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Generalization is an important attribute of machine learning models, particularly for those that are to be deployed in a medical context, where unreliable predictions can have real world consequences. While the failure of models to…
Vision-Language Pre-training (VLP) has shown the merits of analysing medical images, by leveraging the semantic congruence between medical images and their corresponding reports. It efficiently learns visual representations, which in turn…
Robust and accurate segmentation of scenes has become one core functionality in various visual recognition and navigation tasks. This has inspired the recent development of Segment Anything Model (SAM), a foundation model for general mask…
Due to the scarcity of annotated data and the substantial computational costs of model, conventional tuning methods in medical image segmentation face critical challenges. Current approaches to adapting pretrained models, including…
Digital pathology based on whole slide images (WSIs) plays a key role in cancer diagnosis and clinical practice. Due to the high resolution of the WSI and the unavailability of patch-level annotations, WSI classification is usually…
The rapidly emerging field of deep learning-based computational pathology has shown promising results in utilizing whole slide images (WSIs) to objectively prognosticate cancer patients. However, most prognostic methods are currently…
Due to the scarcity of labeled data, self-supervised learning (SSL) has gained much attention in 3D medical image segmentation, by extracting semantic representations from unlabeled data. Among SSL strategies, Masked image modeling (MIM)…
Multi-modality imaging is widely used in clinical practice and biomedical research to gain a comprehensive understanding of an imaging subject. Currently, multi-modality imaging is accomplished by post hoc fusion of independently…
Spatial Transcriptomics (ST) enables the measurement of gene expression while preserving spatial information, offering critical insights into tissue architecture and disease pathology. Recent developments have explored the use of…
Recent advances in representation learning often rely on holistic embeddings that entangle multiple semantic components, limiting interpretability and generalization. These issues are especially critical in medical imaging, where downstream…
Accurate brain tumor segmentation is essential for preoperative evaluation and personalized treatment. Multi-modal MRI is widely used due to its ability to capture complementary tumor features across different sequences. However, in…
Multimodal models ideally should generalize to unseen domains while remaining data-efficient to reduce annotation costs. To this end, we introduce and study a new problem, Semi-Supervised Multimodal Domain Generalization (SSMDG), which aims…
Image matching for both cross-view and cross-modality plays a critical role in multimodal perception. In practice, the modality gap caused by different imaging systems/styles poses great challenges to the matching task. Existing works try…
The performance of supervised deep learning methods for medical image segmentation is often limited by the scarcity of labeled data. As a promising research direction, semi-supervised learning addresses this dilemma by leveraging unlabeled…
The use of diverse modalities, such as omics, medical images, and clinical data can not only improve the performance of prognostic models but also deepen an understanding of disease mechanisms and facilitate the development of novel…
Domain Generalized Semantic Segmentation (DGSS) seeks to utilize source domain data exclusively to enhance the generalization of semantic segmentation across unknown target domains. Prevailing studies predominantly concentrate on feature…
Single-source domain generalization (SDG) in medical image segmentation remains a significant challenge, particularly for images with varying color distributions and qualities. Previous approaches often struggle when models trained on…
Recent advances in multimodal large language models have enabled unified processing of visual and textual inputs, offering promising applications in general-purpose medical AI. However, their ability to generalize compositionally across…
Medical image segmentation plays a crucial role in AI-assisted diagnostics, surgical planning, and treatment monitoring. Accurate and robust segmentation models are essential for enabling reliable, data-driven clinical decision making…
Domain Generalization (DG) aims to enhance model robustness in unseen or distributionally shifted target domains through training exclusively on source domains. Although existing DG techniques, such as data manipulation, learning…