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Finding low dimensional representation of data from long-timescale trajectories of biomolecular processes such as protein-folding or ligand-receptor binding is of fundamental importance and kinetic models such as Markov modeling have proven…

Computational Physics · Physics 2024-06-19 Mahdi Ghorbani , Samarjeet Prasad , Jeffery B. Klauda , Bernard R. Brooks

Modeling disease progression is crucial for improving the quality and efficacy of clinical diagnosis and prognosis, but it is often hindered by a lack of longitudinal medical image monitoring for individual patients. To address this…

Computer Vision and Pattern Recognition · Computer Science 2024-11-20 Xu Cao , Kaizhao Liang , Kuei-Da Liao , Tianren Gao , Wenqian Ye , Jintai Chen , Zhiguang Ding , Jianguo Cao , James M. Rehg , Jimeng Sun

In the last few years, deep neural networks opened the doors for big advances in novel view synthesis. Many of these approaches are based on a (coarse) proxy geometry obtained by structure from motion algorithms. Small deficiencies in this…

Computer Vision and Pattern Recognition · Computer Science 2023-11-09 Linus Franke , Darius Rückert , Laura Fink , Matthias Innmann , Marc Stamminger

Obtaining large pre-trained models that can be fine-tuned to new tasks with limited annotated samples has remained an open challenge for medical imaging data. While pre-trained deep networks on ImageNet and vision-language foundation models…

Computer Vision and Pattern Recognition · Computer Science 2023-11-21 Duy M. H. Nguyen , Hoang Nguyen , Nghiem T. Diep , Tan N. Pham , Tri Cao , Binh T. Nguyen , Paul Swoboda , Nhat Ho , Shadi Albarqouni , Pengtao Xie , Daniel Sonntag , Mathias Niepert

In the field of multimodal chain-of-thought (CoT) reasoning, existing approaches predominantly rely on reasoning on pure language space, which inherently suffers from language bias and is largely confined to math or science domains. This…

Computer Vision and Pattern Recognition · Computer Science 2026-05-04 Jiacong Wang , Zijian Kang , Haochen Wang , Haiyong Jiang , Jiawen Li , Bohong Wu , Ya Wang , Jiao Ran , Xiao Liang , Chao Feng , Jun Xiao

The semantic segmentation task in pathology plays an indispensable role in assisting physicians in determining the condition of tissue lesions. With the proposal of Segment Anything Model (SAM), more and more foundation models have seen…

Image and Video Processing · Electrical Eng. & Systems 2024-09-05 Mingya Zhang , Liang Wang , Zhihao Chen , Yiyuan Ge , Xianping Tao

Computational Pathology CPath is an interdisciplinary science that augments developments of computational approaches to analyze and model medical histopathology images. The main objective for CPath is to develop infrastructure and workflows…

AI tools in pathology have improved screening throughput, standardized quantification, and revealed prognostic patterns that inform treatment. However, adoption remains limited because most systems still lack the human-readable reasoning…

Artificial Intelligence · Computer Science 2025-11-18 Yunqi Hong , Johnson Kao , Liam Edwards , Nein-Tzu Liu , Chung-Yen Huang , Alex Oliveira-Kowaleski , Cho-Jui Hsieh , Neil Y. C. Lin

Radiologists rely on anatomical understanding to accurately delineate pathologies, yet most current deep learning approaches use pure pattern recognition and ignore the anatomical context in which pathologies develop. To narrow this gap, we…

Computer Vision and Pattern Recognition · Computer Science 2025-08-06 Keyi Li , Alexander Jaus , Jens Kleesiek , Rainer Stiefelhagen

Radiology is a vital and complex component of modern clinical workflow and covers many tasks. Recently, vision-language (VL) foundation models in medicine have shown potential in processing multimodal information, offering a unified…

