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Recent advances in large language models (LLMs) have enabled a new class of AI agents that automate multiple stages of the data science workflow by integrating planning, tool use, and multimodal reasoning across text, code, tables, and…

The question-answering system for Life science research, which is characterized by the rapid pace of discovery, evolving insights, and complex interactions among knowledge entities, presents unique challenges in maintaining a comprehensive…

Computation and Language · Computer Science 2024-08-15 Chengrui Wang , Qingqing Long , Meng Xiao , Xunxin Cai , Chengjun Wu , Zhen Meng , Xuezhi Wang , Yuanchun Zhou

Large Language Models (LLMs) demonstrate ever-increasing abilities in mathematical and algorithmic tasks, yet their geometric reasoning skills are underexplored. We investigate LLMs' abilities in constructive geometric problem-solving one…

Computation and Language · Computer Science 2024-09-23 Spyridon Mouselinos , Henryk Michalewski , Mateusz Malinowski

A wide range of real-world applications is characterized by their symbolic nature, necessitating a strong capability for symbolic reasoning. This paper investigates the potential application of Large Language Models (LLMs) as symbolic…

Computation and Language · Computer Science 2024-01-18 Meng Fang , Shilong Deng , Yudi Zhang , Zijing Shi , Ling Chen , Mykola Pechenizkiy , Jun Wang

Large Language Models (LLMs) have shown remarkable performance in various natural language processing tasks but face challenges in mathematical reasoning, where complex problem-solving requires both linguistic understanding and mathematical…

Computation and Language · Computer Science 2025-03-20 Shuguang Chen , Guang Lin

Large Language Models (LLMs) are revolutionizing bioinformatics, enabling advanced analysis of DNA, RNA, proteins, and single-cell data. This survey provides a systematic review of recent advancements, focusing on genomic sequence modeling,…

Computation and Language · Computer Science 2026-03-03 Zhenyu Wang , Zikang Wang , Jiyue Jiang , Pengan Chen , Xiangyu Shi , Yu Li

In recent years, Large Language Models (LLMs) have emerged as transformative tools across numerous domains, impacting how professionals approach complex analytical tasks. This systematic mapping study comprehensively examines the…

Computers and Society · Computer Science 2025-08-19 Sai Sanjna Chintakunta , Nathalia Nascimento , Everton Guimaraes

Large Language Models (LLMs) have enabled automated heuristic design (AHD) for combinatorial optimization problems (COPs), but existing frameworks' reliance on fixed evolutionary rules and static prompt templates often leads to myopic…

Artificial Intelligence · Computer Science 2026-05-26 Oguzhan Gungordu , Siheng Xiong , Faramarz Fekri

The rapid rise of Large Language Models (LLMs) is transforming traffic and transportation research, with significant advancements emerging between the years 2023 and 2025 -- a period marked by the inception and swift growth of adopting and…

Computational Engineering, Finance, and Science · Computer Science 2025-03-28 Yimo Yan , Yejia Liao , Guanhao Xu , Ruili Yao , Huiying Fan , Jingran Sun , Xia Wang , Jonathan Sprinkle , Ziyan An , Meiyi Ma , Xi Cheng , Tong Liu , Zemian Ke , Bo Zou , Matthew Barth , Yong-Hong Kuo

Large language models (LLMs), such as GPT3.5, GPT4 and LLAMA2 perform surprisingly well and outperform human experts on many tasks. However, in many domain-specific evaluations, these LLMs often suffer from hallucination problems due to…

Computation and Language · Computer Science 2024-04-19 Yuqi Wang , Boran Jiang , Yi Luo , Dawei He , Peng Cheng , Liangcai Gao

Hypothesis generation in biomedical research has traditionally centered on uncovering hidden relationships within vast scientific literature, often using methods like Literature-Based Discovery (LBD). Despite progress, current approaches…

Computation and Language · Computer Science 2025-11-13 Fuyi Yang , Chenchen Ye , Mingyu Derek Ma , Yijia Xiao , Matthew Yang , Wei Wang

Large language models (LLMs) have fueled many intelligent web agents, but most existing ones perform far from satisfying in real-world web navigation tasks due to three factors: (1) the complexity of HTML text data (2) versatility of…

Computation and Language · Computer Science 2024-10-15 Hanyu Lai , Xiao Liu , Iat Long Iong , Shuntian Yao , Yuxuan Chen , Pengbo Shen , Hao Yu , Hanchen Zhang , Xiaohan Zhang , Yuxiao Dong , Jie Tang

Reasoning is a fundamental aspect of human intelligence that plays a crucial role in activities such as problem solving, decision making, and critical thinking. In recent years, large language models (LLMs) have made significant progress in…

Computation and Language · Computer Science 2023-05-29 Jie Huang , Kevin Chen-Chuan Chang

While large language models (LLMs) have demonstrated impressive capabilities across various natural language processing tasks by acquiring rich factual knowledge from their broad training data, their ability to synthesize and logically…

Computation and Language · Computer Science 2024-07-31 Tianshi Zheng , Jiaxin Bai , Yicheng Wang , Tianqing Fang , Yue Guo , Yauwai Yim , Yangqiu Song

Predicting enzymatic reactions is crucial for applications in biocatalysis, metabolic engineering, and drug discovery, yet it remains a complex and resource-intensive task. Large Language Models (LLMs) have recently demonstrated remarkable…

Artificial Intelligence · Computer Science 2025-05-12 Lorenzo Di Fruscia , Jana Marie Weber

Understanding travelers' route choices can help policymakers devise optimal operational and planning strategies for both normal and abnormal circumstances. However, existing choice modeling methods often rely on predefined assumptions and…

Machine Learning · Computer Science 2025-11-04 Leizhen Wang , Peibo Duan , Zhengbing He , Cheng Lyu , Xin Chen , Nan Zheng , Li Yao , Zhenliang Ma

Large Language Model (LLM)-based agents have recently shown impressive capabilities in complex reasoning and tool use via multi-step interactions with their environments. While these agents have the potential to tackle complicated tasks,…

Artificial Intelligence · Computer Science 2025-11-04 Jiaye Lin , Yifu Guo , Yuzhen Han , Sen Hu , Ziyi Ni , Licheng Wang , Mingguang Chen , Hongzhang Liu , Ronghao Chen , Yangfan He , Daxin Jiang , Binxing Jiao , Chen Hu , Huacan Wang

The use of generative artificial intelligence (AI) models is becoming ubiquitous in many fields. Though progress continues to be made, general purpose large language AI models (LLM) show a tendency to deliver creative answers, often called…

Molecular Networks · Quantitative Biology 2025-07-08 Pranta Saha , Joyce Reimer , Brook Byrns , Connor Burbridge , Neeraj Dhar , Jeffrey Chen , Steven Rayan , Gordon Broderick

Large Language Models (LLMs) have demonstrated remarkable capabilities in various reasoning and generation tasks. However, their proficiency in complex causal reasoning, discovery, and estimation remains an area of active development, often…

Artificial Intelligence · Computer Science 2025-09-03 Adib Bazgir , Amir Habibdoust , Yuwen Zhang , Xing Song

Rapid advancements in imaging techniques and analytical methods over the past decade have revolutionized our ability to comprehensively probe the biological world at multiple scales, pinpointing the type, quantity, location, and even…

Artificial Intelligence · Computer Science 2025-10-02 Shanghang Zhang , Gaole Dai , Tiejun Huang , Jianxu Chen