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We present a novel framework addressing a critical vulnerability in Large Language Models (LLMs): the prevalence of factual inaccuracies within intermediate reasoning steps despite correct final answers. This phenomenon poses substantial…

Computation and Language · Computer Science 2025-08-05 Rui Jiao , Yue Zhang , Jinku Li

Visual question answering (VQA) in medical imaging aims to support clinical diagnosis by automatically interpreting complex imaging data in response to natural language queries. Existing studies typically rely on distinct visual and textual…

Computer Vision and Pattern Recognition · Computer Science 2025-07-08 Yuanhe Tian , Chen Su , Junwen Duan , Yan Song

Self-detection for Large Language Models (LLMs) seeks to evaluate the trustworthiness of the LLM's output by leveraging its own capabilities, thereby alleviating the issue of output hallucination. However, existing self-detection approaches…

Computation and Language · Computer Science 2024-09-30 Moxin Li , Wenjie Wang , Fuli Feng , Fengbin Zhu , Qifan Wang , Tat-Seng Chua

The MEDIQA-CORR 2024 shared task aims to assess the ability of Large Language Models (LLMs) to identify and correct medical errors in clinical notes. In this study, we evaluate the capability of general LLMs, specifically GPT-3.5 and GPT-4,…

Computation and Language · Computer Science 2024-05-29 Aryo Pradipta Gema , Chaeeun Lee , Pasquale Minervini , Luke Daines , T. Ian Simpson , Beatrice Alex

Large Language Models (LLMs) still face challenges when dealing with complex reasoning tasks, often resulting in hallucinations, which limit the practical application of LLMs. To alleviate this issue, this paper proposes a new method that…

Artificial Intelligence · Computer Science 2024-11-26 Zhihua Duan , Jialin Wang

Safety alignment in large language models (LLMs) is primarily evaluated under open-ended generation, where models can mitigate risk by refusing to respond. In contrast, many real-world applications place LLMs in structured decision-making…

Computation and Language · Computer Science 2026-04-21 Yuheng Chen , Zhiyu Wu , Bowen Cheng , Tetsuro Takahashi

Large Language Models (LLMs) and Large Reasoning Models (LRMs) offer transformative potential for high-stakes domains like finance and law, but their tendency to hallucinate, generating factually incorrect or unsupported content, poses a…

Artificial Intelligence · Computer Science 2026-01-16 Ahmad Pesaranghader , Erin Li

We develop a new approach to multi-label conformal prediction in which we aim to output a precise set of promising prediction candidates with a bounded number of incorrect answers. Standard conformal prediction provides the ability to adapt…

Machine Learning · Computer Science 2022-02-16 Adam Fisch , Tal Schuster , Tommi Jaakkola , Regina Barzilay

As large language models (LLMs) are increasingly deployed in risk-sensitive applications such as real-world open-ended question answering (QA), ensuring the trustworthiness of their outputs has become critical. Existing selective conformal…

Artificial Intelligence · Computer Science 2026-02-17 Qingni Wang , Yue Fan , Xin Eric Wang

The extraction of lung lesion information from clinical and medical imaging reports is crucial for research on and clinical care of lung-related diseases. Large language models (LLMs) can be effective at interpreting unstructured text in…

Computation and Language · Computer Science 2024-11-18 Diya Li , Asim Kadav , Aijing Gao , Rui Li , Richard Bourgon

Large Language Models (LLMs) exhibit strong performance across various natural language processing (NLP) tasks but remain vulnerable to hallucinations, generating factually incorrect or misleading outputs. Uncertainty estimation, often…

Machine Learning · Computer Science 2025-11-12 Manh Nguyen , Sunil Gupta , Hung Le

The application of the Multi-modal Large Language Models (MLLMs) in medical clinical scenarios remains underexplored. Previous benchmarks only focus on the capacity of the MLLMs in medical visual question-answering (VQA) or report…

Computation and Language · Computer Science 2024-08-19 Hongcheng Liu , Yusheng Liao , Siqv Ou , Yuhao Wang , Heyang Liu , Yanfeng Wang , Yu Wang

Users often assume that large language models (LLMs) share their cognitive alignment of context and intent, leading them to omit critical information in question-answering (QA) and produce ambiguous queries. Responses based on misaligned…

Computation and Language · Computer Science 2025-09-12 Zongxi Li , Yang Li , Haoran Xie , S. Joe Qin

Visualizations play a pivotal role in daily communication in an increasingly data-driven world. Research on multimodal large language models (MLLMs) for automated chart understanding has accelerated massively, with steady improvements on…

Computation and Language · Computer Science 2026-04-20 Jonathan Tonglet , Tinne Tuytelaars , Marie-Francine Moens , Iryna Gurevych

Large Language Models (LLMs) hold promise in addressing complex medical problems. However, while most prior studies focus on improving accuracy and reasoning abilities, a significant bottleneck in developing effective healthcare agents lies…

Computation and Language · Computer Science 2025-10-06 Weikang Qiu , Tinglin Huang , Ryan Rullo , Yucheng Kuang , Ali Maatouk , S. Raquel Ramos , Rex Ying

Advancements in Large Language Models (LLMs) and their increasing use in medical question-answering necessitate rigorous evaluation of their reliability. A critical challenge lies in hallucination, where models generate plausible yet…

Computation and Language · Computer Science 2025-02-21 Shrey Pandit , Jiawei Xu , Junyuan Hong , Zhangyang Wang , Tianlong Chen , Kaidi Xu , Ying Ding

Large Language Models (LLMs) are known to hallucinate, whereby they generate plausible but inaccurate text. This phenomenon poses significant risks in critical applications, such as medicine or law, necessitating robust hallucination…

Computation and Language · Computer Science 2024-10-23 Benedict Aaron Tjandra , Muhammed Razzak , Jannik Kossen , Kunal Handa , Yarin Gal

With the advancement of Large Language Models (LLMs), their application in Software Quality Assurance (SQA) has increased. However, the current focus of these applications is predominantly on ChatGPT. There remains a gap in understanding…

Software Engineering · Computer Science 2024-09-04 Ratnadira Widyasari , David Lo , Lizi Liao

We present a refined approach to biomedical question-answering (QA) services by integrating large language models (LLMs) with Multi-BERT configurations. By enhancing the ability to process and prioritize vast amounts of complex biomedical…

Computation and Language · Computer Science 2024-10-18 Cheng Qian , Xianglong Shi , Shanshan Yao , Yichen Liu , Fengming Zhou , Zishu Zhang , Junaid Akram , Ali Braytee , Ali Anaissi

As ChatGPT and GPT-4 spearhead the development of Large Language Models (LLMs), more researchers are investigating their performance across various tasks. But more research needs to be done on the interpretability capabilities of LLMs, that…

Computation and Language · Computer Science 2023-10-27 Dongfang Li , Jindi Yu , Baotian Hu , Zhenran Xu , Min Zhang
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