Computer Vision and Pattern Recognition · Computer Science 2024-09-25 Xiaohong Liu , Guoxing Yang , Yulin Luo , Jiaji Mao , Xiang Zhang , Ming Gao , Shanghang Zhang , Jun Shen , Guangyu Wang

Pathological diagnosis is vital for determining disease characteristics, guiding treatment, and assessing prognosis, relying heavily on detailed, multi-scale analysis of high-resolution whole slide images (WSI). However, existing large…

Computer Vision and Pattern Recognition · Computer Science 2025-05-19 Shengxuming Zhang , Weihan Li , Tianhong Gao , Jiacong Hu , Haoming Luo , Xiuming Zhang , Jing Zhang , Mingli Song , Zunlei Feng

We apply convolutional neural networks (ConvNets) to the task of distinguishing pathological from normal EEG recordings in the Temple University Hospital EEG Abnormal Corpus. We use two basic, shallow and deep ConvNet architectures recently…

Machine Learning · Computer Science 2018-01-15 Robin Tibor Schirrmeister , Lukas Gemein , Katharina Eggensperger , Frank Hutter , Tonio Ball

Accurate prediction of cancer progression remains a challenge due to the high heterogeneity of molecular omics data across patients. While biologically informed models have improved the interpretability of these predictions, a persistent…

Machine Learning · Computer Science 2026-04-21 Koushik Howlader , Md Tauhidul Islam , Wei Le

Medical image segmentation models struggle with rare abnormalities due to scarce annotated pathological data. We propose DiffAug a novel framework that combines textguided diffusion-based generation with automatic segmentation validation to…

Computer Vision and Pattern Recognition · Computer Science 2025-08-26 Maham Nazir , Muhammad Aqeel , Francesco Setti

Automated pathology segmentation remains a valuable diagnostic tool in clinical practice. However, collecting training data is challenging. Semi-supervised approaches by combining labelled and unlabelled data can offer a solution to data…

Image and Video Processing · Electrical Eng. & Systems 2020-09-09 Haochuan Jiang , Agisilaos Chartsias , Xinheng Zhang , Giorgos Papanastasiou , Scott Semple , Mark Dweck , David Semple , Rohan Dharmakumar , Sotirios A. Tsaftaris

The inability to interpret the model prediction in semantically and visually meaningful ways is a well-known shortcoming of most existing computer-aided diagnosis methods. In this paper, we propose MDNet to establish a direct multimodal…

Computer Vision and Pattern Recognition · Computer Science 2017-07-11 Zizhao Zhang , Yuanpu Xie , Fuyong Xing , Mason McGough , Lin Yang

Radiology Report Generation (RRG) is a critical step toward automating healthcare workflows, facilitating accurate patient assessments, and reducing the workload of medical professionals. Despite recent progress in Large Medical…

Computer Vision and Pattern Recognition · Computer Science 2026-03-16 Sarosij Bose , Ravi K. Rajendran , Biplob Debnath , Konstantinos Karydis , Amit K. Roy-Chowdhury , Srimat Chakradhar

Perivascular spaces(PVSs) form a central component of the brain\'s waste clearance system, the glymphatic system. These structures are visible on MRI images, and their morphology is associated with aging and neurological disease. Manual…

Interpretable deep learning models have received widespread attention in the field of image recognition. Due to the unique multi-instance learning of medical images and the difficulty in identifying decision-making regions, many…

Computer Vision and Pattern Recognition · Computer Science 2023-12-05 Yitao Peng , Lianghua He , Die Hu , Yihang Liu , Longzhen Yang , Shaohua Shang

Convolutional neural network (CNN), in particular the Unet, is a powerful method for medical image segmentation. To date Unet has demonstrated state-of-art performance in many complex medical image segmentation tasks, especially under the…

Image and Video Processing · Electrical Eng. & Systems 2019-10-31 Wenjun Yan , Yuanyuan Wang , Shengjia Gu , Lu Huang , Fuhua Yan , Liming Xia , Qian Tao