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X-ray fluorescence computed tomography (XFCT) is a molecular imaging technique of x-ray photons, which can be used to sense different elements or nanoparticle (NP) agents inside deep samples or tissues. XFCT has been an active research…

Medical Physics · Physics 2021-02-01 Ignacio O. Romero , Yile Fang , Michael Lun , Changqing Li

Due to the low X-ray photon utilization efficiency and low measurement sensitivity of the electron multiplying charge coupled device (EMCCD) camera setup, the collimator based narrow beam X-ray luminescence computed tomography (XLCT)…

Medical Physics · Physics 2018-03-14 Wei Zhang , Michael C Lun , Alex Anh-Tu Nguyen , Changqing Li

Non-destructive nano-imaging of the internal structure of solid matter is only feasible using hard X-rays due to their high penetration. The highest resolution images are achieved at synchrotron radiation sources (SRF), offering superior…

X-ray Fluorescence Computed Tomography(XFCT) is a prevalent experimental technique which is utilized to investigate the spatial distribution of elements in sample. The sensitivity of L-shell XFCT of some elements is lower than that of…

Instrumentation and Detectors · Physics 2014-04-30 Liu Long , Huang Yang , Ma Bo , Xu Qing , Yan Lingtong , Li Li , Feng Songlin , Feng Xiangqian

Biophotonics is an active research area in molecular imaging, genetic diagnosis and prognosis, with direct applicability in precision medicine. However, long-standing challenges of biophotonics are well known due to low signal-to-noise…

Medical Physics · Physics 2017-10-02 Michael C Lun , Wei Zhang , Yue Zhao , Jeffrey Anker , Wenxiang Cong , Ge Wang , Changqing Li

X-ray computed tomography (CT) has an indispensable role in constructing 3D images of objects made from light materials. However, limited by absorption coefficients, X-rays cannot deeply penetrate materials such as copper and lead. Here we…

Instrumentation and Detectors · Physics 2015-01-29 Burkhant Suerfu , Christopher G. Tully

X-ray computed tomography (XCT) is an important tool for high-resolution non-destructive characterization of additively-manufactured metal components. XCT reconstructions of metal components may have beam hardening artifacts such as cupping…

Image and Video Processing · Electrical Eng. & Systems 2023-09-27 Obaidullah Rahman , Singanallur V. Venkatakrishnan , Luke Scime , Paul Brackman , Curtis Frederick , Ryan Dehoff , Vincent Paquit , Amirkoushyar Ziabari

X-ray Multi-Projection Imaging (XMPI) is an emerging technology that allows for the acquisition of millions of 3D images per second in samples opaque to visible light. This breakthrough capability enables volumetric observation of fast…

X-ray luminescence is produced when contrast agents absorb energy from X-ray photons and release a portion of that energy by emitting photons in the visible and near-infrared range. X-ray luminescence computed tomography (XLCT) was…

Image and Video Processing · Electrical Eng. & Systems 2024-06-13 Yile Fang , Yibing Zhang , Changqing Li

X-Ray based computed tomography (CT) is a well-established technique for determining the three-dimensional structure of an object from its two-dimensional projections. In the past few decades, there have been significant advancements in the…

Medical Physics · Physics 2023-04-26 Dinesh Kumar , Dilworth Y. Parkinson , Jeffrey J. Donatelli

Accurate characterization of the inner surface of X-ray monocapillary optics (XMCO) is of great significance in X-ray optics research. Compared with other characterization methods, the micro computed tomography (micro-CT) method has its…

Instrumentation and Detectors · Physics 2021-10-27 Zhao Wang , Kai Pan , Shuang Zhang , Zhuxuan Duo , Zhiguo Liu , Tianxi Sun

We previously demonstrated near-field speckle scanning based x-ray imaging to be an easy-to-implement phase sensing method capable of providing both high sensitivity and high resolution. Yet, this performance combination could only be…

Medical Physics · Physics 2017-06-21 Sebastien Berujon , Eric Ziegler

In this paper, we propose an x-ray fluorescence imaging system for elemental analysis. The key idea is what we call "x-ray fluorescence sectioning". Specifically, a slit collimator in front of an x-ray tube is used to shape x-rays into a…

Medical Physics · Physics 2012-10-29 Wenxiang Cong , Ge Wang

Minibeam and microbeam radiation therapy promise improved treatment outcomes through reduced normal tissue toxicity at better tumor control rates. The lack of suitable compact radiation sources limits the clinical application of minibeams…

The formation of organized optical states in multidimensional systems is crucial for understanding light-matter interaction and advancing light-shaping technologies. Here, we report the observation of a self-localized, ultrafast pencil beam…

Due to the merit of establishing volumetric data, X-ray computed tomography (XCT) is increasingly used as a non-destructive evaluation technique in the quality control of advanced manufactured parts with complex non-line-of-sight features.…

High-resolution x-ray tomography is a common technique for biomedical research using synchrotron sources. With advancements in laboratory x-ray sources, an increasing number of experiments can be performed in the lab. In this paper, the…

Instrumentation and Detectors · Physics 2024-08-23 Till Dreier , Robin Krüger , Gustaf Bernström , Karin Tran-Lundmark , Isabel Gonçalves , Martin Bech

X-Ray Fluorescence (XRF) scanning is a widespread technique of high importance and impact since it provides chemical composition maps crucial for several scientific investigations. There are continuous requirements for larger, faster and…

Data Analysis, Statistics and Probability · Physics 2020-05-13 George Kourousias , Fulvio Billè , Roberto Borghes , Antonio Alborini , Simone Sala , Roberto Alberti , Alessandra Gianoncelli

Recent research in computational imaging largely focuses on developing machine learning (ML) techniques for image reconstruction, which requires large-scale training datasets consisting of measurement data and ground-truth images. However,…

Image and Video Processing · Electrical Eng. & Systems 2023-09-26 Maximilian B. Kiss , Sophia B. Coban , K. Joost Batenburg , Tristan van Leeuwen , Felix Lucka

We demonstrate a new computational illumination technique that achieves large space-bandwidth-time product, for quantitative phase imaging of unstained live samples in vitro. Microscope lenses can have either large field of view (FOV) or…

Optics · Physics 2015-10-16 Lei Tian , Ziji Liu , Li-Hao Yeh , Michael Chen , Jingshan Zhong , Laura Waller
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