Optimal control of stochastic phase-field models related to tumor growth
Analysis of PDEs
2021-01-19 v1 Optimization and Control
Probability
Abstract
We study a stochastic phase-field model for tumor growth dynamics coupling a stochastic Cahn-Hilliard equation for the tumor phase parameter with a stochastic reaction-diffusion equation governing the nutrient proportion. We prove strong well-posedness of the system in a general framework through monotonicity and stochastic compactness arguments. We introduce then suitable controls representing the concentration of cytotoxic drugs administered in medical treatment and we analyze a related optimal control problem. We derive existence of an optimal strategy and deduce first-order necessary optimality conditions by studying the corresponding linearized system and the backward adjoint system.
Keywords
Cite
@article{arxiv.1908.00306,
title = {Optimal control of stochastic phase-field models related to tumor growth},
author = {Carlo Orrieri and Elisabetta Rocca and Luca Scarpa},
journal= {arXiv preprint arXiv:1908.00306},
year = {2021}
}
Comments
39 pages