their reliability. We show that in the case of a bounded parameter a biased method which near the boundary has large power in testing the parameter against…

High Energy Physics - Experiment · Physics 2007-05-23 C. Giunti , M. Laveder

Hybrid controlled trials (HCTs), which augment randomized controlled trials (RCTs) with external controls (ECs), are increasingly receiving attention as a way to address limited power, slow accrual, and ethical concerns in clinical…

Methodology · Statistics 2025-05-02 Jiajun Liu , Ke Zhu , Shu Yang , Xiaofei Wang

We review approaches to statistical inference based on randomization. Permutation tests are treated as an important special case. Under a certain group invariance property, referred to as the ``randomization hypothesis,'' randomization…

Econometrics · Economics 2025-02-05 David M. Ritzwoller , Joseph P. Romano , Azeem M. Shaikh

Businesses frequently run online controlled experiments (i.e., A/B tests) to learn about the effect of an intervention on multiple business metrics. To account for multiple hypothesis testing, multiple metrics are commonly aggregated into a…

Methodology · Statistics 2026-01-22 Luke Hagar , Nathaniel T. Stevens

An important issue for many economic experiments is how the experimenter can ensure sufficient power for rejecting one or more hypotheses. Here, we apply methods developed mainly within the area of clinical trials for testing multiple…

Methodology · Statistics 2021-08-06 Sebastian Jobjörnsson , Henning Schaak , Oliver Mußhoff , Tim Friede

Replication studies for scientific research are an important part of ensuring the reliability and integrity of experimental findings. In the context of clinical trials, the concept of replication has been formalised by the 'two-trials'…

Methodology · Statistics 2025-10-27 David S. Robertson , Thomas Jaki

Selective classification enhances the reliability of predictive models by allowing them to abstain from making uncertain predictions. In this work, we revisit the design of optimal selection functions through the lens of the Neyman--Pearson…

Machine Learning · Computer Science 2026-03-04 Alvin Heng , Harold Soh

We develop new methods for constructing confidence sets and intervals in linear instrumental variables (IV) models based on tests that remain valid under weak identification and under heteroskedastic, autocorrelated, or clustered errors. In…

Econometrics · Economics 2026-04-07 Gustavo Schlemper , Marcelo J. Moreira

We propose a general methodology for testing whether a given polynomial with integer coefficients is identically zero. The methodology evaluates the polynomial at efficiently computable approximations of suitable irrational points. In…

Data Structures and Algorithms · Computer Science 2007-05-23 Zhi-Zhong Chen , Ming-Yang Kao

We consider finite-sample inference for a single regression coefficient in the fixed-design linear model $Y = Z\beta + bX + \varepsilon$, where $\varepsilon\in\mathbb{R}^n$ may exhibit complex dependence or heterogeneity. We develop a group…

Methodology · Statistics 2026-04-20 Zonghan Li , Hongyi Zhou , Zhiheng Zhang

We propose a method for multiple hypothesis testing with familywise error rate (FWER) control, called the i-FWER test. Most testing methods are predefined algorithms that do not allow modifications after observing the data. However, in…

Methodology · Statistics 2021-04-20 Boyan Duan , Aaditya Ramdas , Larry Wasserman

We construct exact confidence intervals for the average treatment effect in randomized experiments with binary outcomes using sequences of randomization tests. Our approach does not rely on large-sample approximations and is valid for all…

Methodology · Statistics 2026-02-25 Peng Zhang

Kernel two-sample tests have been widely used, and the development of efficient methods for high-dimensional, large-scale data is receiving increasing attention in the big data era. However, existing methods, such as the maximum mean…

Methodology · Statistics 2025-10-03 Hoseung Song , Hao Chen

Testing differences in mean vectors is a fundamental task in the analysis of high-dimensional compositional data. Existing methods may suffer from low power if the underlying signal pattern is in a situation that does not favor the deployed…

Methodology · Statistics 2025-03-11 Danning Li , Lingzhou Xue , Haoyi Yang , Xiufan Yu

The problem of binary hypothesis testing between two probability measures is considered. New sharp bounds are derived for the best achievable error probability of such tests based on independent and identically distributed observations.…

Information Theory · Computer Science 2024-05-30 Valentinian Lungu , Ioannis Kontoyiannis