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The fundamental understanding of how cells physically interact with each other and their environment is key to understanding their organisation in living tissues. Over the past decades several computational methods have been developed to…

Quantitative Methods · Quantitative Biology 2026-01-22 Paul Van Liedekerke , Jiří Pešek , Kevin Alessandri , Dirk Drasdo

As LLM-based agents are increasingly deployed in real-life scenarios, existing benchmarks fail to capture their inherent complexity of handling extensive information, leveraging diverse resources, and managing dynamic user interactions. To…

Computation and Language · Computer Science 2025-10-20 Wei He , Yueqing Sun , Hongyan Hao , Xueyuan Hao , Zhikang Xia , Qi Gu , Chengcheng Han , Dengchang Zhao , Hui Su , Kefeng Zhang , Man Gao , Xi Su , Xiaodong Cai , Xunliang Cai , Yu Yang , Yunke Zhao

Recent advances in artificial intelligence have been driven by the presence of increasingly realistic and complex simulated environments. However, many of the existing environments provide either unrealistic visuals, inaccurate physics, low…

We introduce CFDagent, a zero-shot, multi-agent system that enables fully autonomous computational fluid dynamics (CFD) simulations from natural language prompts. CFDagent integrates three specialized LLM-driven agents: (i) the…

Fluid Dynamics · Physics 2025-11-13 Zhaoyue Xu , Long Wang , Chunyu Wang , Yixin Chen , Qingyong Luo , Hua-Dong Yao , Shizhao Wang , Guowei He

In this paper, our objective is to develop a multi-agent financial system that incorporates simulated trading, a technique extensively utilized by financial professionals. While current LLM-based agent models demonstrate competitive…

Artificial Intelligence · Computer Science 2025-10-07 Xiangyu Li , Yawen Zeng , Xiaofen Xing , Jin Xu , Xiangmin Xu

Just as computational simulations of atoms, molecules and cells have shaped the way we study the sciences, true-to-life simulations of human-like agents can be valuable tools for studying human behavior. We propose Humanoid Agents, a system…

Computation and Language · Computer Science 2023-10-10 Zhilin Wang , Yu Ying Chiu , Yu Cheung Chiu

Autonomous agent frameworks still struggle to reconcile long-term experiential learning with real-time, context-sensitive decision-making. In practice, this gap appears as static cognition, rigid workflow dependence, and inefficient context…

Artificial Intelligence · Computer Science 2026-03-11 Xiaoxing Wang , Ning Liao , Shikun Wei , Chen Tang , Feiyu Xiong

Bioscientists frequently seek to visualize the biological systems they have empirically characterized and reported in the literature. Realizing such visualizations requires biological structure modeling, an inherently complex process that…

Human-Computer Interaction · Computer Science 2026-05-20 Donggang Jia , Yunhai Wang , Ivan Viola

Despite the extensive use of the agent technology in the Supply Chain Management field, its integration with Advanced Planning and Scheduling (APS) tools still represents a promising field with several open research questions. Specifically,…

Multiagent Systems · Computer Science 2011-07-19 Luis Antonio de Santa-Eulalia , Sophie D'Amours , Jean-Marc Frayret

Agent-based modeling is a powerful simulation technique to understand the collective behavior and microscopic interaction in complex financial systems. Recently, the concept for determining the key parameters of the agent-based models from…

Statistical Finance · Quantitative Finance 2017-03-21 T. T. Chen , B. Zheng , Y. Li , X. F. Jiang

We introduce DABstep, a novel benchmark for evaluating AI agents on realistic multi-step data analysis tasks. DABstep comprises over 450 real-world challenges derived from a financial analytics platform, requiring models to combine…

Machine Learning · Computer Science 2025-07-01 Alex Egg , Martin Iglesias Goyanes , Friso Kingma , Andreu Mora , Leandro von Werra , Thomas Wolf

Training capable Large Language Model (LLM) agents is critically bottlenecked by the high cost and static nature of real-world interaction data. We address this by introducing GenEnv, a framework that establishes a difficulty-aligned…

Computation and Language · Computer Science 2025-12-24 Jiacheng Guo , Ling Yang , Peter Chen , Qixin Xiao , Yinjie Wang , Xinzhe Juan , Jiahao Qiu , Ke Shen , Mengdi Wang

Interactive multi-agent simulation algorithms are used to compute the trajectories and behaviors of different entities in virtual reality scenarios. However, current methods involve considerable parameter tweaking to generate plausible…

Graphics · Computer Science 2018-12-04 Jiaping Ren , Wei Xiang , Yangxi Xiao , Ruigang Yang , Dinesh Manocha , Xiaogang Jin

As cosmological simulations and their associated software become increasingly complex, physicists face the challenge of searching through vast amounts of literature and user manuals to extract simulation parameters from dense academic…

Instrumentation and Methods for Astrophysics · Physics 2025-07-21 Xiaowen Zhang , Zhenyu Bi , Patrick Lachance , Xuan Wang , Tiziana Di Matteo , Rupert A. C. Croft

Agents based on large language models have shown great potential in accelerating scientific discovery by leveraging their rich background knowledge and reasoning capabilities. In this paper, we introduce BioDiscoveryAgent, an agent that…

Artificial Intelligence · Computer Science 2025-03-11 Yusuf Roohani , Andrew Lee , Qian Huang , Jian Vora , Zachary Steinhart , Kexin Huang , Alexander Marson , Percy Liang , Jure Leskovec

Force field-based molecular dynamics (MD) simulations are indispensable for probing the structure, dynamics, and functions of biomolecular systems, including proteins and protein-ligand complexes. Despite their broad utility in drug…

Artificial Intelligence · Computer Science 2025-12-12 Salomé Guilbert , Cassandra Masschelein , Jeremy Goumaz , Bohdan Naida , Philippe Schwaller

Agent technology is a software paradigm that permits to implement large and complex distributed applications. In order to assist analyzing, conception and development or implementation phases of multi-agent systems, we've tried to present a…

Multiagent Systems · Computer Science 2012-04-10 Sara Maalal , Malika Addou

The grand aim of having a single robot that can manipulate arbitrary objects in diverse settings is at odds with the paucity of robotics datasets. Acquiring and growing such datasets is strenuous due to manual efforts, operational costs,…

Robotics · Computer Science 2023-09-06 Homanga Bharadhwaj , Jay Vakil , Mohit Sharma , Abhinav Gupta , Shubham Tulsiani , Vikash Kumar

Recent progress in large language models (LLMs) has enabled substantial advances in solving mathematical problems. However, existing benchmarks often fail to reflect the complexity of real-world problems, which demand open-ended,…

Artificial Intelligence · Computer Science 2025-05-22 Cheng Qian , Hongyi Du , Hongru Wang , Xiusi Chen , Yuji Zhang , Avirup Sil , Chengxiang Zhai , Kathleen McKeown , Heng Ji

Developing trustworthy multi-agent systems for practical applications is challenging due to the complicated communication of situational awareness (SA) among agents. This paper showcases a novel efficient and easy-to-use software framework…

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