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Imaging the bio-impedance distribution of the brain can provide initial diagnosis of acute stroke. This paper presents a compact and non-radiative tomographic modality, i.e. multi-frequency Electromagnetic Tomography (mfEMT), for the…

Applied Physics · Physics 2020-07-29 Jinxi Xiang , Yonggui Dong , Yunjie Yang

Computed Tomography (CT) is a technology that reconstructs cross-sectional images using X-ray images taken from multiple directions. In CT, hundreds of X-ray images acquired as the X-ray source and detector rotate around a central axis, are…

Image and Video Processing · Electrical Eng. & Systems 2024-12-05 Shin Kim

Conventional cone-beam CT (CBCT) can be easily compromised by scatter and beam hardening artifacts, and the entanglement of scatter and spectral effects introduces additional complexity. In this work, we present the first attempt to develop…

Medical Physics · Physics 2025-01-07 Yifan Deng , Hao Zhou , Zhilei Wang , Adam S. Wang , Hewei Gao

In recent years, neutral atom quantum computers (NAQCs) have attracted a lot of attention, primarily due to their long coherence times and good scalability. One of their main drawbacks is their comparatively time-consuming control overhead,…

Quantum Physics · Physics 2026-03-04 Jonas Winklmann , Yian Yu , Xiaorang Guo , Korbinian Staudacher , Martin Schulz

A hybrid pixel detector based on the concept of simultaneous charge integration and photon counting will be presented. The second generation of a counting and integrating X-ray prototype CMOS chip (CIX) has been operated with different…

Instrumentation and Detectors · Physics 2009-11-13 H. Krüger , J. Fink , E. Kraft , N. Wermes , P. Fischer , I. Peric , C. Herrmann , M. Overdick , W. Rütten

We develop the XCALIB toolkit to calibrate the beam profile of an X-ray free-electron laser (XFEL) at the focal spot based on the experimental charge state distributions (CSDs) of light atoms. Accurate characterization of the fluence…

Fluorescence microscopy allows for a detailed inspection of cells, cellular networks, and anatomical landmarks by staining with a variety of carefully-selected markers visualized as color channels. Quantitative characterization of…

Computer Vision and Pattern Recognition · Computer Science 2021-08-26 Alvaro Gomariz , Tiziano Portenier , Patrick M. Helbling , Stephan Isringhausen , Ute Suessbier , César Nombela-Arrieta , Orcun Goksel

X-ray time-resolved tomography is one of the most popular X-ray techniques to probe dynamics in three dimensions (3D). Recent developments in time-resolved tomography opened the possibility of recording kilohertz-rate 3D movies. However,…

Correlative microscopy is a powerful technique that combines the advantages of multiple imaging modalities to achieve a comprehensive understanding of investigated samples. For example, fluorescence microscopy provides unique functional…

An alternative approach to ultrasound computed tomography (USCT) for medical imaging is proposed, with the intent to (i) shorten acquisition time for devices with a large number of emitters, (ii) eliminate the calibration step, and (iii)…

Medical Physics · Physics 2022-01-25 Ines Elisa Ulrich , Christian Boehm , Andrea Zunino , Cyrill Bösch , Andreas Fichtner

X-ray computed tomography (CT) reconstructs the internal morphology of a three dimensional object from a collection of projection images, most commonly using a single rotation axis. However, for objects containing dense materials like…

Image and Video Processing · Electrical Eng. & Systems 2024-06-27 Diyu Yang , Craig A. J. Kemp , Soumendu Majee , Gregery T. Buzzard , Charles A. Bouman

Fourier ptychographic microscopy enables gigapixel-scale imaging, with both large field-of-view and high resolution. Using a set of low-resolution images that are recorded under varying illumination angles, the goal is to computationally…

Signal Processing · Electrical Eng. & Systems 2018-03-13 Emrah Bostan , Mahdi Soltanolkotabi , David Ren , Laura Waller

We demonstrate computerized tomography (CT) reconstructions from absorption, phase and dark-field signals obtained from scans acquired when the x-ray probe light is modulated with speckle. Two different interlaced schemes are proposed to…

Optics · Physics 2016-04-27 Sebastien Berujon , Eric Ziegler

An innovative X-ray imaging sensor with intrinsic digital characteristics is presented. It is based on Chromatic Photon Counting technology. The detector is able to count individually the incident X-ray photons and to separate them…

Instrumentation and Detectors · Physics 2015-06-11 R. Bellazzini , G. Spandre , A. Brez , M. Minuti , M. Pinchera , P. Mozzo

We present a compact sample holder equipped with electromagnets and high frequency transmission lines; the sample holder is intended for combined x-ray magnetic circular dichroism (XMCD) and ferromagnetic resonance measurements (FMR).…

Mesoscale and Nanoscale Physics · Physics 2015-05-13 D. A. Arena , Y. Ding , E. Vescovo , S. Z. Zohar , Y. Guan , W. E. Bailey

Confocal x-ray fluorescence microscopy (CXRF) allows direct detection of x-ray fluorescence from a micron-scale 3D volume of an extended, unthinned sample. We have previously demonstrated the use of a novel collection optic, fabricated from…

Instrumentation and Detectors · Physics 2016-07-07 David N Agyeman-Budu , Sanjukta Choudhury , Ian Coulthard , Robert Gordon , Emil Hallin , Arthur R Woll

X-ray phase-contrast tomography (XPCT) is widely used for high contrast 3D imaging using either synchrotron or laboratory microfocus X-ray sources. XPCT enables an order of magnitude improvement in image contrast of the reconstructed…

Image and Video Processing · Electrical Eng. & Systems 2024-10-28 K. Aditya Mohan , Jean-Baptiste Forien , Venkatesh Sridhar , Jefferson A. Cuadra , Dilworth Parkinson

Fluorescence imaging is the most widely used method for unveiling the molecular composition of biological specimens. However, the weak optical emission of fluorescent probes and the tradeoff between imaging speed and sensitivity is…

The rapid development of X-ray micro-computed tomography (micro-CT) opens new opportunities for 3D analysis of particle and grain-size characterisation, determination of particle densities and shape factors, estimation of mineral…

Machine Learning · Computer Science 2022-08-29 Patrick Kin Man Tung , Amalia Yunita Halim , Huixin Wang , Anne Rich , Christopher Marjo , Klaus Regenauer-Lieb

Hybrid photon counting detectors (HPCDs) have unlocked new capabilities for x-ray-based measurements at synchrotrons around the world in the last 30 years. By leveraging independently optimized sensor and readout layers, they offer high…