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Cell image segmentation is usually implemented using fully supervised deep learning methods, which heavily rely on extensive annotated training data. Yet, due to the complexity of cell morphology and the requirement for specialized…

Computer Vision and Pattern Recognition · Computer Science 2024-05-06 Yu Zhu , Qiang Yang , Li Xu

Current semantic segmentation models typically require a substantial amount of manually annotated data, a process that is both time-consuming and resource-intensive. Alternatively, leveraging advanced text-to-image models such as Midjourney…

Computer Vision and Pattern Recognition · Computer Science 2025-07-08 Bo Gao , Jianhui Wang , Xinyuan Song , Yangfan He , Fangxu Xing , Tianyu Shi

Most state-of-the-art instance segmentation methods have to be trained on densely annotated images. While difficult in general, this requirement is especially daunting for biomedical images, where domain expertise is often required for…

Computer Vision and Pattern Recognition · Computer Science 2022-04-05 Adrian Wolny , Qin Yu , Constantin Pape , Anna Kreshuk

With the advancement of modern medicine and the development of technologies such as MRI, CT, and cellular analysis, it has become increasingly critical for clinicians to accurately interpret various diagnostic images. However, modern…

Image and Video Processing · Electrical Eng. & Systems 2025-06-05 Ruiming Min , Minghao Liu

Generative adversarial networks (GANs) have shown great success in applications such as image generation and inpainting. However, they typically require large datasets, which are often not available, especially in the context of prediction…

Machine Learning · Computer Science 2020-01-31 Daniel Stoller , Sebastian Ewert , Simon Dixon

The scarcity of pixel-level annotation is a prevalent problem in medical image segmentation tasks. In this paper, we introduce a novel regularization strategy involving interpolation-based mixing for semi-supervised medical image…

Image and Video Processing · Electrical Eng. & Systems 2022-02-04 Hritam Basak , Rajarshi Bhattacharya , Rukhshanda Hussain , Agniv Chatterjee

Nanomaterial research is becoming a vital area for energy, medicine, and materials science, and accurate analysis of the nanoparticle topology is essential to determine their properties. Unfortunately, the lack of high-quality annotated…

Computer Vision and Pattern Recognition · Computer Science 2025-05-26 Varun Ajith , Anindya Pal , Saumik Bhattacharya , Sayantari Ghosh

Cell and nucleus segmentation are fundamental tasks for quantitative bioimage analysis. Despite progress in recent years, biologists and other domain experts still require novel algorithms to handle increasingly large and complex real-world…

Computer Vision and Pattern Recognition · Computer Science 2024-08-29 Thibaut Goldsborough , Ben Philps , Alan O'Callaghan , Fiona Inglis , Leo Leplat , Andrew Filby , Hakan Bilen , Peter Bankhead

Unsupervised image-to-image translation methods such as CycleGAN learn to convert images from one domain to another using unpaired training data sets from different domains. Unfortunately, these approaches still require centrally collected…

Computer Vision and Pattern Recognition · Computer Science 2021-06-18 Joonyoung Song , Jong Chul Ye

Medical image segmentation - the prerequisite of numerous clinical needs - has been significantly prospered by recent advances in convolutional neural networks (CNNs). However, it exhibits general limitations on modeling explicit long-range…

Computer Vision and Pattern Recognition · Computer Science 2021-07-13 Yundong Zhang , Huiye Liu , Qiang Hu

CycleGAN provides a framework to train image-to-image translation with unpaired datasets using cycle consistency loss [4]. While results are great in many applications, the pixel level cycle consistency can potentially be problematic and…

Computer Vision and Pattern Recognition · Computer Science 2024-11-25 Tongzhou Wang , Yihan Lin

Cell segmentation is essential in biomedical research for analyzing cellular morphology and behavior. Deep learning methods, particularly convolutional neural networks (CNNs), have revolutionized cell segmentation by extracting intricate…

Image and Video Processing · Electrical Eng. & Systems 2024-08-27 Boyuan Peng , Jiaju Chen , P. Bilha Githinji , Ijaz Gul , Qihui Ye , Minjiang Chen , Peiwu Qin , Xingru Huang , Chenggang Yan , Dongmei Yu , Jiansong Ji , Zhenglin Chen

The most popular networks used for cell segmentation (e.g. Cellpose, Stardist, HoverNet,...) rely on a prediction of a distance map. It yields unprecedented accuracy but hinges on fully annotated datasets. This is a serious limitation to…

Computer Vision and Pattern Recognition · Computer Science 2025-08-26 Clément Cazorla , Nathanaël Munier , Renaud Morin , Pierre Weiss

We introduce a diffusion-based cross-domain image translator in the absence of paired training data. Unlike GAN-based methods, our approach integrates diffusion models to learn the image translation process, allowing for more coverable…

Computer Vision and Pattern Recognition · Computer Science 2026-01-30 Shilong Zou , Yuhang Huang , Renjiao Yi , Chenyang Zhu , Kai Xu

Background: Cell segmentation in bright-field histological slides is a crucial topic in medical image analysis. Having access to accurate segmentation allows researchers to examine the relationship between cellular morphology and clinical…

Despite that deep learning has achieved state-of-the-art performance for medical image segmentation, its success relies on a large set of manually annotated images for training that are expensive to acquire. In this paper, we propose an…

Image and Video Processing · Electrical Eng. & Systems 2021-01-01 Lu Wang , Dong Guo , Guotai Wang , Shaoting Zhang

Semantic segmentation, a crucial task in computer vision, often relies on labor-intensive and costly annotated datasets for training. In response to this challenge, we introduce FuseNet, a dual-stream framework for self-supervised semantic…

Computer Vision and Pattern Recognition · Computer Science 2023-11-23 Amirhossein Kazerouni , Sanaz Karimijafarbigloo , Reza Azad , Yury Velichko , Ulas Bagci , Dorit Merhof

Segmentation of nuclei regions from histological images is an important task for automated computer-aided analysis of histological images, particularly in the presence of impermissible color variation in the color appearance of stained…

Image and Video Processing · Electrical Eng. & Systems 2025-06-10 Suman Mahapatra , Pradipta Maji

Given the crucial role of microtubules for cell survival, many researchers have found success using microtubule-targeting agents in the search for effective cancer therapeutics. Understanding microtubule responses to targeted interventions…

Image and Video Processing · Electrical Eng. & Systems 2019-10-03 Hao-Chih Lee , Sarah T Cherng , Riccardo Miotto , Joel T Dudley

Spectral Clustering is a popular technique to split data points into groups, especially for complex datasets. The algorithms in the Spectral Clustering family typically consist of multiple separate stages (such as similarity matrix…

Machine Learning · Computer Science 2019-11-04 Yifei Wang , Rui Liu , Yong Chen , Hui Zhangs , Zhiwen Ye