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The aim of the present paper is to provide necessary and sufficient conditions to maintain a stochastic coupled system, with porous media components and gradient-type noise in a prescribed set of constraints by using internal controls. This…

Analysis of PDEs · Mathematics 2022-02-08 Ioana Ciotir , Dan Goreac , Ionut Munteanu

The dynamical evolution of a tumor growth model, under immune surveillance and subject to asymmetric non-Gaussian $\alpha$-stableL\'evy noise, is explored. The lifetime of a tumor staying in the range between the tumor-free state and the…

Dynamical Systems · Mathematics 2012-11-12 Mengli Hao , Jinqiao Duan , Renming Song , Wei Xu

This paper focuses on the numerical stability of stochastic McKean-Vlasov equations (SMVEs) via the stochastic particle method. Firstly, the long-time propagation of chaos in the mean-square sense is obtained, and the almost sure…

Numerical Analysis · Mathematics 2025-08-04 Zhuoqi Liu , Shuaibin Gao , Chenggui Yuan , Qian Guo

This paper presents the open-source stochastic model predictive control framework GRAMPC-S for nonlinear uncertain systems with chance constraints. It provides several uncertainty propagation methods to predict stochastic moments of the…

Systems and Control · Electrical Eng. & Systems 2025-07-25 Daniel Landgraf , Andreas Völz , Knut Graichen

Stochastic Galerkin formulations of the two-dimensional shallow water systems parameterized with random variables may lose hyperbolicity, and hence change the nature of the original model. In this work, we present a hyperbolicity-preserving…

Numerical Analysis · Mathematics 2022-01-26 Dihan Dai , Yekaterina Epshteyn , Akil Narayan

The numerical approximation of high-dimensional evolution equations poses significant computational challenges, particularly in kinetic theory and radiative transfer. In this work, we introduce the Galerkin Alternating Projection (GAP)…

Numerical Analysis · Mathematics 2025-05-27 Gianluca Ceruti , Nicolas Crouseilles , Lukas Einkemmer

In this paper, we study the tumor growth equation along with various models for the nutrient component, including the \emph{in vitro} model and the \emph{in vivo} model. At the cell density level, the spatial availability of the tumor…

Analysis of PDEs · Mathematics 2018-02-05 Jian-Guo Liu , Min Tang , Li Wang , Zhennan Zhou

This paper deals with a general system of equations and conditions arising from a mathematical model of prostate cancer growth with chemotherapy and antiangiogenic therapy that has been recently introduced and analyzed (see [P. Colli et…

Analysis of PDEs · Mathematics 2021-04-02 Pierluigi Colli , Gianni Gilardi , Jürgen Sprekels

We present a computational framework for solving the equations of inviscid gas dynamics using structured grids with embedded geometries. The novelty of the proposed approach is the use of high-order discontinuous Galerkin (dG) schemes and a…

Numerical Analysis · Mathematics 2022-01-05 Vincenzo Gulizzi , Ann S. Almgren , John B. Bell

This paper presents stochastic virtual element methods for propagating uncertainty in linear elastic stochastic problems. We first derive stochastic virtual element equations for 2D and 3D linear elastic problems that may involve…

Numerical Analysis · Mathematics 2023-11-01 Zhibao Zheng , Udo Nackenhorst

We consider the inverse problem of identifying parameters in a variant of the diffuse interface model for tumour growth model proposed by Garcke, Lam, Sitka and Styles (Math. Models Methods Appl. Sci. 2016). The model contains three…

Optimization and Control · Mathematics 2017-07-24 Christian Kahle , Kei Fong Lam

Cancer is a very complex phenomenon that involves many different scales and situations. In this paper we consider a free boundary problem describing the evolution of a tumor colony and we derive a new asymptotic model for tumor growth. We…

Analysis of PDEs · Mathematics 2025-04-15 Rafael Granero-Belinchón , Martina Magliocca

In this work, we present a coupled 3D-1D model of solid tumor growth within a dynamically changing vascular network to facilitate realistic simulations of angiogenesis. Additionally, the model includes erosion of the extracellular matrix,…

Tissues and Organs · Quantitative Biology 2021-06-23 Marvin Fritz , Prashant K. Jha , Tobias Köppl , J. Tinsley Oden , Andreas Wagner , Barbara Wohlmuth

In this paper, we develop the mathematical framework for filtering problems arising from biophysical applications where data is collected from confocal laser scanning microscopy recordings of the space-time evolution of intracellular wave…

Statistics Theory · Mathematics 2025-06-10 Jan Szalankiewicz , Cristina Martinez-Torres , Wilhelm Stannat

In this paper a macroscopic model of tumor cord growth is developed, relying on the mathematical theory of deformable porous media. Tumor is modeled as a saturated mixture of proliferating cells, extracellular fluid and extracellular…

Mathematical Physics · Physics 2010-11-09 Andrea Tosin

We propose a new pressure-based structure-preserving (SP) and quasi asymptotic preserving (AP) staggered semi-implicit finite volume scheme for the unified first order hyperbolic formulation of continuum mechanics. The unified model is…

Fluid Dynamics · Physics 2020-11-05 Walter Boscheri , Michael Dumbser , Matteo Ioriatti , Ilya Peshkov , Evgeniy Romenski

In this work we explore the temporal dynamics of spatial heterogeneity during the process of tumorigenesis from healthy tissue. We utilize a spatial stochastic process model of mutation accumulation and clonal expansion in a structured…

Populations and Evolution · Quantitative Biology 2015-11-03 K. Storey , M. D. Ryser , K. Leder , J. Foo

Determining the physical characteristics of a star is an inverse problem consisting in estimating the parameters of models for the stellar structure and evolution, knowing certain observable quantities. We use a Bayesian approach to solve…

Solar and Stellar Astrophysics · Physics 2015-06-11 M. Bazot , S. Bourguignon , J. Christensen-Dalsgaard

The generalized polynomial chaos method is applied to the Buckley-Leverett equation. We consider a spatially homogeneous domain modeled as a random field. The problem is projected onto stochastic basis functions which yields an extended…

Numerical Analysis · Mathematics 2016-08-24 Per Pettersson , Hamdi A. Tchelepi

In this paper, we study an optimal control problem for a nonlinear system of reaction-diffusion equations that constitutes a simplified and relaxed version of a thermodynamically consistent phase field model for tumor growth originally…

Optimization and Control · Mathematics 2020-08-25 Jürgen Sprekels , Fredi Tröltzsch