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Related papers: Bancroft: Genomics Acceleration Beyond On-Device M…

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Though CNNs are highly parallel workloads, in the absence of efficient on-chip memory reuse techniques, an accelerator for them quickly becomes memory bound. In this paper, we propose a CNN accelerator design for inference that is able to…

Distributed, Parallel, and Cluster Computing · Computer Science 2025-08-26 Kingshuk Majumder , Shubham Nema , Uday Bondhugula

This paper introduces HEPPO-GAE, an FPGA-based accelerator designed to optimize the Generalized Advantage Estimation (GAE) stage in Proximal Policy Optimization (PPO). Unlike previous approaches that focused on trajectory collection and…

Hardware Architecture · Computer Science 2025-07-22 Hazem Taha , Ameer M. S. Abdelhadi

Neural networks (NNs) have demonstrated their potential in a wide range of applications such as image recognition, decision making or recommendation systems. However, standard NNs are unable to capture their model uncertainty which is…

Hardware Architecture · Computer Science 2021-12-02 Hongxiang Fan , Martin Ferianc , Miguel Rodrigues , Hongyu Zhou , Xinyu Niu , Wayne Luk

Modern analytics and recommendation systems are increasingly based on graph data that capture the relations between entities being analyzed. Practical graphs come in huge sizes, offer massive parallelism, and are stored in sparse-matrix…

Distributed, Parallel, and Cluster Computing · Computer Science 2021-01-18 Seung Won Min , Vikram Sharma Mailthody , Zaid Qureshi , Jinjun Xiong , Eiman Ebrahimi , Wen-mei Hwu

Haplotype phasing, the process of resolving parental allele inheritance patterns in diploid genomes, is critical for precision medicine and population genetics, yet the underlying optimization is NP-hard, posing a scalability challenge. To…

Motivation: Storage of genomic data is a major cost for the Life Sciences, effectively addressed mostly via specialized data compression methods. For the same reasons of abundance in data production, the use of Big Data technologies is seen…

Distributed, Parallel, and Cluster Computing · Computer Science 2020-07-28 Umberto Ferraro Petrillo , Francesco Palini , Giuseppe Cattaneo , Raffaele Giancarlo

Genetic Programming (GP) is a computationally intensive technique which also has a high degree of natural parallelism. Parallel computing architectures have become commonplace especially with regards Graphics Processing Units (GPU). Hence,…

Distributed, Parallel, and Cluster Computing · Computer Science 2016-01-05 Darren M. Chitty

We assess the potential of quantum computing to accelerate computation of central tasks in genomics, focusing on often-neglected theoretical limitations. We discuss state-of-the-art challenges of quantum search, optimization, and machine…

Quantum Physics · Physics 2026-01-09 Aurora Maurizio , Guglielmo Mazzola

Scientific applications produce vast amounts of data, posing grand challenges in the underlying data management and analytic tasks. Progressive compression is a promising way to address this problem, as it allows for on-demand data…

Distributed, Parallel, and Cluster Computing · Computer Science 2025-05-02 Yanliang Li , Wenbo Li , Qian Gong , Qing Liu , Norbert Podhorszki , Scott Klasky , Xin Liang , Jieyang Chen

Recently, large language models (LLMs) have achieved huge success in the natural language processing (NLP) field, driving a growing demand to extend their deployment from the cloud to edge devices. However, deploying LLMs on…

Hardware Architecture · Computer Science 2025-05-08 Yanbiao Liang , Huihong Shi , Haikuo Shao , Zhongfeng Wang

Edge AI applications increasingly require models that can learn and adapt on-device with minimal energy budget. Traditional deep learning models, while powerful, are often overparameterized, energy-hungry, and dependent on cloud…

Hardware Architecture · Computer Science 2025-06-24 Muhammad Ihsan Al Hafiz , Naresh Ravichandran , Anders Lansner , Pawel Herman , Artur Podobas

In recent years, the quantum computing community has seen an explosion of novel methods to implement non-trivial quantum computations on near-term hardware. An important direction of research has been to decompose an arbitrary entangled…

Quantum Physics · Physics 2021-11-24 Harsha Nagarajan , Owen Lockwood , Carleton Coffrin

Mass spectrometry (MS) is essential for proteomics and metabolomics but faces impending challenges in efficiently processing the vast volumes of data. This paper introduces SpecPCM, an in-memory computing (IMC) accelerator designed to…

Hardware Architecture · Computer Science 2024-11-18 Keming Fan , Ashkan Moradifirouzabadi , Xiangjin Wu , Zheyu Li , Flavio Ponzina , Anton Persson , Eric Pop , Tajana Rosing , Mingu Kang

Quantum Random Access Memory (QRAM) is a critical component for enabling data queries in superposition, which is the cornerstone of quantum algorithms. Among various QRAM architectures, the bucket-brigade model stands out due to its noise…

High Bandwidth Memory with Processing-in-Memory (HBM-PIM) offers an opportunity to reduce data movement by executing computation directly inside memory, but current commercial platforms expose limited instruction sets and require…

Hardware Architecture · Computer Science 2026-05-01 Emanuele Venieri , Simone Manoni , Alberto Florian , Jaehyun Park , Kyomin Sohn , Andrea Bartolini

Large language models have achieved remarkable capabilities through scaling, and this paper does not challenge that. It instead investigates a different question: once large models already exist, can they become more accessible to…

Performance · Computer Science 2026-05-29 Myeong Jun Jo

Deformable convolutional networks have demonstrated outstanding performance in object recognition tasks with an effective feature extraction. Unlike standard convolution, the deformable convolution decides the receptive field size using…

Distributed, Parallel, and Cluster Computing · Computer Science 2020-06-16 Saehyun Ahn , Jung-Woo Chang , Suk-Ju Kang

Sorting is at the core of many database operations, such as index creation, sort-merge joins, and user-requested output sorting. As GPUs are emerging as a promising platform to accelerate various operations, sorting on GPUs becomes a viable…

Databases · Computer Science 2017-05-22 Elias Stehle , Hans-Arno Jacobsen

Homomorphic Encryption (HE) enables users to securely outsource both the storage and computation of sensitive data to untrusted servers. Not only does HE offer an attractive solution for security in cloud systems, but lattice-based HE…

Cryptography and Security · Computer Science 2022-09-07 Kaustubh Shivdikar , Gilbert Jonatan , Evelio Mora , Neal Livesay , Rashmi Agrawal , Ajay Joshi , Jose Abellan , John Kim , David Kaeli

Large-scale genomic workflows used in precision medicine can process datasets spanning tens to hundreds of gigabytes per sample, leading to high memory spikes, intensive disk I/O, and task failures due to out-of-memory errors. Simple static…

Distributed, Parallel, and Cluster Computing · Computer Science 2025-11-21 Daniel Mas Montserrat , Ray Verma , Míriam Barrabés , Francisco M. de la Vega , Carlos D. Bustamante , Alexander G. Ioannidis