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Large language models (LLMs) have emerged as powerful tools in chemistry, significantly impacting molecule design, property prediction, and synthesis optimization. This review highlights LLM capabilities in these domains and their potential…

Machine Learning · Computer Science 2024-11-18 Mayk Caldas Ramos , Christopher J. Collison , Andrew D. White

Existing learning-based autonomous driving (AD) systems face challenges in comprehending high-level information, generalizing to rare events, and providing interpretability. To address these problems, this work employs Large Language Models…

Robotics · Computer Science 2025-04-16 Hao Sha , Yao Mu , Yuxuan Jiang , Li Chen , Chenfeng Xu , Ping Luo , Shengbo Eben Li , Masayoshi Tomizuka , Wei Zhan , Mingyu Ding

Large language models (LLMs) have significantly advanced natural language understanding and demonstrated strong problem-solving abilities. Despite these successes, most LLMs still struggle with solving mathematical problems due to the…

Computation and Language · Computer Science 2024-06-27 Meng Fang , Xiangpeng Wan , Fei Lu , Fei Xing , Kai Zou

Large Language Models (LLMs) have succeeded remarkably in various natural language processing (NLP) tasks, yet their reasoning capabilities remain a fundamental challenge. While LLMs exhibit impressive fluency and factual recall, their…

Computation and Language · Computer Science 2025-05-29 Avinash Patil , Aryan Jadon

Large vision-language models (VLMs) have garnered increasing interest in autonomous driving areas, due to their advanced capabilities in complex reasoning tasks essential for highly autonomous vehicle behavior. Despite their potential,…

Computer Vision and Pattern Recognition · Computer Science 2024-07-23 Ming Nie , Renyuan Peng , Chunwei Wang , Xinyue Cai , Jianhua Han , Hang Xu , Li Zhang

Large Language models (LLMs) have emerged as powerful tools for addressing challenges across diverse domains. Notably, recent studies have demonstrated that large language models significantly enhance the efficiency of biomolecular analysis…

Computation and Language · Computer Science 2025-03-07 Jiyue Jiang , Zikang Wang , Yuheng Shan , Heyan Chai , Jiayi Li , Zixian Ma , Xinrui Zhang , Yu Li

Large Language Models (LLMs) possess substantial reasoning capabilities and are increasingly applied to optimization tasks, particularly in synergy with evolutionary computation. However, while recent surveys have explored specific aspects…

Neural and Evolutionary Computing · Computer Science 2026-01-08 Yisong Zhang , Ran Cheng , Guoxing Yi , Kay Chen Tan

The integration of Large Language Models (LLMs) into the drug discovery and development field marks a significant paradigm shift, offering novel methodologies for understanding disease mechanisms, facilitating drug discovery, and optimizing…

Quantitative Methods · Quantitative Biology 2024-09-10 Yizhen Zheng , Huan Yee Koh , Maddie Yang , Li Li , Lauren T. May , Geoffrey I. Webb , Shirui Pan , George Church

Multimodal large language models (MLLMs) have emerged as powerful tools for computational pathology, offering unprecedented opportunities to integrate pathological images with language context for comprehensive diagnostic analysis. These…

Image and Video Processing · Electrical Eng. & Systems 2025-08-20 Zhe Xu , Ziyi Liu , Junlin Hou , Jiabo Ma , Cheng Jin , Yihui Wang , Zhixuan Chen , Zhengyu Zhang , Fuxiang Huang , Zhengrui Guo , Fengtao Zhou , Yingxue Xu , Xi Wang , Ronald Cheong Kin Chan , Li Liang , Hao Chen

Modern transportation systems face pressing challenges due to increasing demand, dynamic environments, and heterogeneous information integration. The rapid evolution of Large Language Models (LLMs) offers transformative potential to address…

Artificial Intelligence · Computer Science 2025-06-24 Tong Nie , Jian Sun , Wei Ma

Path planning is a fundamental scientific problem in robotics and autonomous navigation, requiring the derivation of efficient routes from starting to destination points while avoiding obstacles. Traditional algorithms like A* and its…

Robotics · Computer Science 2025-04-10 Silin Meng , Yiwei Wang , Cheng-Fu Yang , Nanyun Peng , Kai-Wei Chang

The rapid expansion of modern wide-area networks (WANs) has made traffic engineering (TE) increasingly challenging, as traditional solvers struggle to keep pace. Although existing offline ML-driven approaches accelerate TE optimization with…

Networking and Internet Architecture · Computer Science 2026-02-03 Xinyu Yuan , Yan Qiao , Zonghui Wang , Meng Li , Wenzhi Chen

High-content perturbation experiments allow scientists to probe biomolecular systems at unprecedented resolution, but experimental and analysis costs pose significant barriers to widespread adoption. Machine learning has the potential to…

Artificial Intelligence · Computer Science 2025-03-03 Menghua Wu , Russell Littman , Jacob Levine , Lin Qiu , Tommaso Biancalani , David Richmond , Jan-Christian Huetter

As large language models (LLMs) are widely deployed as domain-specific agents, many benchmarks have been proposed to evaluate their ability to follow instructions and make decisions in real-world scenarios. However, business scenarios often…

Computation and Language · Computer Science 2026-01-15 Jiaming Wang , Zhe Tang , Zehao Jin , Hefei Chen , Yilin Jin , Peng Ding , Xiaoyu Li , Xuezhi Cao

Large language models (LLMs) are a class of artificial intelligence models based on deep learning, which have great performance in various tasks, especially in natural language processing (NLP). Large language models typically consist of…

Quantitative Methods · Quantitative Biology 2025-02-04 Jiajia Liu , Mengyuan Yang , Yankai Yu , Haixia Xu , Tiangang Wang , Kang Li , Xiaobo Zhou

Building on their demonstrated ability to perform a variety of tasks, we investigate the application of large language models (LLMs) to enhance in-depth analytical reasoning within the context of intelligence analysis. Intelligence analysts…

Computation and Language · Computer Science 2024-11-26 Raquib Bin Yousuf , Nicholas Defelice , Mandar Sharma , Shengzhe Xu , Naren Ramakrishnan

Large language models (LLMs) integrated with autonomous agents hold significant potential for advancing scientific discovery through automated reasoning and task execution. However, applying LLM agents to drug discovery is still constrained…

Artificial Intelligence · Computer Science 2025-07-29 Kun Li , Zhennan Wu , Shoupeng Wang , Jia Wu , Shirui Pan , Wenbin Hu

We explore the geospatial reasoning capabilities of Large Language Models (LLMs), specifically, whether LLMs can read road network maps and perform navigation. We frame trajectory recovery as a proxy task, which requires models to…

Artificial Intelligence · Computer Science 2025-10-03 Thinh Hung Truong , Jey Han Lau , Jianzhong Qi

Recent advances in large language models (LLMs) have shown promising results in medical diagnosis, with some studies indicating superior performance compared to human physicians in specific scenarios. However, the diagnostic capabilities of…

Artificial Intelligence · Computer Science 2025-03-24 Zhoujian Sun , Ziyi Liu , Cheng Luo , Jiebin Chu , Zhengxing Huang

Large Language Models (LLMs) have rapidly become important tools in Biomedical and Health Informatics (BHI), enabling new ways to analyze data, treat patients, and conduct research. This study aims to provide a comprehensive overview of LLM…

Digital Libraries · Computer Science 2024-07-30 Huizi Yu , Lizhou Fan , Lingyao Li , Jiayan Zhou , Zihui Ma , Lu Xian , Wenyue Hua , Sijia He , Mingyu Jin , Yongfeng Zhang , Ashvin Gandhi , Xin Ma