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Large language models (LLMs) are increasingly deployed in settings where the available context is incomplete or degraded. We argue that an LLM generating answers under incomplete context can be viewed as an implicit imputer, and evaluated…

Machine Learning · Statistics 2026-05-14 Stef van Buuren

This paper introduces MedExQA, a novel benchmark in medical question-answering, to evaluate large language models' (LLMs) understanding of medical knowledge through explanations. By constructing datasets across five distinct medical…

Computation and Language · Computer Science 2024-07-04 Yunsoo Kim , Jinge Wu , Yusuf Abdulle , Honghan Wu

Large language models (LLMs) are prone to generating factually incorrect outputs. Recent work has applied conformal prediction to provide uncertainty estimates and statistical guarantees for the factuality of LLM generations. However,…

Computation and Language · Computer Science 2026-04-16 Aleksandr Rubashevskii , Dzianis Piatrashyn , Preslav Nakov , Maxim Panov

This study aims to address the pervasive challenge of quantifying uncertainty in large language models (LLMs) without logit-access. Conformal Prediction (CP), known for its model-agnostic and distribution-free features, is a desired…

Computation and Language · Computer Science 2024-04-05 Jiayuan Su , Jing Luo , Hongwei Wang , Lu Cheng

While large language models (LLMs) perform strongly on diverse tasks, their trustworthiness is limited by erratic behavior that is unfaithful to their internal knowledge. In particular, LLMs often fail on multiple-choice questions (MCQs)…

Computation and Language · Computer Science 2026-02-05 Yoonah Park , Haesung Pyun , Yohan Jo

Current Large Language Models (LLMs) benchmarks are often based on open-ended or close-ended QA evaluations, avoiding the requirement of human labor. Close-ended measurements evaluate the factuality of responses but lack expressiveness.…

Large language models (LLMs) produce outputs with varying levels of uncertainty, and, just as often, varying levels of correctness; making their practical reliability far from guaranteed. To quantify this uncertainty, we systematically…

Computation and Language · Computer Science 2025-10-24 Christian Hobelsberger , Theresa Winner , Andreas Nawroth , Oliver Mitevski , Anna-Carolina Haensch

Premature closure, or committing to a conclusion before sufficient information is available, is a recognized contributor to diagnostic error but remains underexamined in large language models (LLMs). We define LLM premature closure as…

Computation and Language · Computer Science 2026-05-15 Rebecca Handler , Suhana Bedi , Nigam Shah

Large Language Models (LLMs) show promise for natural language generation in healthcare, but risk hallucinating factually incorrect information. Deploying LLMs for medical question answering necessitates reliable uncertainty estimation (UE)…

Computation and Language · Computer Science 2024-07-12 Jiaxin Wu , Yizhou Yu , Hong-Yu Zhou

Large Language Models (LLMs) have the potential of facilitating the development of Artificial Intelligence technology to assist medical experts for interactive decision support, which has been demonstrated by their competitive performances…

Computation and Language · Computer Science 2024-11-12 Iñigo Alonso , Maite Oronoz , Rodrigo Agerri

While Large Language Models have transformed how we interact with AI systems, they suffer from a critical flaw: they confidently generate false information that sounds entirely plausible. This hallucination problem has become a major…

Artificial Intelligence · Computer Science 2025-10-28 Piyushkumar Patel

Large language models (LLMs) have demonstrated impressive capabilities in natural language understanding and generation, but the quality bar for medical and clinical applications is high. Today, attempts to assess models' clinical knowledge…

Large language models (LLMs) need reliable test-time control of hallucinations. Existing conformal methods for LLMs typically provide only \emph{marginal} guarantees and rely on a single global threshold, which can under-cover hard prompts,…

Machine Learning · Computer Science 2026-03-31 Kai Ye , Qingtao Pan , Shuo Li

Large Reasoning Models (LRMs) have recently demonstrated significant improvements in complex reasoning. While quantifying generation uncertainty in LRMs is crucial, traditional methods are often insufficient because they do not provide…

Artificial Intelligence · Computer Science 2026-04-16 Yangyi Li , Chenxu Zhao , Mengdi Huai

Empowered by vast internal knowledge reservoir, the new generation of large language models (LLMs) demonstrate untapped potential to tackle medical tasks. However, there is insufficient effort made towards summoning up a synergic effect…

Computation and Language · Computer Science 2025-05-23 Kexin Shang , Chia-Hsuan Chang , Christopher C. Yang

Large Language Models (LLMs) have shown significant advances in text generation but often lack the reliability needed for autonomous deployment in high-stakes domains like healthcare, law, and finance. Existing approaches rely on external…

Artificial Intelligence · Computer Science 2024-11-12 Ninad Naik

Multiple Choice Question (MCQ) tests are among the most used methods for evaluating large language models (LLMs). Besides checking the correctness of the selected answer, evaluations often consider the model's confidence through the…

Computation and Language · Computer Science 2026-05-05 Tairan Fu , Javier Conde , Gonzalo Martínez , María Grandury , Pedro Reviriego

Large Language Models (LLMs) like LLaMA, Mistral, and Gemma are increasingly used in decision-critical domains such as healthcare, law, and finance, yet their reliability remains uncertain. They often make overconfident errors, degrade…

Computation and Language · Computer Science 2026-01-01 Rohit Kumar Salla , Manoj Saravanan , Shrikar Reddy Kota

With appropriate data selection and training techniques, Large Language Models (LLMs) have demonstrated exceptional success in various medical examinations and multiple-choice questions. However, the application of LLMs in medical dialogue…

Computation and Language · Computer Science 2024-03-12 Jiageng Wu , Xian Wu , Yefeng Zheng , Jie Yang

Multilingual pre-trained Large Language Models (LLMs) are incredibly effective at Question Answering (QA), a core task in Natural Language Understanding, achieving high accuracies on several multilingual benchmarks. However, little is known…

Computation and Language · Computer Science 2024-04-16 Yahan Yang , Soham Dan , Dan Roth , Insup Lee