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We present a unified mathematical approach to epidemiological models with parametric heterogeneity, i.e., to the models that describe individuals in the population as having specific parameter (trait) values that vary from one individuals…

Populations and Evolution · Quantitative Biology 2012-02-14 Artem S. Novozhilov

Human mobility, contact patterns, and their interplay are key aspects of our social behavior that shape the spread of infectious diseases across different regions. In the light of new evidence and data sets about these two elements,…

Physics and Society · Physics 2021-07-26 Wesley Cota , David Soriano-Paños , Alex Arenas , Silvio C. Ferreira , Jesús Gómez-Gardeñes

Capturing the structured mixing within a population is key to the reliable projection of infectious disease dynamics and hence informed control. Both heterogeneity in the number of contacts and age-structured mixing have been repeatedly…

Social and Information Networks · Computer Science 2026-03-17 Luke Murray Kearney , Emma L Davis , Matt J Keeling

These notes describe stochastic epidemics in a homogenous community. Our main concern is stochastic compartmental models (i.e. models where each individual belongs to a compartment, which stands for its status regarding the epidemic under…

Probability · Mathematics 2020-02-06 Tom Britton , Etienne Pardoux

Mathematical and computational modeling approaches are increasingly used as quantitative tools in the analysis and forecasting of infectious disease epidemics. The growing need for realism in addressing complex public health questions is…

We develop a generalized group-based epidemic model (GgroupEM) framework for any compartmental epidemic model (for example; susceptible-infected-susceptible, susceptible-infected-recovered, susceptible-exposed-infected-recovered). Here, a…

Physics and Society · Physics 2019-08-19 Sifat Afroj Moon , Faryad Darabi Sahneh , Caterina Scoglio

In this paper we first introduce the general stochastic epidemic model for the spread of infectious diseases. Then we give methods for inferring model parameters such as the basic reproduction number $R_0$ and vaccination coverage $v_c$…

Methodology · Statistics 2014-11-14 Tom Britton , Federica Giardina

Transmission models for infectious diseases are typically formulated in terms of dynamics between individuals or groups with processes such as disease progression or recovery for each individual captured phenomenologically, without…

An individual-based model of the infectious disease spread among the urban population is considered. A system of stochastic equations, which describes changes in quantities of four population groups, susceptible, exposed, infected…

Populations and Evolution · Quantitative Biology 2011-11-11 Vasiliy Leonenko

In this paper, we show how to modify a compartmental epidemic model, without changing the dimension, such that separable static heterogeneity is taken into account. The derivation is based on the Kermack-McKendrick renewal equation.

Populations and Evolution · Quantitative Biology 2022-11-24 Odo Diekmann , Hisashi Inaba

The duration, type and structure of connections between individuals in real-world populations play a crucial role in how diseases invade and spread. Here, we incorporate the aforementioned heterogeneities into a model by considering a…

Physics and Society · Physics 2018-04-05 Rosanna C Barnard , Istvan Z Kiss , Luc Berthouze , Joel C Miller

We introduce and analyze coupled, multi-strain epidemic models designed to simulate the emergence and dissemination of mutant (e.g. drug-resistant) pathogen strains. In particular, we investigate the mathematical and biological properties…

Populations and Evolution · Quantitative Biology 2017-05-10 Michael T. Meehan , Daniel G. Cocks , James M. Trauer , Emma S. McBryde

The recent pandemic emphasized the need to consider the role of human behavior in shaping epidemic dynamics. In particular, it is necessary to extend beyond the classical epidemiological structures to fully capture the interplay between the…

Dynamical Systems · Mathematics 2025-01-22 Leah LeJeune , Navid Ghaffarzadegan , Lauren Childs , Omar Saucedo

Computational models of infectious disease can be broadly categorized into two types: individual-based (Agent-based), or compartmental models. While compartmental models can be structured to separate distinct sectors of a population, they…

Populations and Evolution · Quantitative Biology 2021-12-14 Cameron Zachreson , Sheryl Chang , Nathan Harding , Mikhail Prokopenko

Stochastic modeling of disease dynamics has had a long tradition. Among the first epidemic models including a spatial structure in the form of local interactions is the contact process. In this article we investigate two extensions of the…

Probability · Mathematics 2007-05-23 L. Belhadji , N. Lanchier

The current survey paper concerns stochastic mathematical models for the spread of infectious diseases. It starts with the simplest setting of a homogeneous population in which a transmittable disease spreads during a short outbreak.…

Applications · Statistics 2018-01-30 Tom Britton

Individual contributions to the spread of an epidemic vary widely due to an individual's location in a social network and their intrinsic ability to spread or contract diseases. While the effect of heterogeneous population structure and…

Populations and Evolution · Quantitative Biology 2026-05-14 Abhay Gupta , Nicholas W. Landry

To forecast the time dynamics of an epidemic, we propose a discrete stochastic model that unifies and generalizes previous approaches to the subject. Viewing a given population of individuals or groups of individuals with given health state…

Understanding how internal community structure shapes the course of epidemics remains a fundamental challenge in modeling real-world populations. Standard metapopulation models often assume uniform mixing within communities, overlooking how…

Physics and Society · Physics 2025-11-07 Haoyang Qian , Malbor Asllani

The spreading dynamics of infectious diseases is influenced by individual behaviours, which are in turn affected by the level of awareness about the epidemic. Modelling the co-evolution of disease transmission and behavioural changes within…

Physics and Society · Physics 2026-02-27 Daniele Proverbio , Riccardo Tessarin , Giulia Giordano