Related papers: DNA Sensing with Whispering Gallery Mode Microlase…
In recent years, there has been rapid advancement in single-molecule techniques, driven by their unparalleled precision in studying molecules whose sizes are beyond the diffraction limit. Among these techniques, optoplasmonic whispering…
Accurate, label-free quantification of multiple analytes in complex biological media remains a major challenge due to limited multiplexing, signal cross-correlations, and inconsistency across sensor samples and measurement runs. We…
Biosensing based on whispering-gallery mode (WGM) resonators has been continuously studied with great attention due to its excellent sensitivity guaranteeing the label-free detection. However, its practical impact is insignificant to date…
Recently optical whispering-gallery-mode resonators (WGMRs) have emerged as promising platforms to achieve label-free detection of nanoscale objects and to reach single molecule sensitivity. The ultimate detection performance of WGMRs are…
In this study, an integrated low-cost and complexity mm-wave structure of Whispering Gallery Mode (WGM) is proposed for sensing the glucose levels in mimicking aquatic solutions of concentrations similar to type 2 diabetics. The bio-sensor…
Observing the hybridisation kinetics of DNA probes immobilised on plasmonic nanoparticles is key in plamon enhanced fluorescence detection from weak emitting species, and refractive index based single-molecule detection on optoplasmonic…
Discerning the neurotransmitter dysregulation is a hallmark of neurological disorders and diseases, including Alzheimer's, Parkinson's, and multiple sclerosis. The concentration of neurotransmitters in the synaptic cleft is particularly…
Biophotonics - and more recently, biointegrated photonics - offer transformative tools for probing cellular processes with unprecedented precision. Among these, whispering gallery mode (WGM) resonators - optical microcavities formed in…
We develop a compact whispering-gallery-mode (WGM) sensing system by integrating multiple components, including a tunable laser, a temperature controller, a function generator, an oscilloscope, a photodiode detector, and a testing computer,…
Whispering gallery mode biosensors allow selective unlabelled detection of single proteins and, combined with quantum limited sensitivity, the possibility for noninvasive realtime observation of motor molecule motion. However, to date…
Whispering-gallery-mode (WGM) microcavities have emerged as a promising alternative to traditional ultrasound probes, offering high sensitivity and wide bandwidth. In our research, we propose a novel silica WGM microprobe device, with…
Quantum sensing with nitrogen-vacancy (NV) centers in diamond promises to revolutionize biological research and medical diagnostics. Thanks to their high sensitivity, NV sensors could, in principle, detect specific binding events with…
Genetic analysis methods are foundational to advancing personalized and preventative medicine, accelerating disease diagnostics, and monitoring the health of organisms and ecosystems. Current nucleic acid technologies such as polymerase…
Whispering gallery mode (WGM) microcavities feature ultrahigh Q-factors and small mode volumes, offering strong light-matter interactions for sensing applications. However, unmodified surfaces are weakly responsive togas-phase refractive…
Microcavity and whispering gallery mode (WGM) biosensors derive their sensitivity from monitoring frequency shifts induced by protein binding at sites of highly confined field intensities, where field strengths can be further amplified by…
Identification of non-amplified DNA sequences and single-base mutations is essential for molecular biology and genetic diagnostics. This paper reports a novel sensor consisting of electrochemically-gated graphene coplanar waveguides coupled…
A novel non-invasive microscopy technique for imaging and sizing of folded DNA molecules with the use of photovoltaic tweezers and phase-sensitive detection is elaborated and realized. This novel method is compared with the state-of-the-art…
Laser sensing has a wide range of applications. In this paper, we propose a pH sensing laser with an ultra-low threshold and low sample consumption based on a whispering-gallery-mode microbubble resonator. Rhodamine 6G aqueous solutions…
DNA nanotechnology uses predictable interactions of nucleic acids to precisely engineer complex nanostructures. Characterizing these self-assembled structures at the single-structure level is crucial for validating their design and…
Whispering-gallery mode (WGM) resonators combine small optical mode volumes with narrow resonance linewidths, making them exciting platforms for a variety of applications. Here we report a flying WGM microlaser, realized by optically…