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Recent advances in the field of attosecond science hold the promise of tracking electronic processes at the shortest space and time scales. Imaging methods that combine attosecond temporal with nanometer spatial resolution are currently out…

This review article provides a contemporary overview of phase retrieval in optical imaging, linking the relevant optical physics to the information processing methods and algorithms. Its purpose is to describe the current state of the art…

Information Theory · Computer Science 2014-03-03 Yoav Shechtman , Yonina C. Eldar , Oren Cohen , Henry N. Chapman , Jianwei Miao , Mordechai Segev

Complementary to conventional and phase X-ray radiography, dark-field imaging has become central in visualizing diffusive scattering signal due to the spatially-unresolved texture within an object. To date most diffusive-dark-field…

Medical Physics · Physics 2023-03-21 Mario A. Beltran , David M. Paganin , Michelle K. Croughan , Kaye S. Morgan

Coherent diffraction imaging (CDI) allows the retrieval of the structure of an isolated object, such as a macromolecule, from its diffraction pattern. CDI requires the fulfilment of two conditions: the imaging radiation must be coherent and…

Optics · Physics 2018-11-16 Tatiana Latychevskaia , Hans-Werner Fink

Coherent diffractive imaging (CDI) has been widely applied in the physical and biological sciences using synchrotron radiation, XFELs, high harmonic generation, electrons and optical lasers. One of CDI's important applications is to probe…

Instrumentation and Detectors · Physics 2018-07-04 Yuan Hung Lo , Lingrong Zhao , Marcus Gallagher-Jones , Arjun Rana , Jared Lodico , Weikun Xiao , B. C. Regan , Jianwei Miao

The structural complexity and instability of many interference phase microscopy methods are the major obstacles toward high-precision phase measurement. In this vein, improving more efficient configurations as well as proposing new methods…

Optics · Physics 2020-01-08 Samira Ebrahimi , Masoomeh Dashtdar

We demonstrate that in situ coherent diffractive imaging (CDI), which harnesses the coherent interference between a strong and a weak beam illuminating a static and dynamic structure, can be a very dose-efficient imaging method. At low…

The scientific community has witnessed tremendous expansion of research on layered (i.e. two-dimensional, 2D) materials, with increasing recent focus on applications to photonics. Layered materials are particularly exciting for manipulating…

Materials Science · Physics 2020-11-17 Akshay Singh , Seong Soon Jo , Yifei Li , Changming Wu , Mo Li , R. Jaramillo

We developed a microscopy technique that can measure the local refractive index without sampling the optical phase delay of the electromagnetic radiation. To do this, we designed and experimentally demonstrated a setup with two co-localized…

Optics · Physics 2019-03-27 Antonio Fiore , Carlo Bevilacqua , Giuliano Scarcelli

Cells alter the path of light, a fact that leads to well-known aberrations in single cell or tissue imaging. Optical diffraction tomography (ODT) measures the biophysical property that causes these aberrations, the refractive index (RI).…

Quantitative Methods · Quantitative Biology 2017-08-14 Mirjam Schürmann , Gheorghe Cojoc , Salvatore Girardo , Elke Ulbricht , Jochen Guck , Paul Müller

We present an algorithm for coherent diffractive imaging with phaseless measurements. It treats the forward model as a combination of coherent and incoherent waves. The algorithm reconstructs absorption and phase contrast that quantifies…

Computational Physics · Physics 2022-08-25 Miguel Moscoso , Alexei Novikov , George Papanicolaou , Chrysoula Tsogka

Diffusion-weighted imaging (DWI) is a powerful non-invasive tool which is widely used in clinical routine. Mostly, apparent diffusion coefficient maps are acquired, which cannot be directly related to cellular structure. More recently it…

Wavefront sensing involves estimating the phase and intensity of light, enabling a wide range of imaging applications, from adaptive optics and astronomy to biomedical imaging. Since conventional image sensors can only measure the spatial…

Image and Video Processing · Electrical Eng. & Systems 2026-04-07 Nebiyou Yismaw , Vishwanath Saragadam , Aswin C. Sankaranarayanan , M. Salman Asif

In both light optics and electron optics, the amplitude of a wave scattered by an object is an observable that is usually recorded in the form of an intensity distribution in a real space image or a diffraction image. In contrast, retrieval…

A novel optical technique for measuring the complex refractive index (CRI) of photoactive proteins over the wide range of visible wavelengths is presented. Employing quantitative phase microscopy equipped with a wavelength swept source,…

Chemical Physics · Physics 2015-07-03 KyeoReh Lee , Youngmin Kim , JaeHwang Jung , Hyotcherl Ihee , YongKeun Park

The health of cells found in the inner retinal layers of the human eye is crucial to understand the onset of diseases of the retina such as macular degeneration and retinopathy. A challenge is to periodically image these cells in human eyes…

Formation of a bright-field microscopic image of a transparent phase object is described in terms of elementary geometrical optics. Our approach is based on the premise that image replicates the intensity distribution (real or virtual) at…

Optics · Physics 2018-02-14 A. K. Khitrin , M. A. Model

The ill-posed problem of phase retrieval in optics, using one or more intensity measurements, has a multitude of applications using electromagnetic or matter waves. Many phase retrieval algorithms are computed on pixel arrays using discrete…

Image and Video Processing · Electrical Eng. & Systems 2022-09-21 J. A. Pollock , K. S. Morgan , L. C. P. Croton , M. K. Croughan , G. Ruben , N. Yagi , H. Sekiguchi , M. J. Kitchen

Optical microscopy is without a doubt an essential component of life science research, but many objects of interest in biology are transparent. Chemical or immunological dyes, which can often be toxic, fluorescent transgenes, which require…

Optics · Physics 2012-09-11 Quintin Tyrell Davis

We introduce a novel, training-free method for sampling differentiable representations (diffreps) using pretrained diffusion models. Rather than merely mode-seeking, our method achieves sampling by "pulling back" the dynamics of the…

Computer Vision and Pattern Recognition · Computer Science 2024-12-11 Yash Savani , Marc Finzi , J. Zico Kolter
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