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Test-time adaptation (TTA) refers to adapting a trained model to a new domain during testing. Existing TTA techniques rely on having multiple test images from the same domain, yet this may be impractical in real-world applications such as…

Computer Vision and Pattern Recognition · Computer Science 2024-02-19 Haoyu Dong , Nicholas Konz , Hanxue Gu , Maciej A. Mazurowski

The scarcity of annotated data in specialized domains such as medical imaging presents significant challenges to training robust vision models. While self-supervised masked image modeling (MIM) offers a promising solution, existing…

Computer Vision and Pattern Recognition · Computer Science 2025-10-07 Ruilang Wang , Shuotong Xu , Bowen Liu , Runlin Huang , Donglong Chen , Weifeng Su

Deep segmentation models that generalize to images with unknown appearance are important for real-world medical image analysis. Retraining models leads to high latency and complex pipelines, which are impractical in clinical settings. The…

Image and Video Processing · Electrical Eng. & Systems 2021-01-12 Zhendong Liu , Xiaoqiong Huang , Xin Yang , Rui Gao , Rui Li , Yuanji Zhang , Yankai Huang , Guangquan Zhou , Yi Xiong , Alejandro F Frangi , Dong Ni

Medical image segmentation is vital for modern healthcare and is a key element of computer-aided diagnosis. While recent advancements in computer vision have explored unsupervised segmentation using pre-trained models, these methods have…

Computer Vision and Pattern Recognition · Computer Science 2025-08-07 Mosong Ma , Tania Stathaki , Michalis Lazarou

Molecular representation learning is fundamental for many drug related applications. Most existing molecular pre-training models are limited in using single molecular modality, either SMILES or graph representation. To effectively leverage…

Machine Learning · Computer Science 2024-11-05 Shikun Feng , Lixin Yang , Yanwen Huang , Yuyan Ni , Weiying Ma , Yanyan Lan

Multimodal learning seeks to combine data from multiple input sources to enhance the performance of different downstream tasks. In real-world scenarios, performance can degrade substantially if some input modalities are missing. Existing…

Machine Learning · Computer Science 2024-10-10 Niki Nezakati , Md Kaykobad Reza , Ameya Patil , Mashhour Solh , M. Salman Asif

Brain MRI scans are often found in four modalities, consisting of T1-weighted with and without contrast enhancement (T1ce and T1w), T2-weighted imaging (T2w), and Flair. Leveraging complementary information from these different modalities…

Image and Video Processing · Electrical Eng. & Systems 2025-09-22 Bhavesh Sandbhor , Bheeshm Sharma , Balamurugan Palaniappan

Medical imaging is a cornerstone of modern healthcare, driving advancements in diagnosis, treatment planning, and patient care. Among its various tasks, segmentation remains one of the most challenging problem due to factors such as data…

Computer Vision and Pattern Recognition · Computer Science 2025-05-15 Fares Bougourzi , Abdenour Hadid

Widely used traditional supervised deep learning methods require a large number of training samples but often fail to generalize on unseen datasets. Therefore, a more general application of any trained model is quite limited for medical…

Computer Vision and Pattern Recognition · Computer Science 2022-02-01 Rabindra Khadga , Debesh Jha , Steven Hicks , Vajira Thambawita , Michael A. Riegler , Sharib Ali , Pål Halvorsen

Efficient and robust 3D scene representation is crucial in autonomous driving, robotics, and related fields. While RGB images provide valuable content for 3D reconstruction, other modalities like thermal or depth can enable additional…

Computer Vision and Pattern Recognition · Computer Science 2026-05-29 Manoj Biswanath , Chenxin Cai , Hannah Schieber , Daniel Roth , Benjamin Busam

Semi-supervised domain generalization (SSDG) in medical image segmentation offers a promising solution for generalizing to unseen domains during testing, addressing domain shift challenges and minimizing annotation costs. However,…

Computer Vision and Pattern Recognition · Computer Science 2025-09-26 Jincai Song , Haipeng Chen , Jun Qin , Na Zhao

Despite advances in machine learning-based medical image classifiers, the safety and reliability of these systems remain major concerns in practical settings. Existing auditing approaches mainly rely on unimodal features or metadata-based…

Computer Vision and Pattern Recognition · Computer Science 2026-03-02 Yixuan Liu , Kanwal K. Bhatia , Ahmed E. Fetit

Unpaired Multi-Modal Learning (UMML) which leverages unpaired multi-modal data to boost model performance on each individual modality has attracted a lot of research interests in medical image analysis. However, existing UMML methods…

Computer Vision and Pattern Recognition · Computer Science 2025-03-10 Lei Zhu , Yanyu Xu , Huazhu Fu , Xinxing Xu , Rick Siow Mong Goh , Yong Liu

In the field of medical image segmentation, tackling Out-of-Distribution (OOD) segmentation tasks in a cost-effective manner remains a significant challenge. Universal segmentation models is a solution, which aim to generalize across the…

Computer Vision and Pattern Recognition · Computer Science 2024-05-31 Lingdong Shen , Fangxin Shang , Xiaoshuang Huang , Yehui Yang , Haifeng Huang , Shiming Xiang

Segmentation of anatomical structures and pathological regions in medical images is essential for modern clinical diagnosis, disease research, and treatment planning. While significant advancements have been made in deep learning-based…

Computer Vision and Pattern Recognition · Computer Science 2025-02-18 Taha Koleilat , Hojat Asgariandehkordi , Hassan Rivaz , Yiming Xiao

Medical data poses a daunting challenge for AI algorithms: it exists in many different modalities, experiences frequent distribution shifts, and suffers from a scarcity of examples and labels. Recent advances, including transformers and…

Although segmenting natural images has shown impressive performance, these techniques cannot be directly applied to medical image segmentation. Medical image segmentation is particularly complicated by inherent uncertainties. For instance,…

Image and Video Processing · Electrical Eng. & Systems 2024-08-06 Jiayuan Zhu , Junde Wu

Computational pathology holds substantial promise for improving diagnosis and guiding treatment decisions. Recent pathology foundation models enable the extraction of rich patch-level representations from large-scale whole-slide images…

Computer Vision and Pattern Recognition · Computer Science 2025-11-20 Xiangde Luo , Jinxi Xiang , Yuanfeng Ji , Ruijiang Li

Segmentation models are important tools for the detection and analysis of lesions in brain MRI. Depending on the type of brain pathology that is imaged, MRI scanners can acquire multiple, different image modalities (contrasts). Most…

Computer Vision and Pattern Recognition · Computer Science 2025-09-12 Anthony P. Addison , Felix Wagner , Wentian Xu , Natalie Voets , Konstantinos Kamnitsas

In medical vision, different imaging modalities provide complementary information. However, in practice, not all modalities may be available during inference or even training. Previous approaches, e.g., knowledge distillation or image…

Computer Vision and Pattern Recognition · Computer Science 2023-08-23 Aishik Konwer , Xiaoling Hu , Joseph Bae , Xuan Xu , Chao Chen , Prateek Prasanna