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Computer simulations offer a robust toolset for exploring complex systems across various disciplines. A particularly impactful approach within this realm is Agent-Based Modeling (ABM), which harnesses the interactions of individual agents…

Artificial Intelligence · Computer Science 2023-12-19 Zengqing Wu , Run Peng , Xu Han , Shuyuan Zheng , Yixin Zhang , Chuan Xiao

Agent-based models have been employed to describe numerous processes in immunology. Simulations based on these types of models have been used to enhance our understanding of immunology and disease pathology. We review various agent-based…

Cell Behavior · Quantitative Biology 2017-12-05 Amy L. Bauer , Catherine A. A. Beauchemin , Alan S. Perelson

This work introduces a novel, modular, layered web based platform for managing machine learning experiments on grid-based High Performance Computing infrastructures. The coupling of the communication services offered by the grid, with an…

Distributed, Parallel, and Cluster Computing · Computer Science 2016-10-12 Chairi Kiourt , Dimitris Kalles

Simulations, although powerful in accurately replicating real-world systems, often remain inaccessible to non-technical users due to their complexity. Conversely, large language models (LLMs) provide intuitive, language-based interactions…

Computation and Language · Computer Science 2025-05-22 Jacob Kleiman , Kevin Frank , Joseph Voyles , Sindy Campagna

Usability testing is a fundamental research method that user experience (UX) researchers use to evaluate and iterate their new designs. But what about evaluating and iterating the usability testing study design itself? Recent advances in…

Computation and Language · Computer Science 2025-09-22 Yuxuan Lu , Bingsheng Yao , Hansu Gu , Jing Huang , Jessie Wang , Yang Li , Jiri Gesi , Qi He , Toby Jia-Jun Li , Dakuo Wang

Simulation of population dynamics is a central research theme in computational biology, which contributes to understanding the interactions between predators and preys. Conventional mathematical tools of this theme, however, are incapable…

Multiagent Systems · Computer Science 2020-02-11 Jun Yamada , John Shawe-Taylor , Zafeirios Fountas

Recommender systems are the cornerstone of today's information dissemination, yet a disconnect between offline metrics and online performance greatly hinders their development. Addressing this challenge, we envision a recommendation…

Information Retrieval · Computer Science 2024-11-11 An Zhang , Yuxin Chen , Leheng Sheng , Xiang Wang , Tat-Seng Chua

Existing large language model (LLM) agents for automating data science show promise, but they remain constrained by narrow task scopes, limited generalization across tasks and models, and over-reliance on state-of-the-art (SOTA) LLMs. We…

Computation and Language · Computer Science 2025-10-06 Ziming You , Yumiao Zhang , Dexuan Xu , Yiwei Lou , Yandong Yan , Wei Wang , Huaming Zhang , Yu Huang

Spreadsheets are central to real-world applications such as enterprise reporting, auditing, and scientific data management. Despite their ubiquity, existing large language model based approaches typically treat tables as plain text,…

Computation and Language · Computer Science 2026-04-15 Houxing Ren , Mingjie Zhan , Zimu Lu , Ke Wang , Yunqiao Yang , Haotian Hou , Hongsheng Li

Despite the remarkable progress of large language models (LLMs), the capabilities of standalone LLMs have begun to plateau when tackling real-world, complex tasks that require interaction with external tools and dynamic environments.…

Agent technology is a software paradigm that permits to implement large and complex distributed applications. In order to assist the development of multi-agent systems, agent-oriented methodologies (AOM) have been created in the last years…

Software Engineering · Computer Science 2014-03-13 Mohamed Garoui , Belhassen Mazigh , Béchir El Ayeb , Abderrafiaa Koukam

Building agents with adaptive behavior in cooperative tasks stands as a paramount goal in the realm of multi-agent systems. Current approaches to developing cooperative agents rely primarily on learning-based methods, whose policy…

This paper explains the design of a social network analysis framework, developed under DARPA's SocialSim program, with novel architecture that models human emotional, cognitive and social factors. Our framework is both theory and…

We introduce AgentSynth, a scalable and cost-efficient pipeline for automatically synthesizing high-quality tasks and trajectory datasets for generalist computer-use agents. Leveraging information asymmetry, AgentSynth constructs subtasks…

Computation and Language · Computer Science 2026-03-03 Jingxu Xie , Dylan Xu , Xuandong Zhao , Dawn Song

Agent-based models (ABMs) offer a powerful framework for understanding complex systems. However, their computational demands often become a significant barrier as the number of agents and complexity of the simulation increase. Traditional…

Multiagent Systems · Computer Science 2025-10-23 Steffen Fürst , Tim Conrad , Carlo Jaeger , Sarah Wolf

Embodied Artificial Intelligence (Embodied AI) emphasizes agents' ability to perceive, understand, and act in physical environments. Simulation platforms play a crucial role in advancing this field by enabling the validation and…

Robotics · Computer Science 2024-10-18 Kui Yang , Nieqing Cao , Yan Ding , Chao Chen

Large language model (LLM) agents are increasingly capable of automating components of machine learning development, yet existing biomedical benchmarks mainly focus on question answering, reasoning, and tool usage, or evaluate only narrow…

Computational Engineering, Finance, and Science · Computer Science 2026-05-18 Loka Li , Duzhen Zhang , Xingbo Du , Leonard Song , Zixiao Wang , Assanali Aukenov , Noel Thomas , Shakhnazar Sailaukan , Yonghan Yang , Feilong Chen , Jiahua Dong , Kun Zhang , Bin Zhang , Le Song

Large language models (LLMs) have demonstrated significant reasoning capabilities in scientific discovery but struggle to bridge the gap to physical execution in wet-labs. In these irreversible environments, probabilistic hallucinations are…

Artificial Intelligence · Computer Science 2026-05-19 Yuyang Liu , Jingya Wang , Liuzhenghao Lv , Yonghong Tian

Currently, agent-based simulation frameworks force the user to choose between simulations involving a large number of agents (at the expense of limited agent reasoning capability) or simulations including agents with increased reasoning…

Computer use agents represent an emerging area in artificial intelligence, aiming to operate computers autonomously to fulfill user tasks, attracting significant attention from both industry and academia. However, the performance of…

Artificial Intelligence · Computer Science 2026-01-23 Yuhao Cheng , Liang Tang , Shuxian Li , Yukang Huo , Tiaonan Duan , Kaer Huang , Yanzhe Jing , Yiqiang Yan