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Affine image registration is a cornerstone of medical image analysis. While classical algorithms can achieve excellent accuracy, they solve a time-consuming optimization for every image pair. Deep-learning (DL) methods learn a function that…

Image and Video Processing · Electrical Eng. & Systems 2024-07-15 Malte Hoffmann , Andrew Hoopes , Douglas N. Greve , Bruce Fischl , Adrian V. Dalca

Presented are two techniques that are designed to help streamline the discretization of complex vascular geometries within the numerical modeling process. The first method integrates multiple software tools into a single pipeline which can…

Fluid Dynamics · Physics 2025-12-05 Kevin Garner , Fotis Drakopoulos , Chander Sadasivan , Nikos Chrisochoides

Creating tetrahedral meshes with anatomically accurate surfaces is critically important for a wide range of model-based neuroimaging modalities. However, computationally efficient brain meshing algorithms and software are greatly lacking.…

Medical Physics · Physics 2017-08-31 Anh Phong Tran , Qianqian Fang

Numerical simulations rely on constructing accurate and detailed models to produce reliable results - a task that is often challenging. This task becomes notably more difficult when the model is of the human brain. We create an anatomically…

Computational Engineering, Finance, and Science · Computer Science 2024-10-11 Andy Huynh , Benjamin Zwick , Mostafa Jamshidian , Michael Halle , Adam Wittek , Karol Miller

Brain mapping research in most neuroanatomical laboratories relies on conventional processing techniques, which often introduce histological artifacts such as tissue tears and tissue loss. In this paper we present techniques and algorithms…

Graphics · Computer Science 2017-12-29 Nitin Agarwal , Xiangmin Xu , Gopi Meenakshisundaram

We present a keypoint-based foundation model for general purpose brain MRI registration, based on the recently-proposed KeyMorph framework. Our model, called BrainMorph, serves as a tool that supports multi-modal, pairwise, and scalable…

Computer Vision and Pattern Recognition · Computer Science 2025-06-10 Alan Q. Wang , Rachit Saluja , Heejong Kim , Xinzi He , Adrian Dalca , Mert R. Sabuncu

We present MultiMorph, a fast and efficient method for constructing anatomical atlases on the fly. Atlases capture the canonical structure of a collection of images and are essential for quantifying anatomical variability across…

Computer Vision and Pattern Recognition · Computer Science 2025-04-02 S. Mazdak Abulnaga , Andrew Hoopes , Neel Dey , Malte Hoffmann , Marianne Rakic , Bruce Fischl , John Guttag , Adrian Dalca

Computational simulations using methods such as the finite element (FE) method rely on high-quality meshes for achieving accurate results. This study introduces a method for creating a high-quality hexahedral mesh using the Open Anatomy…

Computational Engineering, Finance, and Science · Computer Science 2024-02-23 Andy Trung Huynh , Benjamin Zwick , Michael Halle , Adam Wittek , Karol Miller

Non-rigid cortical registration is an important and challenging task due to the geometric complexity of the human cortex and the high degree of inter-subject variability. A conventional solution is to use a spherical representation of…

Image and Video Processing · Electrical Eng. & Systems 2020-07-28 Jieyu Cheng , Adrian V. Dalca , Bruce Fischl , Lilla Zollei

In the field of medical image analysis, image registration is a crucial technique. Despite the numerous registration models that have been proposed, existing methods still fall short in terms of accuracy and interpretability. In this paper,…

Computer Vision and Pattern Recognition · Computer Science 2024-10-25 Jiaofen Nan , Gaodeng Fan , Kaifan Zhang , Chen Zhao , Fubao Zhu , Weihua Zhou

We introduce "PatchMorph," an new stochastic deep learning algorithm tailored for unsupervised 3D brain image registration. Unlike other methods, our method uses compact patches of a constant small size to derive solutions that can combine…

Computer Vision and Pattern Recognition · Computer Science 2024-10-28 Henrik Skibbe , Michal Byra , Akiya Watakabe , Tetsuo Yamamori , Marco Reisert

Deformable image registration is crucial for aligning medical images in a nonlinear fashion across different modalities, allowing for precise spatial correspondence between varying anatomical structures. This paper presents NestedMorph, a…

Image and Video Processing · Electrical Eng. & Systems 2024-12-11 Gurucharan Marthi Krishna Kumar , Janine Mendola , Amir Shmuel

The removal of non-brain signal from magnetic resonance imaging (MRI) data, known as skull-stripping, is an integral component of many neuroimage analysis streams. Despite their abundance, popular classical skull-stripping methods are…

Image and Video Processing · Electrical Eng. & Systems 2022-07-27 Andrew Hoopes , Jocelyn S. Mora , Adrian V. Dalca , Bruce Fischl , Malte Hoffmann

In the context of computer assist surgical techniques, a new elastic registration method of 3D meshes is presented. In our applications, one mesh is a high density mesh (30000 vertexes), the second is a low density one (1000 vertexes).…

Medical Physics · Physics 2016-08-16 Maxime Berar , Michel Desvignes , Gérard Bailly , Yohan Payan

Neuroscientists have devoted significant effort into the creation of standard brain reference atlases for high-throughput registration of anatomical regions of interest. However, variability in brain size and form across individuals poses a…

Computer Vision and Pattern Recognition · Computer Science 2019-06-10 Asim Iqbal , Romesa Khan , Theofanis Karayannis

Image registration is the process of bringing different images into a common coordinate system - a technique widely used in various applications of computer vision, such as remote sensing, image retrieval, and, most commonly, medical…

This paper presents a novel predictive model, MetaMorph, for metamorphic registration of images with appearance changes (i.e., caused by brain tumors). In contrast to previous learning-based registration methods that have little or no…

Computer Vision and Pattern Recognition · Computer Science 2023-03-10 Jian Wang , Jiarui Xing , Jason Druzgal , William M. Wells , Miaomiao Zhang

Finite Element mesh generation remains an important issue for patient specific biomechanical modeling. While some techniques make automatic mesh generation possible, in most cases, manual mesh generation is preferred for better control over…

Medical Physics · Physics 2010-07-28 Marek Bucki , Claudio Lobos , Yohan Payan

Finite Element mesh generation remains an important issue for patient specific biomechanical modeling. While some techniques make automatic mesh generation possible, in most cases, manual mesh generation is preferred for better control over…

Medical Physics · Physics 2010-05-31 Marek Bucki , Claudio Lobos , Yohan Payan

Image registration is a fundamental medical image analysis task. Ideally, registration should focus on aligning semantically corresponding voxels, i.e., the same anatomical locations. However, existing methods often optimize similarity…

Computer Vision and Pattern Recognition · Computer Science 2024-02-27 Lin Tian , Zi Li , Fengze Liu , Xiaoyu Bai , Jia Ge , Le Lu , Marc Niethammer , Xianghua Ye , Ke Yan , Daikai Jin
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