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Purpose: Segmentation of organs-at-risk (OARs) is a bottleneck in current radiation oncology pipelines and is often time consuming and labor intensive. In this paper, we propose an atlas-based semi-supervised registration algorithm to…

Computer Vision and Pattern Recognition · Computer Science 2019-11-26 Charles Huang , Masoud Badiei , Hyunseok Seo , Ming Ma , Xiaokun Liang , Dante Capaldi , Michael Gensheimer , Lei Xing

We present KeyMorph, a deep learning-based image registration framework that relies on automatically detecting corresponding keypoints. State-of-the-art deep learning methods for registration often are not robust to large misalignments, are…

Computer Vision and Pattern Recognition · Computer Science 2023-09-04 Alan Q. Wang , Evan M. Yu , Adrian V. Dalca , Mert R. Sabuncu

Performing volumetric image processing directly within the browser, particularly with medical data, presents unprecedented challenges compared to conventional backend tools. These challenges arise from limitations inherent in browser…

Machine Learning · Computer Science 2023-10-26 Mohamed Masoud , Pratyush Reddy , Farfalla Hu , Sergey Plis

We present 2 statistical models of the skull and mandible built upon an elastic registration method of 3D meshes. The aim of this work is to relate degrees of freedom of skull anatomy, as static relations are of main interest for…

Medical Physics · Physics 2016-08-16 Maxime Berar , Michel Desvignes , Gérard Bailly , Yohan Payan

Registration is a fundamental task in medical image analysis which can be applied to several tasks including image segmentation, intra-operative tracking, multi-modal image alignment, and motion analysis. Popular registration tools such as…

Computer Vision and Pattern Recognition · Computer Science 2019-10-07 Wentao Zhu , Andriy Myronenko , Ziyue Xu , Wenqi Li , Holger Roth , Yufang Huang , Fausto Milletari , Daguang Xu

Deformable registration consists of finding the best dense correspondence between two different images. Many algorithms have been published, but the clinical application was made difficult by the high calculation time needed to solve the…

Computer Vision and Pattern Recognition · Computer Science 2021-11-25 Théo Estienne , Maria Vakalopoulou , Enzo Battistella , Theophraste Henry , Marvin Lerousseau , Amaury Leroy , Nikos Paragios , Eric Deutsch

The effects of the aortic geometry on its mechanics and blood flow, and subsequently on aortic pathologies, remain largely unexplored. The main obstacle lies in obtaining patient-specific aorta models, an extremely difficult procedure in…

Deformable templates, or atlases, are images that represent a prototypical anatomy for a population, and are often enhanced with probabilistic anatomical label maps. They are commonly used in medical image analysis for population studies…

Computer Vision and Pattern Recognition · Computer Science 2025-11-18 Marianne Rakic , Andrew Hoopes , S. Mazdak Abulnaga , Mert R. Sabuncu , John V. Guttag , Adrian V. Dalca

Most existing algorithms for automatic 3D morphometry of human brain MRI scans are designed for data with near-isotropic voxels at approximately 1 mm resolution, and frequently have contrast constraints as well - typically requiring T1…

Image and Video Processing · Electrical Eng. & Systems 2020-12-25 Juan Eugenio Iglesias , Benjamin Billot , Yael Balbastre , Azadeh Tabari , John Conklin , Daniel C. Alexander , Polina Golland , Brian L. Edlow , Bruce Fischl

Magnetic Resonance Imaging (MRI) of the fetal brain has become a key tool for studying brain development in vivo. Yet, its assessment remains challenging due to variability in brain maturation, imaging protocols, and uncertain estimates of…

Image and Video Processing · Electrical Eng. & Systems 2025-10-09 Johannes Tischer , Patric Kienast , Marlene Stümpflen , Gregor Kasprian , Georg Langs , Roxane Licandro

