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Cell instance segmentation is a fundamental task in digital pathology with broad clinical applications. Recently, vision foundation models, which are predominantly based on Vision Transformers (ViTs), have achieved remarkable success in…

Computer Vision and Pattern Recognition · Computer Science 2025-04-02 Yang Yang , Xijie Xu , Yixun Zhou , Jie Zheng

Nucleus segmentation is an important analysis task in digital pathology. However, methods for automatic segmentation often struggle with new data from a different distribution, requiring users to manually annotate nuclei and retrain…

Image and Video Processing · Electrical Eng. & Systems 2025-06-03 Titus Griebel , Anwai Archit , Constantin Pape

In recent years, foundation models such as CLIP, DINO,and CONCH have demonstrated remarkable domain generalization and unsupervised feature extraction capabilities across diverse imaging tasks. However, systematic and independent…

Computer Vision and Pattern Recognition · Computer Science 2026-02-24 Lavish Ramchandani , Aashay Tinaikar , Dev Kumar Das , Rohit Garg , Tijo Thomas

Ensuring accessible pedestrian navigation requires reasoning about both semantic and spatial aspects of complex urban scenes, a challenge that existing Large Vision-Language Models (LVLMs) struggle to meet. Although these models can…

Computer Vision and Pattern Recognition · Computer Science 2026-03-12 Rafi Ibn Sultan , Hui Zhu , Xiangyu Zhou , Chengyin Li , Prashant Khanduri , Marco Brocanelli , Dongxiao Zhu

Pathology foundation models (PFMs) have emerged as a core approach for learning transferable representations from whole slide images (WSIs), and they are typically benchmarked through downstream clinical endpoints. While such task level…

Computer Vision and Pattern Recognition · Computer Science 2026-05-26 Bokai Zhao , Yiyang Zhang , Yuanchi Zhu , Hanqing Chao , Long Bai , Tai Ma , Minfeng Xu , Ming Song , Tianzi Jiang

Recent advancements in Vision Language Models (VLMs) have demonstrated remarkable promise in generating visually grounded responses. However, their application in the medical domain is hindered by unique challenges. For instance, most VLMs…

Computer Vision and Pattern Recognition · Computer Science 2025-02-19 Lingxiao Luo , Bingda Tang , Xuanzhong Chen , Rong Han , Ting Chen

Vision GNN (ViG) demonstrates superior performance by representing images as graph structures, providing a more natural way to capture irregular semantic patterns beyond traditional grid or sequence-based representations. To efficiently…

Computer Vision and Pattern Recognition · Computer Science 2025-05-27 Zixiang Ai , Zichen Liu , Jiahuan Zhou

Driven by the recent advances in deep learning methods and, in particular, by the development of modern self-supervised learning algorithms, increased interest and efforts have been devoted to build foundation models (FMs) for medical…

Computer Vision and Pattern Recognition · Computer Science 2024-04-24 kaiko. ai , Nanne Aben , Edwin D. de Jong , Ioannis Gatopoulos , Nicolas Känzig , Mikhail Karasikov , Axel Lagré , Roman Moser , Joost van Doorn , Fei Tang

Instance segmentation is an important task for biomedical and biological image analysis. Due to the complicated background components, the high variability of object appearances, numerous overlapping objects, and ambiguous object…

Computer Vision and Pattern Recognition · Computer Science 2021-02-24 Dongnan Liu , Donghao Zhang , Yang Song , Heng Huang , Weidong Cai

Tumor region segmentation is an essential task for the quantitative analysis of digital pathology. Recently presented deep neural networks have shown state-of-the-art performance in various image-segmentation tasks. However, because of the…

Computer Vision and Pattern Recognition · Computer Science 2023-07-04 Seonghui Min , Won-Ki Jeong

NLP-based computer vision models, particularly vision transformers, have been shown to outperform CNN models in many imaging tasks. However, most digital pathology artificial-intelligence models are based on CNN architectures, probably…

Computation and Language · Computer Science 2023-02-22 Min Cen , Xingyu Li , Bangwei Guo , Jitendra Jonnagaddala , Hong Zhang , Xu Steven Xu

Graph-based medical image segmentation represents anatomical structures using boundary graphs, providing fixed-topology landmarks and inherent population-level correspondences. However, their clinical adoption has been hindered by a major…

Computer Vision and Pattern Recognition · Computer Science 2026-02-25 Nicolás Gaggion , Maria J. Ledesma-Carbayo , Stergios Christodoulidis , Maria Vakalopoulou , Enzo Ferrante

We present VGGT, a feed-forward neural network that directly infers all key 3D attributes of a scene, including camera parameters, point maps, depth maps, and 3D point tracks, from one, a few, or hundreds of its views. This approach is a…

Computer Vision and Pattern Recognition · Computer Science 2025-03-17 Jianyuan Wang , Minghao Chen , Nikita Karaev , Andrea Vedaldi , Christian Rupprecht , David Novotny

Different from Object Detection, Visual Grounding deals with detecting a bounding box for each text-image pair. This one box for each text-image data provides sparse supervision signals. Although previous works achieve impressive results,…

Computer Vision and Pattern Recognition · Computer Science 2024-07-09 Weitai Kang , Gaowen Liu , Mubarak Shah , Yan Yan

Vision foundation models trained on discretely sampled images achieve strong performance on classification benchmarks, yet whether their representations encode the continuous processes underlying their training data remains unclear. This…

Computer Vision and Pattern Recognition · Computer Science 2026-01-30 Pritika Vig , Ren-Chin Wu , William Lotter

Pangenome variation graphs (PVGs) allow for the representation of genetic diversity in a more nuanced way than traditional reference-based approaches. Here we focus on how PVGs are a powerful tool for studying genetic variation in viruses,…

Genomics · Quantitative Biology 2025-06-18 Tim Downing

General-purpose vision-language models demonstrate strong performance in everyday domains but struggle with specialized technical fields requiring precise terminology, structured reasoning, and adherence to engineering standards. This work…

Computer Vision and Pattern Recognition · Computer Science 2026-04-10 Blessing Agyei Kyem , Joshua Kofi Asamoah , Anthony Dontoh , Armstrong Aboah

Advances in AI have introduced several strong models in computational pathology to usher it into the era of multi-modal diagnosis, analysis, and interpretation. However, the current pathology-specific visual language models still lack…

Visual grounding aims to predict the locations of target objects specified by textual descriptions. For this task with linguistic and visual modalities, there is a latest research line that focuses on only selecting the linguistic-relevant…

Computer Vision and Pattern Recognition · Computer Science 2025-10-14 Jingchao Wang , Wenlong Zhang , Dingjiang Huang , Hong Wang , Yefeng Zheng

Pathology foundation models (PFMs) have rapidly advanced and are becoming a common backbone for downstream clinical tasks, offering strong transferability across tissues and institutions. However, for dense prediction (e.g., segmentation),…

Image and Video Processing · Electrical Eng. & Systems 2026-02-05 Weiming Chen , Xitong Ling , Xidong Wang , Zhenyang Cai , Yijia Guo , Mingxi Fu , Ziyi Zeng , Minxi Ouyang , Jiawen Li , Yizhi Wang , Tian Guan , Benyou Wang , Yonghong He
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