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Purpose: To improve target coverage and reduce the dose in the surrounding organs-at-risks (OARs), we developed an image-guided treatment method based on a precomputed library of treatment plans controlled and delivered in real-time.…

Medical Physics · Physics 2022-11-02 Valentin Hamaide , Kevin Souris , Damien Dasnoy , Francois Glineur , Benoit Macq

In this contribution, a software system for computer-aided position planning of miniplates to treat facial bone defects is proposed. The intra-operatively used bone plates have to be passively adapted on the underlying bone contours for…

Computer Vision and Pattern Recognition · Computer Science 2017-08-22 Jan Egger , Jürgen Wallner , Markus Gall , Xiaojun Chen , Katja Schwenzer-Zimmerer , Knut Reinbacher , Dieter Schmalstieg

The segmentation of diseases is a popular topic explored by researchers in the field of machine learning. Brain tumors are extremely dangerous and require the utmost precision to segment for a successful surgery. Patients with tumors…

Image and Video Processing · Electrical Eng. & Systems 2022-04-05 Sanskriti Singh

The two-dimensional nature of mammography makes estimation of the overall breast density challenging, and estimation of the true patient-specific radiation dose impossible. Digital breast tomosynthesis (DBT), a pseudo-3D technique, is now…

In robotic radiation therapy, high-energy photon beams from different directions are directed at a target within the patient. Target motion can be tracked by robotic ultrasound and then compensated by synchronous beam motion. However,…

Computational Engineering, Finance, and Science · Computer Science 2024-03-29 Lars Beckers , Stefan Gerlach , Ole Lübke , Alexander Schlaefer , Sibylle Schupp

Purpose: LATTICE, a form of spatially fractionated radiation therapy that delivers high-dose peaks and low-dose valleys within the target, has been clinically utilized for treating bulky tumors. However, its application to…

Medical Physics · Physics 2025-09-08 Nimita Shinde , Weijie Zhang , Yuting Lin , Hao Gao

The clinical management of breast cancer depends on an accurate understanding of the tumor and its anatomical context to adjacent tissues and landmark structures. This context may be provided by semantic segmentation methods; however,…

Image and Video Processing · Electrical Eng. & Systems 2023-11-29 Arda Pekis , Vignesh Kannan , Evandros Kaklamanos , Anu Antony , Snehal Patel , Tyler Earnest

We present a method of directly optimizing on deviations in clinical goal values in radiation therapy treatment planning. Using a new mathematical framework in which metrics derived from the dose-volume histogram are regarded as functionals…

Medical Physics · Physics 2021-09-07 Tianfang Zhang , Rasmus Bokrantz , Jimmy Olsson

3D head avatars built with neural implicit volumetric representations have achieved unprecedented levels of photorealism. However, the computational cost of these methods remains a significant barrier to their widespread adoption,…

Computer Vision and Pattern Recognition · Computer Science 2024-04-03 Ziqian Bai , Feitong Tan , Sean Fanello , Rohit Pandey , Mingsong Dou , Shichen Liu , Ping Tan , Yinda Zhang

Usually, lesions are not isolated but are associated with the surrounding tissues. For example, the growth of a tumour can depend on or infiltrate into the surrounding tissues. Due to the pathological nature of the lesions, it is…

Image and Video Processing · Electrical Eng. & Systems 2022-10-12 Lin Wang , Xiufen Ye , Donghao Zhang , Wanji He , Lie Ju , Yi Luo , Huan Luo , Xin Wang , Wei Feng , Kaimin Song , Xin Zhao , Zongyuan Ge

Radiotherapy (RT) planning is complex, subjective, and time-intensive. Advances with artificial intelligence (AI) promise to improve its precision and efficiency, but progress is often limited by the scarcity of large, standardized…

Patient-specific bone models are essential for designing surgical guides and preoperative planning, as they enable the visualization of intricate anatomical structures. However, traditional CT-based approaches for creating bone models are…

Protontherapy is hadrontherapy fastest-growing modality and a pillar in the battle against cancer. Hadrontherapy superiority lies in its inverted depth-dose profile, hence tumour-confined irradiation. Protons, however, lack distinct…

Radiation therapy (RT) is a vital part of treatment for head and neck cancer, where accurate segmentation of gross tumor volume (GTV) is essential for effective treatment planning. This study investigates the use of pre-RT tumor regions and…

Computer Vision and Pattern Recognition · Computer Science 2025-03-05 Jintao Ren , Kim Hochreuter , Mathis Ersted Rasmussen , Jesper Folsted Kallehauge , Stine Sofia Korreman

Rendering photorealistic and dynamically moving human heads is crucial for ensuring a pleasant and immersive experience in AR/VR and video conferencing applications. However, existing methods often struggle to model challenging facial…

Computer Vision and Pattern Recognition · Computer Science 2026-02-20 Cong Wang , Di Kang , Yan-Pei Cao , Linchao Bao , Ying Shan , Song-Hai Zhang

Radiation therapy is an effective and widely accepted form of treatment for many types of cancer that requires extensive computerized planning. Unfortunately, current treatment planning systems have limited or no visual aid that combines…

Graphics · Computer Science 2018-11-30 Felix G. Hamza-Lup , Ivan Sopin , Omar Zeidan

Purpose: Diffusion MRI has shown promise for breast cancer screening, lesion characterization,and treatment response monitoring without contrast agents, but further translation is constraint by the gradient performance of conventional…

Medical Physics · Physics 2026-05-12 Gerrit Arends , Edwin Versteeg , Feng Jia , Dennis Klomp , Maxim Zaitsev , Sebastian Littin , Chantal Tax

Early identification of head and neck cancer (HNC) patients who would experience significant anatomical change during radiotherapy (RT) is important to optimize patient clinical benefit and treatment resources. This study aims to assess the…

Computer Vision and Pattern Recognition · Computer Science 2024-05-24 Meixu Chen , Kai Wang , Michael Dohopolski , Howard Morgan , David Sher , Jing Wang

In medicine, needles are frequently used to deliver treatments to subsurface targets or to take tissue samples from the inside of an organ. Current clinical practice is to insert needles under image guidance or haptic feedback, although…

Systems and Control · Electrical Eng. & Systems 2020-04-29 Antje Rogalla , Sascha Lehmann , Maximilian Neidhardt , Johanna Sprenger , Marcel Bengs , Alexander Schlaefer , Sibylle Schupp

Neutron computed tomography (nCT) is a 3D characterization technique used to image the internal morphology or chemical composition of samples in biology and materials sciences. A typical workflow involves placing the sample in the path of a…

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