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This study demonstrates the feasibility of a novel fabrication technique for high spatial resolution CsI: Tl scintillation detectors tailored for single photon emission computed tomography (SPECT) systems. Building upon our previously…

Medical Physics · Physics 2026-02-16 Xi Zhang , Arkadiusz Sitek , Lisa Blackberg , Matthew Kupinski , Lars Furenlid , Hamid Sabet

Imaging in low-light environments is challenging due to reduced scene radiance, which leads to elevated sensor noise and reduced color saturation. Most learning-based low-light enhancement methods rely on paired training data captured under…

Computer Vision and Pattern Recognition · Computer Science 2026-04-10 Maria Pilligua , David Serrano-Lozano , Pai Peng , Ramon Baldrich , Michael S. Brown , Javier Vazquez-Corral

Fluorescence lifetime imaging microscopy (FLIM) is a powerful technique in biomedical research that uses the fluorophore decay rate to provide additional contrast in fluorescence microscopy. However, at present, the calculation, analysis,…

Image and Video Processing · Electrical Eng. & Systems 2021-06-09 Varun Mannam , Yide Zhang , Xiaotong Yuan , Cara Ravasio , Scott S. Howard

Single-molecule microscopy has become an indispensable tool for biochemical analysis. The capability of characterizing distinct properties of individual molecules without averaging has provided us with a different perspective for the…

Applied Physics · Physics 2020-05-21 Miao-Hsuan Chien , Silvan Schmid

Over the recent years, there has been an extensive adoption of Machine Learning (ML) in a plethora of real-world applications, ranging from computer vision to data mining and drug discovery. In this paper, we utilize ML to facilitate…

Materials Science · Physics 2022-02-10 Ayush Arunachalam , S. Novia Berriel , Parag Banerjee , Kanad Basu

Recent advancements in autonomous driving, augmented reality, robotics, and embodied intelligence have necessitated 3D perception algorithms. However, current 3D perception methods, especially specialized small models, exhibit poor…

Computer Vision and Pattern Recognition · Computer Science 2025-02-14 Fan Yang , Sicheng Zhao , Yanhao Zhang , Hui Chen , Haonan Lu , Jungong Han , Guiguang Ding

The technological advance of High Numerical Aperture Extreme Ultraviolet Lithography (High NA EUVL) has opened the gates to extensive researches on thinner photoresists (below 30nm), necessary for the industrial implementation of High NA…

Computer Vision and Pattern Recognition · Computer Science 2023-10-24 Sara Sacchi , Bappaditya Dey , Iacopo Mochi , Sandip Halder , Philippe Leray

We demonstrate the combination of a hemispherical solid immersion lens with a micro-photoluminescence setup. Two advantages introduced by the SIL, an improved resolution of 0.4 times the wavelength in vacuum and a 5 times enhancement of the…

Optics · Physics 2009-11-07 S. Moehl , Hui Zhao , B. Dal Don , S. Wachter , H. Kalt

The Vision Transformer (ViT) has demonstrated remarkable performance in Self-Supervised Learning (SSL) for 3D medical image analysis. Masked AutoEncoder (MAE) for feature pre-training can further unleash the potential of ViT on various…

Computer Vision and Pattern Recognition · Computer Science 2025-01-13 Jiaxin Zhuang , Linshan Wu , Qiong Wang , Peng Fei , Varut Vardhanabhuti , Lin Luo , Hao Chen

We pose that microscopy offers an ideal real-world experimental environment for the development and deployment of active Bayesian and reinforcement learning methods. Indeed, the tremendous progress achieved by machine learning (ML) and…

Disordered Systems and Neural Networks · Physics 2022-10-14 Sergei V. Kalinin , Rama Vasudevan , Yongtao Liu , Ayana Ghosh , Kevin Roccapriore , Maxim Ziatdinov

Multimodal Large Language Models (MLLMs) have made impressive progress in connecting vision and language, but they still struggle with spatial understanding and viewpoint-aware reasoning. Recent efforts aim to augment the input…

Computer Vision and Pattern Recognition · Computer Science 2026-03-19 Kevin Qu , Haozhe Qi , Mihai Dusmanu , Mahdi Rad , Rui Wang , Marc Pollefeys

Spatial intelligence in vision-language models (VLMs) attracts research interest with the practical demand to reason in the 3D world.Despite promising results, most existing methods follow the conventional 2D pipeline in VLMs and use…

Computer Vision and Pattern Recognition · Computer Science 2026-05-11 Jerry Jiang , Haowen Sun , Denis Gudovskiy , Yohei Nakata , Tomoyuki Okuno , Kurt Keutzer , Wenzhao Zheng

State space models (SSMs) have recently achieved strong performance on long sequence modeling tasks while offering improved memory and computational efficiency compared to transformer based architectures. However, their evaluation has been…

Machine Learning · Computer Science 2026-03-13 Fatemeh Valeh , Monika Farsang , Radu Grosu , Gerhard Schütz

Fine-grained facial expression editing has long been limited by intrinsic semantic overlap. To address this, we construct the Flex Facial Expression (FFE) dataset with continuous affective annotations and establish FFE-Bench to evaluate…

Computer Vision and Pattern Recognition · Computer Science 2026-03-27 Jiabin Hua , Hengyuan Xu , Aojie Li , Wei Cheng , Gang Yu , Xingjun Ma , Yu-Gang Jiang

One-shot medical image segmentation (MIS) is crucial for medical analysis due to the burden of medical experts on manual annotation. The recent emergence of the segment anything model (SAM) has demonstrated remarkable adaptation in MIS but…

Image and Video Processing · Electrical Eng. & Systems 2025-04-30 Jia Wang , Yunan Mei , Jiarui Liu , Xin Fan

Point-scanning microscopy approaches are transforming super-resolution imaging. Despite achieving parallel high-speed imaging using multifocal techniques, efficient multi-color capability with high-quality illumination is currently lacking.…

Optics · Physics 2023-03-14 Ning Xu , Sarah E. Bohndiek , Zexing Li , Cilong Zhang , Qiaofeng Tan

The point spread function (PSF) is fundamental to any type of microscopy, most importantly so for single-molecule localization techniques, where the exact PSF shape is crucial for precise molecule localization at the nanoscale. However,…

Recent work has shown impressive localization performance using only images of ground textures taken with a downward facing monocular camera. This provides a reliable navigation method that is robust to feature sparse environments and…

Robotics · Computer Science 2023-03-13 Kyle M. Hart , Brendan Englot , Ryan P. O'Shea , John D. Kelly , David Martinez

The Segment Anything Model (SAM) is a new image segmentation tool trained with the largest available segmentation dataset. The model has demonstrated that, with prompts, it can create high-quality masks for general images. However, the…

Image and Video Processing · Electrical Eng. & Systems 2024-02-06 Yihao Liu , Jiaming Zhang , Zhangcong She , Amir Kheradmand , Mehran Armand

In this paper, we introduce ILLUME, a unified multimodal large language model (MLLM) that seamlessly integrates multimodal understanding and generation capabilities within a single large language model through a unified next-token…

Computer Vision and Pattern Recognition · Computer Science 2024-12-10 Chunwei Wang , Guansong Lu , Junwei Yang , Runhui Huang , Jianhua Han , Lu Hou , Wei Zhang , Hang Xu