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Radiation therapy (RT) is widely employed in the clinic for the treatment of head and neck (HaN) cancers. An essential step of RT planning is the accurate segmentation of various organs-at-risks (OARs) in HaN CT images. Nevertheless,…

Image and Video Processing · Electrical Eng. & Systems 2021-09-28 Zijie Chen , Cheng Li , Junjun He , Jin Ye , Diping Song , Shanshan Wang , Lixu Gu , Yu Qiao

A high-precision manipulation task, such as needle threading, is challenging. Physiological studies have proposed connecting low-resolution peripheral vision and fast movement to transport the hand into the vicinity of an object, and using…

Robotics · Computer Science 2025-05-23 Heecheol Kim , Yoshiyuki Ohmura , Yasuo Kuniyoshi

Radiotherapy treatment planning remains a time-intensive iterative process requiring expert intervention in commercial treatment planning system (TPS). While machine learning approaches have demonstrated promise, most remain depedent on…

We present an error-controlled mesh refinement procedure for needle insertion simulation and apply it to the simulation of electrode implantation for deep brain stimulation, including brain shift. Our approach enables to control the error…

Computational Engineering, Finance, and Science · Computer Science 2018-11-20 Huu Phuoc Bui , Satyendra Tomar , Hadrien Courtecuisse , Michel Audette , Stéphane Cotin , Stéphane P. A. Bordas

Skin dose in radiotherapy is a key issue for reducing patient side effects, but dose calculations in this high-gradient region remains a challenge. To support radiation therapists and medical physicist in their decisions, a computational…

Purpose: This study quantifies the variation in dose-volume histogram (DVH) and normal tissue complication probability (NTCP) metrics for head-and-neck (HN) cancer patients when alternative organ-at-risk (OAR) delineations are used for…

To develop an automated workflow for rectal cancer three-dimensional conformal radiotherapy treatment planning that combines deep-learning(DL) aperture predictions and forward-planning algorithms. We designed an algorithm to automate the…

We present an efficient deep learning approach for the challenging task of tumor segmentation in multisequence MR images. In recent years, Convolutional Neural Networks (CNN) have achieved state-of-the-art performances in a large variety of…

Computer Vision and Pattern Recognition · Computer Science 2018-07-24 Pawel Mlynarski , Hervé Delingette , Antonio Criminisi , Nicholas Ayache

Radiation therapy treatment planning can be viewed as an iterative hyperparameter tuning process to balance conflicting clinical goals. In this work, we investigated the performance of modern Bayesian Optimization (BO) methods on automated…

Medical Physics · Physics 2023-02-15 Qingying Wang , Ruoxi Wang , Jiacheng Liu , Fan Jiang , Haizhen Yue , Yi Du , Hao Wu

In recent advancements in proton therapy, MR-based treatment planning is gaining momentum to minimize additional radiation exposure compared to traditional CT-based methods. This transition highlights the critical need for accurate MR-to-CT…

Medical Physics · Physics 2024-07-02 Muheng Li , Xia Li , Sairos Safai , Damien Weber , Antony Lomax , Ye Zhang

Medical images come in high resolutions. A high resolution is vital for finding malignant tissues at an early stage. Yet, this resolution presents a challenge in terms of modeling long range dependencies. Shallow transformers eliminate this…

Computer Vision and Pattern Recognition · Computer Science 2022-08-15 Ahmed Taha , Yen Nhi Truong Vu , Brent Mombourquette , Thomas Paul Matthews , Jason Su , Sadanand Singh

The scarcity of richly annotated medical images is limiting supervised deep learning based solutions to medical image analysis tasks, such as localizing discriminatory radiomic disease signatures. Therefore, it is desirable to leverage…

Computer Vision and Pattern Recognition · Computer Science 2019-06-10 Saeid Asgari Taghanaki , Mohammad Havaei , Tess Berthier , Francis Dutil , Lisa Di Jorio , Ghassan Hamarneh , Yoshua Bengio

Purpose: To develop a machine learning-based, 3D dose prediction methodology for Gamma Knife (GK) radiosurgery. The methodology accounts for cases involving targets of any number, size, and shape. Methods: Data from 322 GK treatment plans…

Medical Physics · Physics 2023-01-09 Binghao Zhang , Aaron Babier , Timothy C. Y. Chan , Mark Ruschin

Fast and accurate dose predictions are one of the bottlenecks in treatment planning for microbeam radiation therapy (MRT). In this paper, we propose a machine learning (ML) model based on a 3D U-Net. Our approach predicts separately the…

This work introduces a new latent diffusion model to generate high-quality 3D chest CT scans conditioned on 3D anatomical masks. The method synthesizes volumetric images of size 256x256x256 at 1 mm isotropic resolution using a single…

Computer Vision and Pattern Recognition · Computer Science 2025-10-22 Anna Oliveras , Roger Marí , Rafael Redondo , Oriol Guardià , Ana Tost , Bhalaji Nagarajan , Carolina Migliorelli , Vicent Ribas , Petia Radeva

Three-dimensional (3D) images, such as CT, MRI, and PET, are common in medical imaging applications and important in clinical diagnosis. Semantic ambiguity is a typical feature of many medical image labels. It can be caused by many factors,…

Image and Video Processing · Electrical Eng. & Systems 2022-09-19 Lin Wang , Xiufen Ye , Donghao Zhang , Wanji He , Lie Ju , Xin Wang , Wei Feng , Kaimin Song , Xin Zhao , Zongyuan Ge

It is possible to find the optimized radiation dose per session for a radiotherapy (RT) treatment, using a population dynamics model. This has already been done in a previous work for a protocol with 30 sessions and a fixed dose per…

The objective of this paper is to significantly reduce the manual workload required from medical professionals in complex 3D segmentation tasks that cannot be yet fully automated. For instance, in radiotherapy planning, organs at risk must…

Purpose: Many planning methods for high dose rate (HDR) brachytherapy treatment planning require an iterative approach. A set of computational parameters are hypothesized that will give a dose plan that meets dosimetric criteria. A dose…

Medical Physics · Physics 2016-11-25 Timmy Siauw , Adam Cunha , Alper Atamturk , I-Chow Hsu , Jean Pouliot , Ken Goldberg

Accurate multi-needle localization in intraoperative CT images is crucial for optimizing seed placement in pelvic seed implant brachytherapy. However, this task is challenging due to poor image contrast and needle adhesion. This paper…

Computer Vision and Pattern Recognition · Computer Science 2026-05-21 Zhuo Xiao , Fugen Zhou , Jingjing Wang , Chongyu He , Bo Liu , Haitao Sun , Zhe Ji , Yuliang Jiang , Junjie Wang , Qiuwen Wu