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Cancer is one of the leading causes of death worldwide, making the development of rapid, minimally invasive, label-free and scalable diagnostic strategies a major challenge in modern oncology. In this context, spectroscopic liquid biopsy…

Multiple Instance Learning (MIL) methods have become increasingly popular for classifying giga-pixel sized Whole-Slide Images (WSIs) in digital pathology. Most MIL methods operate at a single WSI magnification, by processing all the tissue…

Computer Vision and Pattern Recognition · Computer Science 2022-07-27 Kevin Thandiackal , Boqi Chen , Pushpak Pati , Guillaume Jaume , Drew F. K. Williamson , Maria Gabrani , Orcun Goksel

Medical imaging is critical for diagnostics, but clinical adoption of advanced AI-driven imaging faces challenges due to patient variability, image artifacts, and limited model generalization. While deep learning has transformed image…

Image and Video Processing · Electrical Eng. & Systems 2025-06-02 Abdul-mojeed Olabisi Ilyas , Adeleke Maradesa , Jamal Banzi , Jianpan Huang , Henry K. F. Mak , Kannie W. Y. Chan

In the intersection of molecular science and deep learning, tasks like virtual screening have driven the need for a high-throughput molecular representation generator on large chemical databases. However, as SMILES strings are the most…

Computational Engineering, Finance, and Science · Computer Science 2021-12-28 Wenhao Zhu , Ziyao Li , Lingsheng Cai , Guojie Song

We propose a Deep learning-based weak label learning method for analyzing whole slide images (WSIs) of Hematoxylin and Eosin (H&E) stained tumor tissue not requiring pixel-level or tile-level annotations using Self-supervised pre-training…

Image and Video Processing · Electrical Eng. & Systems 2023-06-29 Yoni Schirris , Efstratios Gavves , Iris Nederlof , Hugo Mark Horlings , Jonas Teuwen

Anomaly detection and localization in medical imaging remain critical challenges in healthcare. This paper introduces Spatial-MSMA (Multiscale Score Matching Analysis), a novel unsupervised method for anomaly localization in volumetric…

Computer Vision and Pattern Recognition · Computer Science 2024-07-19 Ahsan Mahmood , Junier Oliva , Martin Styner

Loop Closure Detection (LCD) has been proved to be extremely useful in global consistent visual Simultaneously Localization and Mapping (SLAM) and appearance-based robot relocalization. Methods exploiting binary features in bag of words…

Computer Vision and Pattern Recognition · Computer Science 2017-03-01 Lei Han , Lu Fang

Structured illumination microscopy (SIM) is an important super-resolution based microscopy technique that breaks the diffraction limit and enhances optical microscopy systems. With the development of biology and medical engineering, there…

Image and Video Processing · Electrical Eng. & Systems 2021-11-18 Xi Cheng , Jun Li , Qiang Dai , Zhenyong Fu , Jian Yang

Accurate and consistent construction of point clouds from LiDAR scanning data is fundamental for 3D modeling applications. Current solutions, such as multiview point cloud registration and LiDAR bundle adjustment, predominantly depend on…

Computer Vision and Pattern Recognition · Computer Science 2024-09-24 Jianping Li , Thien-Minh Nguyen , Shenghai Yuan , Lihua Xie

The Mid-Infrared Instrument (MIRI) for JWST is supplied with a suite of imaging bandpass filters optimized for full spectral coverage in eight intermediate-width bands from 5 to 26 microns and a narrower one at 11.3 microns. This contrasts…

We propose spatial polarization multiplexing (SPM) for joint sensing of shape and reflectance of a static or dynamic deformable object, which is also invisible to the naked eye. Past structured-light methods are limited to shape acquisition…

Computer Vision and Pattern Recognition · Computer Science 2026-01-07 Tomoki Ichikawa , Ryo Kawahara , Ko Nishino

The sparsity-restricted maximum likelihood estimator (SMLE) has received considerable attention for feature screening in ultrahigh-dimensional regression. SMLE is a computationally convenient method that naturally incorporates the joint…

Other Statistics · Statistics 2022-01-11 Qianxiang Zang , Chen Xu , Kelly Burkett

Dark Matter (DM) remains poorly probed on critical, sub-galactic scales, where predictions from different models diverge in terms of abundance and density profiles of halos. Gravitational lens systems on milli-arcsecond scales…

In existing medical Region of Interest (ROI) detection, there lacks an algorithm that can simultaneously satisfy both real-time performance and accuracy, not meeting the growing demand for automatic detection in medicine. Although the basic…

Computer Vision and Pattern Recognition · Computer Science 2024-08-27 Zhongwen Yu , Qiu Guan , Jianmin Yang , Zhiqiang Yang , Qianwei Zhou , Yang Chen , Feng Chen

The complementary fusion of light detection and ranging (LiDAR) data and image data is a promising but challenging task for generating high-precision and high-density point clouds. This study proposes an innovative LiDAR-guided stereo…

Computer Vision and Pattern Recognition · Computer Science 2022-02-25 Yongjun Zhang , Siyuan Zou , Xinyi Liu , Xu Huang , Yi Wan , Yongxiang Yao

Whole slide image (WSI) assessment is a challenging and crucial step in cancer diagnosis and treatment planning. WSIs require high magnifications to facilitate sub-cellular analysis. Precise annotations for patch- or even pixel-level…

Computer Vision and Pattern Recognition · Computer Science 2023-11-20 Simon Holdenried-Krafft , Peter Somers , Ivonne A. Montes-Majarro , Diana Silimon , Cristina Tarín , Falko Fend , Hendrik P. A. Lensch

Large language models (LLMs) have shown promising capabilities in visually interpreting medical time-series data. However, their general-purpose design can limit domain-specific precision, and the proprietary nature of many models poses…

Artificial Intelligence · Computer Science 2025-07-22 Huayu Li , Zhengxiao He , Xiwen Chen , Ci Zhang , Stuart F. Quan , William D. S. Killgore , Shu-Fen Wung , Chen X. Chen , Geng Yuan , Jin Lu , Ao Li

Monocular simultaneous localization and mapping (SLAM) is emerging in advanced driver assistance systems and autonomous driving, because a single camera is cheap and easy to install. Conventional monocular SLAM has two major challenges…

Computer Vision and Pattern Recognition · Computer Science 2022-12-16 Jinkyu Lee , Muhyun Back , Sung Soo Hwang , Il Yong Chun

Recent advances in 3D scene-language understanding have leveraged Large Language Models (LLMs) for 3D reasoning by transferring their general reasoning ability to 3D multi-modal contexts. However, existing methods typically adopt standard…

Computer Vision and Pattern Recognition · Computer Science 2026-03-25 Yerim Jeon , Miso Lee , WonJun Moon , Jae-Pil Heo

High-speed image acquisition in light microscopy is essential for a wide range of applications, including observing dynamic biological processes and enabling high-throughput sample analysis. However, traditional imaging speeds are often…