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Deep learning-based methods are gaining traction in digital pathology, with an increasing number of publications and challenges that aim at easing the work of systematically and exhaustively analyzing tissue slides. These methods often…

Image and Video Processing · Electrical Eng. & Systems 2020-06-25 Ting-An Yen , Hung-Chun Hsu , Pushpak Pati , Maria Gabrani , Antonio Foncubierta-Rodríguez , Pau-Choo Chung

Magnetic Resonance Imaging (MRI) scans acquired from different scanners or institutions often suffer from domain shifts owing to variations in hardware, protocols, and acquisition parameters. This discrepancy degrades the performance of…

Computer Vision and Pattern Recognition · Computer Science 2026-01-21 Mohd Usama , Belal Ahmad , Faleh Menawer R Althiyabi

Nuclei segmentation is a fundamental task that is critical for various computational pathology applications including nuclei morphology analysis, cell type classification, and cancer grading. Conventional vision-based methods for nuclei…

Computer Vision and Pattern Recognition · Computer Science 2018-10-23 Faisal Mahmood , Daniel Borders , Richard Chen , Gregory N. McKay , Kevan J. Salimian , Alexander Baras , Nicholas J. Durr

Semantic segmentation has witnessed tremendous progress due to the proposal of various advanced network architectures. However, they are extremely hungry for delicate annotations to train, and the acquisition is laborious and unaffordable.…

Computer Vision and Pattern Recognition · Computer Science 2023-10-24 Lihe Yang , Xiaogang Xu , Bingyi Kang , Yinghuan Shi , Hengshuang Zhao

Fluorescence microscopy is an essential tool for the analysis of 3D subcellular structures in tissue. An important step in the characterization of tissue involves nuclei segmentation. In this paper, a two-stage method for segmentation of…

Image and Video Processing · Electrical Eng. & Systems 2020-01-10 David Joon Ho , Shuo Han , Chichen Fu , Paul Salama , Kenneth W. Dunn , Edward J. Delp

Modern optical microscopes are fully motorised; however, transforming them into truly smart systems requires real-time adjustment of acquisition settings in response to detected objects and dynamic biological events. At the core are…

Surgical tool segmentation in endoscopic images is an important problem: it is a crucial step towards full instrument pose estimation and it is used for integration of pre- and intra-operative images into the endoscopic view. While many…

Computer Vision and Pattern Recognition · Computer Science 2020-07-10 Daniil Pakhomov , Wei Shen , Nassir Navab

Accurate nuclei segmentation in microscopy whole slide images (WSIs) remains challenging due to variability in staining, imaging conditions, and tissue morphology. We propose CellGenNet, a knowledge distillation framework for robust…

Computer Vision and Pattern Recognition · Computer Science 2025-11-20 Srijan Ray , Bikesh K. Nirala , Jason T. Yustein , Sundaresh Ram

In this work we present a novel approach for unsupervised multi-graph matching, which applies to problems for which a Gaussian distribution of keypoint features can be assumed. We leverage cycle consistency as loss for self-supervised…

Computer Vision and Pattern Recognition · Computer Science 2026-03-04 Christoph Karg , Sebastian Stricker , Lisa Hutschenreiter , Bogdan Savchynskyy , Dagmar Kainmueller

Three-dimensional fluorescence microscopy often suffers from anisotropy, where the resolution along the axial direction is lower than that within the lateral imaging plane. We address this issue by presenting Dual-Cycle, a new framework for…

Image and Video Processing · Electrical Eng. & Systems 2022-09-26 Tomas Kerepecky , Jiaming Liu , Xue Wen Ng , David W. Piston , Ulugbek S. Kamilov

This paper presents Fd-CycleGAN, an image-to-image (I2I) translation framework that enhances latent representation learning to approximate real data distributions. Building upon the foundation of CycleGAN, our approach integrates Local…

Computer Vision and Pattern Recognition · Computer Science 2025-08-06 Shivangi Nigam , Adarsh Prasad Behera , Shekhar Verma , P. Nagabhushan

Obtaining large-scale medical data, annotated or unannotated, is challenging due to stringent privacy regulations and data protection policies. In addition, annotating medical images requires that domain experts manually delineate…

Computer Vision and Pattern Recognition · Computer Science 2025-05-16 Tushar Kataria , Shireen Y. Elhabian

Segmenting an image into its parts is a frequent preprocess for high-level vision tasks such as image editing. However, annotating masks for supervised training is expensive. Weakly-supervised and unsupervised methods exist, but they depend…

Computer Vision and Pattern Recognition · Computer Science 2022-10-11 Xingzhe He , Bastian Wandt , Helge Rhodin

Unpaired image-to-image translation of retinal images can efficiently increase the training dataset for deep-learning-based multi-modal retinal registration methods. Our method integrates a vessel segmentation network into the…

Image and Video Processing · Electrical Eng. & Systems 2023-06-06 Aline Sindel , Andreas Maier , Vincent Christlein

Annotating images with pixel-wise labels is a time-consuming and costly process. Recently, DatasetGAN showcased a promising alternative - to synthesize a large labeled dataset via a generative adversarial network (GAN) by exploiting a small…

Computer Vision and Pattern Recognition · Computer Science 2022-01-14 Daiqing Li , Huan Ling , Seung Wook Kim , Karsten Kreis , Adela Barriuso , Sanja Fidler , Antonio Torralba

Unsupervised and unpaired domain translation using generative adversarial neural networks, and more precisely CycleGAN, is state of the art for the stain translation of histopathology images. It often, however, suffers from the presence of…

Computer Vision and Pattern Recognition · Computer Science 2022-07-04 Nicolas Brieu , Felix J. Segerer , Ansh Kapil , Philipp Wortmann , Guenter Schmidt

Diffusion models (DMs) have enabled breakthroughs in image synthesis tasks but lack an intuitive interface for consistent image-to-image (I2I) translation. Various methods have been explored to address this issue, including mask-based…

Computer Vision and Pattern Recognition · Computer Science 2024-03-12 Sihan Xu , Ziqiao Ma , Yidong Huang , Honglak Lee , Joyce Chai

Nuclei segmentation is a fundamental task in histopathology image analysis. Typically, such segmentation tasks require significant effort to manually generate accurate pixel-wise annotations for fully supervised training. To alleviate such…

Computer Vision and Pattern Recognition · Computer Science 2020-07-13 Hui Qu , Pengxiang Wu , Qiaoying Huang , Jingru Yi , Zhennan Yan , Kang Li , Gregory M. Riedlinger , Subhajyoti De , Shaoting Zhang , Dimitris N. Metaxas

Unpaired image-to-image translation has broad applications in art, design, and scientific simulations. One early breakthrough was CycleGAN that emphasizes one-to-one mappings between two unpaired image domains via generative-adversarial…

Computer Vision and Pattern Recognition · Computer Science 2022-10-19 Dmitrii Torbunov , Yi Huang , Haiwang Yu , Jin Huang , Shinjae Yoo , Meifeng Lin , Brett Viren , Yihui Ren

Osteoclast cell image analysis plays a key role in osteoporosis research, but it typically involves extensive manual image processing and hand annotations by a trained expert. In the last few years, a handful of machine learning approaches…

Computer Vision and Pattern Recognition · Computer Science 2024-04-17 Sai Kumar Reddy Manne , Brendan Martin , Tyler Roy , Ryan Neilson , Rebecca Peters , Meghana Chillara , Christine W. Lary , Katherine J. Motyl , Michael Wan