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In this work, we design and analyze an asymptotic preserving (AP), semi-implicit finite volume scheme for the scaled compressible isentropic Euler system with a singular pressure law known as the congestion pressure law. The congestion…

Numerical Analysis · Mathematics 2024-06-21 K. R. Arun , Amogh Krishnamurthy , Harihara Maharana

The study of uncertainty propagation poses a great challenge to design numerical solvers with high fidelity. Based on the stochastic Galerkin formulation, this paper addresses the idea and implementation of the first flux reconstruction…

Computational Physics · Physics 2021-12-14 Tianbai Xiao , Jonas Kusch , Julian Koellermeier , Martin Frank

In this paper we investigate some stochastic models for tumor-immune systems. To describe these models, we used a Wiener process, as the noise has a stabilization effect. Their dynamics are studied in terms of stochastic stability in the…

Dynamical Systems · Mathematics 2009-09-09 O. Chis , A. Sandru , D. Opris

In this work, we investigate the population dynamics of tumor cells under therapeutic pressure. Although drug treatment initially induces a reduction in tumor burden, treatment failure frequently occurs over time due to the emergence of…

Probability · Mathematics 2025-10-02 Kevin Leder , Zicheng Wang , Xuanming Zhang

We present a method for linear stability analysis of systems with parametric uncertainty formulated in the stochastic Galerkin framework. Specifically, we assume that for a model partial differential equation, the parameter is given in the…

Numerical Analysis · Mathematics 2026-01-14 Bedřich Sousedík , Kookjin Lee

This paper is concerned with a phase field system of Cahn-Hilliard type that is related to a tumor growth model and consists of three equations in terms of the variables order parameter, chemical potential and nutrient concentration. This…

Analysis of PDEs · Mathematics 2015-03-04 Pierluigi Colli , Gianni Gilardi , Elisabetta Rocca , Jürgen Sprekels

The paper focuses on the development of numerical methods for the compressible Euler equations. It is well-known that if the Mach number is small, the system becomes stiff and hence explicit schemes suffer from severe time-step…

Numerical Analysis · Mathematics 2026-04-30 Alina Chertock , Smadar Karni , Alexander Kurganov , Lorenzo Micalizzi

We consider a biphasic continuum model for avascular tumour growth in two spatial dimensions, in which a cell phase and a fluid phase follow conservation of mass and momentum. A limiting nutrient that follows a diffusion process controls…

Numerical Analysis · Mathematics 2020-10-21 Jerome Droniou , Jennifer A. Flegg , Gopikrishnan C. Remesan

In this paper, a two-dimensional model for the growth of multi-layer tumors is presented. The model consists of a free boundary problem for the tumor cell membrane and the tumor is supposed to grow or shrink due to cell proliferation or…

Analysis of PDEs · Mathematics 2013-06-11 Martin Kohlmann

In this paper, we will develop a class of high order asymptotic preserving (AP) discontinuous Galerkin (DG) methods for nonlinear time-dependent gray radiative transfer equations (GRTEs). Inspired by the work \cite{Peng2020stability}, in…

Numerical Analysis · Mathematics 2020-12-01 Tao Xiong , Wenjun Sun , Yi Shi , Peng Song

We study a stochastic phase-field model for tumor growth dynamics coupling a stochastic Cahn-Hilliard equation for the tumor phase parameter with a stochastic reaction-diffusion equation governing the nutrient proportion. We prove strong…

Analysis of PDEs · Mathematics 2021-01-19 Carlo Orrieri , Elisabetta Rocca , Luca Scarpa

We study a free boundary problem modelling the growth of non-necrotic tumors with fluid-like tissues. The fluid velocity satisfies Stokes equations with a source determined by the proliferation rate of tumor cells which depends on the…

Analysis of PDEs · Mathematics 2008-06-10 Junde Wu , Shangbin Cui

We study the porous medium equation (PME) in one space dimension in presence of additive non-conservative white noise, and interpreted as a stochastic growth equation for the height field of an interface. We predict the values of the two…

Statistical Mechanics · Physics 2026-03-05 Maximilien Bernard , Andrei A. Fedorenko , Pierre Le Doussal , Alberto Rosso

In this paper we present a method for estimating unknown parameters that appear on an avascular, spheric tumour growth model. The model for the tumour is based on nutrient driven growth of a continuum of live cells, whose birth and death…

Mathematical Physics · Physics 2012-09-14 D. A. Knopoff , D. R. Fernández , G. A. Torres , C. V. Turner

In this paper, we focus on constructing numerical schemes preserving the averaged energy evolution law for nonlinear stochastic wave equations driven by multiplicative noise. We first apply the compact finite difference method and the…

Numerical Analysis · Mathematics 2022-01-26 Jialin Hong , Baohui Hou , Liying Sun

Recent years have seen substantial advances in the development of biofunctional materials using synthetic polymers. The growing problem of elusive sequence-functionality relations for most biomaterials has driven researchers to seek more…

Quantitative Methods · Quantitative Biology 2022-07-06 Yun Zhou , Boying Gong , Tao Jiang , Ting Xu , Haiyan Huang

We analyze schemes based on a general Implicit-Explicit (IMEX) time discretization for the compressible Euler equations of gas dynamics, showing that they are asymptotic-preserving (AP) in the low Mach number limit. The analysis is carried…

Numerical Analysis · Mathematics 2025-10-23 Giuseppe Orlando , Luca Bonaventura

In this paper, we propose an adaptive approach, based on mesh refinement or parametric enrichment with polynomial degree adaption, for numerical solution of convection dominated equations with random input data. A parametric system emerged…

Numerical Analysis · Mathematics 2025-09-09 Pelin Çiloğlu , Hamdullah Yücel

The phenotypic plasticity of cancer cells has received special attention in recent years. Even though related models have been widely studied in terms of mathematical properties, a thorough statistical analysis on parameter estimation and…

Cell Behavior · Quantitative Biology 2017-12-05 Da Zhou , Shanjun Mao , Kaiyi Chen , Xiaofang Cao , Jie Hu

Smoothed Particle Hydrodynamics (SPH_ is a mesh-free Lagrangian method renowned for modeling large deformations and free-surface flows, yet classical formulations remain confined to deterministic systems. We introduce Stochastic SPH…

Computational Engineering, Finance, and Science · Computer Science 2026-05-14 Mridul Tiwari , Sawan Kumar , Md Rushdie Ibne Islam , Souvik Chakraborty