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Translational medicine turns underspecified development goals into evidence synthesis that must combine literature, trials, patents, and quantitative multi-omics analysis while preserving identifiers, uncertainty, and retrievable…

Computer simulations have become a very powerful tool for scientific research. Given the vast complexity that comes with many open scientific questions, a purely analytical or experimental approach is often not viable. For example,…

Neural and Evolutionary Computing · Computer Science 2016-07-12 Roman Bauer , Lukas Breitwieser , Alberto Di Meglio , Leonard Johard , Marcus Kaiser , Marco Manca , Manuel Mazzara , Max Talanov

Replicating existing agent-based models poses significant challenges, particularly for those new to the field. This article presents an all-encompassing guide to re-implementing agent-based models, encompassing vital concepts such as…

Multiagent Systems · Computer Science 2024-05-08 Önder Gürcan , Timo Szczepanska , Patrycja Antosz

Agent Based Models are very popular in a number of different areas. For example, they have been used in a range of domains ranging from modeling of tumor growth, immune systems, molecules to models of social networks, crowds and computer…

Multiagent Systems · Computer Science 2017-08-09 Muaz A. Niazi , Amir Hussain , Mario Kolberg

Immersive rooms are increasingly popular augmented reality systems that support multi-agent interactions within a virtual world. However, despite extensive content creation and technological developments, insights about perceptually-driven…

Human-Computer Interaction · Computer Science 2025-12-22 Jerry M. Huang , Stefan T. Radev

Agent-based modeling is a paradigm of modeling dynamic systems of interacting agents that are individually governed by specified behavioral rules. Training a model of such agents to produce an emergent behavior by specification of the…

Machine Learning · Computer Science 2019-10-11 Karan K. Budhraja , Hang Gao , Tim Oates

Emergency departments worldwide face rising patient volumes, workforce shortages, and variability in triage decisions that threaten the delivery of timely and accurate care. Current triage methods rely primarily on vital signs, routine…

Quantitative Methods · Quantitative Biology 2025-10-21 Kerem Delikoyun , Qianyu Chen , Win Sen Kuan , John Tshon Yit Soong , Matthew Edward Cove , Oliver Hayden

Dermatological diagnosis requires integrating fine-grained visual perception with expert clinical knowledge. Although Multimodal Large Language Models (MLLMs) facilitate interactive medical image analysis, their application in dermatology…

Computer Vision and Pattern Recognition · Computer Science 2026-05-15 Yize Liu , Siyuan Yan , Ming Hu , Lie Ju , Xieji Li , Feilong Tang , Wei Feng , Zongyuan Ge

The believable simulation of multi-user behavior is crucial for understanding complex social systems. Recently, large language models (LLMs)-based AI agents have made significant progress, enabling them to achieve human-like intelligence…

Artificial Intelligence · Computer Science 2024-12-16 Yijun Liu , Wu Liu , Xiaoyan Gu , Yong Rui , Xiaodong He , Yongdong Zhang

The agent-based modeling and simulation (ABMS) paradigm has been used to analyze, reproduce, and predict phenomena related to many application areas. Although there are many agent-based platforms that support simulation development, they…

Artificial Intelligence · Computer Science 2020-06-17 Fernando Santos , Ingrid Nunes , Ana L. C. Bazzan

The advent of artificial intelligence has led to a growing emphasis on data-driven modeling in macroeconomics, with agent-based modeling (ABM) emerging as a prominent bottom-up simulation paradigm. In ABM, agents (e.g., households, firms)…

Artificial Intelligence · Computer Science 2024-05-27 Nian Li , Chen Gao , Mingyu Li , Yong Li , Qingmin Liao

Modelling and computational methods have been essential in advancing quantitative science, especially in the past two decades with the availability of vast amount of complex, voluminous, and heterogeneous data. In particular, there has been…

Multiagent Systems · Computer Science 2020-07-09 Affan Shoukat , Seyed M. Moghadas

In decision support systems, it is essential to get a candidate solution fast, even if it means resorting to an approximation. This constraint introduces a scalability requirement with regard to the kind of heuristics which can be used in…

Multiagent Systems · Computer Science 2014-05-22 D. Krzywicki , Ł. Faber , A. Byrski , M. Kisiel-Dorohinicki

Large reasoning models have demonstrated strong problem-solving abilities, yet real-world tasks often require external tools and long-horizon interactions. Existing agent frameworks typically follow predefined workflows, which limit…

Artificial Intelligence · Computer Science 2026-02-06 Xiaoxi Li , Wenxiang Jiao , Jiarui Jin , Guanting Dong , Jiajie Jin , Yinuo Wang , Hao Wang , Yutao Zhu , Ji-Rong Wen , Yuan Lu , Zhicheng Dou

Agent-based modelling is a valuable approach for systems whose behaviour is driven by the interactions between distinct entities. They have shown particular promise as a means of modelling crowds of people in streets, public transport…

Multiagent Systems · Computer Science 2020-04-30 Nick Malleson , Kevin Minors , Le-Minh Kieu , Jonathan A. Ward , Andrew A. West , Alison Heppenstall

In the accelerating era of human-instructed visual content creation, diffusion models have demonstrated remarkable generative potential. Yet their deployment is constrained by a dual bottleneck: semantic ambiguity in diverse prompts and the…

Computer Vision and Pattern Recognition · Computer Science 2026-01-21 Jie Qin , Jie Wu , Weifeng Chen , Yueming Lyu

The discovery of novel small molecule drugs remains a critical scientific challenge with far-reaching implications for treating diseases and advancing human health. Traditional drug development--especially for small molecule…

Biomolecules · Quantitative Biology 2025-04-01 Bowen Gao , Yanwen Huang , Yiqiao Liu , Wenxuan Xie , Wei-Ying Ma , Ya-Qin Zhang , Yanyan Lan

We introduce AgentWorld, an interactive simulation platform for developing household mobile manipulation capabilities. Our platform combines automated scene construction that encompasses layout generation, semantic asset placement, visual…

Robotics · Computer Science 2025-08-14 Yizheng Zhang , Zhenjun Yu , Jiaxin Lai , Cewu Lu , Lei Han

Spreadsheets are ubiquitous across the World Wide Web, playing a critical role in enhancing work efficiency across various domains. Large language model (LLM) has been recently attempted for automatic spreadsheet manipulation but has not…

Artificial Intelligence · Computer Science 2025-03-04 Yibin Chen , Yifu Yuan , Zeyu Zhang , Yan Zheng , Jinyi Liu , Fei Ni , Jianye Hao , Hangyu Mao , Fuzheng Zhang

Large language models(LLMs) are now used to power complex multi-turn agentic workflows. Existing systems run agentic inference by loosely assembling isolated components: an LLM inference engine (e.g., vLLM) and a tool orchestrator (e.g.,…

Operating Systems · Computer Science 2026-03-12 Hao Kang , Ziyang Li , Xinyu Yang , Weili Xu , Yinfang Chen , Junxiong Wang , Beidi Chen , Tushar Krishna , Chenfeng Xu , Simran Arora
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