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In analyzing information streamed by sensory organs, our brains face challenges similar to those solved in statistical signal processing. This suggests that biologically plausible implementations of online signal processing algorithms may…

Neurons and Cognition · Quantitative Biology 2016-04-27 Cengiz Pehlevan , Dmitri B. Chklovskii

A central goal of neuroscience is to understand the representations formed by brain activity patterns and their connection to behavior. The classical approach is to investigate how individual neurons encode the stimuli and how their tuning…

Neurons and Cognition · Quantitative Biology 2021-04-21 Nikolaus Kriegeskorte , Xue-Xin Wei

Linear models are widely used in computational neuroimaging to identify biomarkers associated with brain pathologies. However, interpreting the learned weights remains challenging, as they do not always yield clinically meaningful insights.…

Machine Learning · Computer Science 2026-04-23 Sara Petiton , Antoine Grigis , Raphaël Vock , Edouard Duchesnay

The feedback alignment (FA) algorithm offers a biologically plausible alternative to backpropagation (BP) for training neural networks yet notably fails to scale to convolutional architectures. Modifications have been proposed to address…

Artificial Intelligence · Computer Science 2026-05-12 Jake Lance , Larry Kieu

We present a novel method for quantifying the microscopic structure of brain tissue. It is based on the automated recognition of interpretable features obtained by analyzing the shapes of cells. This contrasts with prevailing methods of…

Computer Vision and Pattern Recognition · Computer Science 2024-04-10 Kui Qian , Litao Qiao , Beth Friedman , Edward O'Donnell , David Kleinfeld , Yoav Freund

Deep convolutional neural networks (DCNNs) have demonstrated excellent performance in object recognition and have been found to share some similarities with brain visual processing. However, the substantial gap between DCNNs and human…

Image and Video Processing · Electrical Eng. & Systems 2024-07-16 Zitong Lu , Yile Wang

We propose the Neural Functional Alignment Space (NFAS), a brain-referenced representational framework for characterizing artificial neural networks on equal functional grounds. NFAS departs from conventional alignment approaches that rely…

Computer Vision and Pattern Recognition · Computer Science 2026-03-03 Ruiyu Yan , Hanqi Jiang , Yi Pan , Xiaobo Li , Tianming Liu , Xi Jiang , Lin Zhao

Neural Cellular Automata (NCA) offer a robust and interpretable approach to image classification, making them a promising choice for microscopy image analysis. However, a performance gap remains between NCA and larger, more complex…

Computer Vision and Pattern Recognition · Computer Science 2025-08-19 Chen Yang , Michael Deutges , Jingsong Liu , Han Li , Nassir Navab , Carsten Marr , Ario Sadafi

Kernel methods provide an elegant framework for developing nonlinear learning algorithms from simple linear methods. Though these methods have superior empirical performance in several real data applications, their usefulness is inhibited…

Machine Learning · Statistics 2021-05-20 Nicholas Sterge , Bharath Sriperumbudur

Cytoarchitectonic maps provide microstructural reference parcellations of the brain, describing its organization in terms of the spatial arrangement of neuronal cell bodies as measured from histological tissue sections. Recent work provided…

Image and Video Processing · Electrical Eng. & Systems 2021-06-02 Christian Schiffer , Katrin Amunts , Stefan Harmeling , Timo Dickscheid

Developing a reliable and practical face recognition system is a long-standing goal in computer vision research. Existing literature suggests that pixel-wise face alignment is the key to achieve high-accuracy face recognition. By assuming a…

Computer Vision and Pattern Recognition · Computer Science 2015-01-21 Yuting Zhang , Kui Jia , Yueming Wang , Gang Pan , Tsung-Han Chan , Yi Ma

Advanced representation learning techniques require reliable and general evaluation methods. Recently, several algorithms based on the common idea of geometric and topological analysis of a manifold approximated from the learned data…

Machine Learning · Computer Science 2022-02-15 Petra Poklukar , Vladislav Polianskii , Anastasia Varava , Florian Pokorny , Danica Kragic

Measuring similarity between incomplete data is a fundamental challenge in web mining, recommendation systems, and user behavior analysis. Traditional approaches either discard incomplete data or perform imputation as a preprocessing step,…

Machine Learning · Computer Science 2025-10-16 Yang Cao , Sikun Yang , Kai He , Wenjun Ma , Ming Liu , Yujiu Yang , Jian Weng

Metrics optimized in complex machine learning tasks are often selected in an ad-hoc manner. It is unknown how they align with human expert perception. We explore the correlations between established quantitative segmentation quality metrics…

Human physical reasoning relies on internal "body" representations - coarse, volumetric approximations that capture an object's extent and support intuitive predictions about motion and physics. While psychophysical evidence suggests humans…

Computer Vision and Pattern Recognition · Computer Science 2025-12-02 Andrey Gizdov , Andrea Procopio , Yichen Li , Daniel Harari , Tomer Ullman

We consider the problem of precision matrix estimation where, due to extraneous confounding of the underlying precision matrix, the data are independent but not identically distributed. While such confounding occurs in many scientific…

Machine Learning · Statistics 2019-07-01 Sinong Geng , Mladen Kolar , Oluwasanmi Koyejo

Due to the growing adoption of deep neural networks in many fields of science and engineering, modeling and estimating their uncertainties has become of primary importance. Despite the growing literature about uncertainty quantification in…

Machine Learning · Computer Science 2023-02-15 Brian Staber , Sébastien Da Veiga

Advances in experimental neuroscience have transformed our ability to explore the structure and function of neural circuits. At the same time, advances in machine learning have unleashed the remarkable computational power of artificial…

Neurons and Cognition · Quantitative Biology 2021-11-23 SueYeon Chung , L. F. Abbott

Random features approach has been widely used for kernel approximation in large-scale machine learning. A number of recent studies have explored data-dependent sampling of features, modifying the stochastic oracle from which random features…

Machine Learning · Computer Science 2021-11-03 Yinsong Wang , Shahin Shahrampour

Recent studies reveal striking representational alignment between artificial neural networks (ANNs) and biological brains, leading to proposals that all sufficiently capable systems converge on universal representations of reality. Here, we…

Neurons and Cognition · Quantitative Biology 2026-04-21 Victoria Bosch , Rowan Sommers , Adrien Doerig , Tim C Kietzmann
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