Image registration between histology and magnetic resonance imaging (MRI) is a challenging task due to differences in structural content and contrast. Too thick and wide specimens cannot be processed all at once and must be cut into smaller…

Computer Vision and Pattern Recognition · Computer Science 2017-08-29 Jonas Pichat , Juan Eugenio Iglesias , Sotiris Nousias , Tarek Yousry , Sebastien Ourselin , Marc Modat

Deformable registration of magnetic resonance images between patients with brain tumors and healthy subjects has been an important tool to specify tumor geometry through location alignment and facilitate pathological analysis. Since tumor…

Image and Video Processing · Electrical Eng. & Systems 2021-01-19 Xiaofeng Liu , Fangxu Xing , Chao Yang , C. -C. Jay Kuo , Georges ElFakhri , Jonghye Woo

This paper presents DeepFLASH, a novel network with efficient training and inference for learning-based medical image registration. In contrast to existing approaches that learn spatial transformations from training data in the high…

Image and Video Processing · Electrical Eng. & Systems 2020-04-07 Jian Wang , Miaomiao Zhang

The ability to register image data to a common coordinate system is a critical feature of virtually all imaging studies that require multiple subject analysis, combining single subject data from multiple modalities, or both. However, in…

Computer Vision and Pattern Recognition · Computer Science 2017-06-19 Vitaly L. Galinsky , Lawrence R. Frank

Every year, thousands of people suffer from skull damage and require personalized implants to fill the cranial cavity. Unfortunately, the waiting time for reconstruction surgery can extend to several weeks or even months, especially in less…

Image and Video Processing · Electrical Eng. & Systems 2024-11-27 Marek Wodzinski , Mateusz Daniol , Daria Hemmerling

We aim to reduce the tedious nature of developing and evaluating methods for aligning PET-CT scans from multiple patient visits. Current methods for registration rely on correspondences that are created manually by medical experts with 3D…

Computer Vision and Pattern Recognition · Computer Science 2019-11-26 Teaghan O'Briain , Kyong Hwan Jin , Hongyoon Choi , Erika Chin , Magdalena Bazalova-Carter , Kwang Moo Yi

Representation learning on large-scale unstructured volumetric and surface meshes poses significant challenges in neuroimaging, especially when models must incorporate diverse vertex-level morphometric descriptors, such as cortical…

Computer Vision and Pattern Recognition · Computer Science 2026-04-08 Yujian Xiong , Mohammad Farazi , Yanxi Chen , Wenhui Zhu , Xuanzhao Dong , Natasha Lepore , Yi Su , Raza Mushtaq , Stephen Foldes , Andrew Yang , Yalin Wang

Whole brain segmentation on a structural magnetic resonance imaging (MRI) is essential in non-invasive investigation for neuroanatomy. Historically, multi-atlas segmentation (MAS) has been regarded as the de facto standard method for whole…

Computer Vision and Pattern Recognition · Computer Science 2018-06-06 Yuankai Huo , Zhoubing Xu , Katherine Aboud , Prasanna Parvathaneni , Shunxing Bao , Camilo Bermudez , Susan M. Resnick , Laurie E. Cutting , Bennett A. Landman

Due to the scarcity of labeled data, self-supervised learning (SSL) has gained much attention in 3D medical image segmentation, by extracting semantic representations from unlabeled data. Among SSL strategies, Masked image modeling (MIM)…

Computer Vision and Pattern Recognition · Computer Science 2024-07-18 Yuheng Li , Tianyu Luan , Yizhou Wu , Shaoyan Pan , Yenho Chen , Xiaofeng Yang

Segmentation of brain magnetic resonance images (MRI) is crucial for the analysis of the human brain and diagnosis of various brain disorders. The drawbacks of time-consuming and error-prone manual delineation procedures are aimed to be…

Computer Vision and Pattern Recognition · Computer Science 2022-05-20 Can Taylan Sari , Sila Kurugol , Onur Afacan , Simon K. Warfield